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1:
[发明]
【中文】一种半乳糖受体介导的混合胶束口服制剂及其制备方法 【EN】Galactose receptor mediated mixed micelle oral preparation and preparation method thereof
申请号:
201810878497.5
公开号:CN110840838A 主分类号:A61K9/107
申请人:
【中文】山东大学【EN】
SHANDONG University
申请日:2018.08.03 公开日:2020.02.28
发明人:
【中文】翟光喜
;
孙思雨
;
刘卫东【EN】Zhai Guangxi
;
Sun Siyu
;
Liu Weidong
摘要:【中文】本发明涉及一种半乳糖修饰聚乙二醇‑聚乳酸(Gal‑PEG‑PLA)/聚乙二醇维生素E琥珀酸酯(TPGS)混合胶束口服制剂及其制备方法,首先将聚乳酸聚乙二醇活性酯与半乳糖胺反应合成半乳糖修饰的聚乙二醇聚乳酸,再将姜黄素原料药与半乳糖修饰的聚乙二醇聚乳酸、聚乙二醇维生素E琥珀酸酯混合,溶于有机溶剂中,旋转蒸发形成均匀薄膜,加入去离子水超声水化,离心取上清液,得到载姜黄素的半乳糖受体介导的混合胶束口服制剂。本发明利用薄膜分散技术采用Gal‑PEG‑PLA和TPGS为载体,以期促进胃肠道对姜黄素的吸收,提高药物口服生物利用度。 【EN】The invention relates to a galactose modified polyethylene glycol-polylactic acid (Gal-PEG-PLA)/polyethylene glycol vitamin E succinate (TPGS) mixed micelle oral preparation and a preparation method thereof. The invention uses Gal-PEG-PLA and TPGS as carriers by using a film dispersion technology, so as to promote the absorption of curcumin by gastrointestinal tracts and improve the oral bioavailability of the medicine.
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2:
[发明]
【中文】一种针对模糊焊缝的视觉定位方法及系统 【EN】Visual positioning method and system for fuzzy weld joint
申请号:
201910978786.7
公开号:CN110852173A 主分类号:G06K9/00
申请人:
【中文】山东大学【EN】
SHANDONG University
申请日:2019.10.15 公开日:2020.02.28
发明人:
【中文】陈桂友
;
黑振全【EN】Chen Guiyou
;
He Zhen Quan
摘要:【中文】本公开提供了一种针对模糊焊缝的视觉定位方法及系统,获取包含焊缝信息的待处理图像;对待处理图像进行预处理,去除外界环境干扰,突出焊缝的边缘特征;对焊缝进行边缘提取,计算预处理后的图像梯度幅值和方向,进行非极大值抑制,最后选取两个滞后阈值进行边缘点的连接,得到二值图像;对二值图像进行霍夫变换,检测出直线,根据直线的起始点绘制矩形框,实现焊缝准确识别并定位。 【EN】The utility model provides a visual positioning method and system for fuzzy welding seam, which obtains the image to be processed containing welding seam information; preprocessing an image to be processed, removing external environment interference, and highlighting edge characteristics of a welding line; performing edge extraction on a welding seam, calculating the gradient amplitude and direction of the preprocessed image, performing non-maximum value suppression, and finally selecting two lag thresholds to connect edge points to obtain a binary image; and carrying out Hough transformation on the binary image, detecting a straight line, drawing a rectangular frame according to the starting point of the straight line, and realizing accurate identification and positioning of the welding line.
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3:
[发明]
【中文】一种CuO@BiOI复合材料及其制备方法和应用 【EN】CuO @ BiOI composite material and preparation method and application thereof
申请号:
201910984559.5
公开号:CN110841664A 主分类号:B01J27/128
申请人:
【中文】山东大学【EN】
SHANDONG University
申请日:2019.10.16 公开日:2020.02.28
发明人:
【中文】王琦
;
张怡
;
汪宙【EN】Wang Qi
;
Zhang Yi
;
Wang Zhou
摘要:【中文】本发明提供一种Cu
2
O@BiOI复合材料及其制备方法和应用,属于光电化学传感器制造和检测分析技术领域。本发明首次将BiOI与Cu
2
O进行结合,以BiOI作为支撑材料,解决了过渡金属氧化物颗粒易团聚的问题,使Cu
2
O纳米颗粒均匀分布,增大比表面积,充分暴露催化活性位点;进一步的,将Cu
2
O纳米粒子和BiOI纳米片复合生长在基底(如FTO)上制备得到的复合电极具有高催化活性、高灵敏度、宽线性范围、良好的稳定性、高选择性和优良的光电化学性能,且该材料被证明适用于真实样品中的H
2
O
2
检测,误差极低,可以满足实际应用的需求。 【EN】The invention provides a Cu
2
An O @ BiOI composite material and a preparation method and application thereof belong to the technical field of manufacturing, detection and analysis of photoelectrochemical sensors. The invention firstly combines the BiOI and the Cu
2
O is combined, and the BiOI is taken as a supporting material, so that the problem that transition metal oxide particles are easy to agglomerate is solved, and Cu is enabled
2
The O nano particles are uniformly distributed, the specific surface area is increased, and the catalytic active sites are fully exposed; further, adding Cu
2
The composite electrode prepared by compositely growing the O nano particles and the BiOI nano sheets on a substrate (such as FTO) has high catalytic activity, high sensitivity, wide linear range, good stability, high selectivity and excellent photoelectrochemical property, and the materialProved to be suitable for H in real samples
2
O
2
Detection is carried out, the error is extremely low, and the requirements of practical application can be met.
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4:
[发明]
【中文】基于相关双采样的InGaAs短波红外相机高动态范围成像方法 【EN】High dynamic range imaging method of InGaAs short wave infrared camera based on correlated double sampling
申请号:
201910990722.9
公开号:CN110855899A 主分类号:H04N5/235
申请人:
【中文】山东大学【EN】
SHANDONG University
申请日:2019.10.18 公开日:2020.02.28
发明人:
【中文】李永富
;
费宬
;
刘俊良
;
刘兆军
;
赵显
;
方家熊【EN】Li Yongfu
;
Fei Cheng
;
Liu Junliang
;
Liu Zhaojun
;
Zhao Xian
;
Fang Jiaxiong
摘要:【中文】本发明属于红外成像技术领域,涉及一种短波红外相机高动态范围成像方法。一种基于相关双采样的InGaAs短波红外相机高动态范围成像方法,包括:设定InGaAs短波红外相机所采集原始数据和HDR数据的位数,确定HDR倍率hdr_mul_factor;确定HDR阈值hdr_th;确定相机的背景响应bg;设定积分时间T
1
和T
2
,根据积分时间和HDR阈值hdr_th,判断像元是否进入HDR模式;计算像元的响应,读取所有像元的响应,完成成像。本发明的方法基于InGaAs短波红外相机的相关双采样功能实现了短波红外波段的HDR成像,高效且便于实现,能够获得具有更高图像亮度和对比度范围的图像,更好地反映真实环境中的视觉效果。 【EN】The invention belongs to the technical field of infrared imaging, and relates to a high dynamic range imaging method of a short wave infrared camera. A high dynamic range imaging method of an InGaAs short wave infrared camera based on correlated double sampling comprises the following steps: setting the digits of original data and HDR data acquired by the InGaAs short-wave infrared camera, and determining HDR multiplying power HDR _ mul _ factor; determining an HDR threshold HDR _ th; determining a background response bg of the camera; setting the integration time T
1
And T
2
Judging whether the pixel enters an HDR mode or not according to the integration time and the HDR threshold HDR _ th; and calculating the response of the pixel, reading the response of all the pixels and finishing imaging. The method realizes HDR imaging of the short wave infrared band based on the related double sampling function of the InGaAs short wave infrared camera, is efficient and convenient to realize, can obtain images with higher image brightness and contrast range, and better reflects the visual effect in a real environment.
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5:
[发明]
【中文】基于人工智能的隧道内仿生摄像装置及方法 【EN】Tunnel bionic camera device and method based on artificial intelligence
申请号:
201911032814.2
公开号:CN110855939A 主分类号:H04N7/18
申请人:
【中文】山东大学【EN】
SHANDONG University
申请日:2019.10.28 公开日:2020.02.28
发明人:
【中文】薛翊国
;
李广坤
;
邱道宏
;
苏茂鑫
;
公惠民【EN】Xue Yiguo
;
Li Guangkun
;
Qiu Daohong
;
Su Maoxin
;
Gong Huimin
摘要:【中文】本发明公开了一种基于人工智能的隧道内仿生摄像装置及方法,包括壳体,壳体上设有探测系统、自动报警系统、控制系统和无线传输系统;探测系统对四周进行全方位的实时探测;在壳体的正前方的若干“复眼”摄像头,实时多角度范围采集隧道内的高清图像;距离传感器、“复眼”摄像头均与控制系统相连,控制系统根据距离传感器和“复眼”摄像头探测的目标体位置信息进行实时计算各个时刻的目标体位置信息判定是否启动自动报警系统;且控制系统通过无线传输系统将仿生摄像装置拍摄到的洞内施工状态和掌子面情况实时传输到远程服务端,并接收远程服务端的控制指令。本发明基于仿生学的结构设计具有安全高效、方便快捷、监测结果准确等优点。 【EN】The invention discloses a bionic camera device and a method in a tunnel based on artificial intelligence, which comprises a shell, wherein the shell is provided with a detection system, an automatic alarm system, a control system and a wireless transmission system; the detection system detects the surrounding in all directions in real time; a plurality of compound eye cameras in front of the shell collect high-definition images in the tunnel in real time in a multi-angle range; the distance sensor and the compound eye camera are connected with the control system, and the control system calculates the position information of the target body at each moment in real time according to the position information of the target body detected by the distance sensor and the compound eye camera to judge whether to start the automatic alarm system; and the control system transmits the construction state and the tunnel face condition in the tunnel shot by the bionic camera device to the remote server in real time through the wireless transmission system and receives a control instruction of the remote server. The bionic structure-based design has the advantages of safety, high efficiency, convenience, rapidness, accurate monitoring result and the like.
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6:
[发明]
【中文】一种园区级综合能源系统辅助设计方法及系统 【EN】Park level comprehensive energy system aided design method and system
申请号:
201911081957.2
公开号:CN110851892A 主分类号:G06F30/00
申请人:
【中文】山东大学【EN】
SHANDONG University
申请日:2019.11.07 公开日:2020.02.28
发明人:
【中文】孙波
;
李一鸣
;
刘澈
;
周宝斌
;
张承慧【EN】Sun Bo
;
Li Yiming
;
Liu Che
;
Zhou Baobin
;
Zhang Chenghui
摘要:【中文】本发明公开了一种园区级综合能源系统辅助设计方法及系统,所述方法包括:获取园区源侧历史数据和荷侧历史数据;对于源侧历史数据中的各类能源,分别针对日变化数据进行聚类分区,并将数据量最大的类簇进行可视化显示,得到各类能源的可用性和供能特性;对于荷侧历史数据,针对日变化数据进行聚类分区,得到反映各类用户类型的类簇,并对这些类簇进行可视化显示,得到各类用户类型的用能特性;基于各类能源的可用性和供电特性,以及各类用户类型的用电特性,为荷侧的各类用户匹配源侧的能源种类和供能方式。本发明能够为能源配置的合理化给出定量的参考依据,保证了后续决策的准确性。 【EN】The invention discloses a park level comprehensive energy system aided design method and a system, wherein the method comprises the following steps: acquiring historical data of a source side and historical data of a load side of a park; for various energy sources in the source side historical data, clustering and partitioning are respectively carried out on day-to-day variation data, and the cluster with the largest data volume is visually displayed, so that the availability and energy supply characteristics of the various energy sources are obtained; for the load side historical data, clustering and partitioning are carried out on daily change data to obtain class clusters reflecting various user types, and the class clusters are visually displayed to obtain energy utilization characteristics of various user types; based on the availability and power supply characteristics of various energy sources and the power utilization characteristics of various user types, the energy source types and the energy supply modes at the source side are matched for various users at the load side. The method can provide quantitative reference basis for rationalization of energy configuration, and ensures accuracy of subsequent decision.
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7:
[发明]
【中文】一种在传感器网络中最优化信息年龄的分布式调度方法 【EN】Distributed scheduling method for optimizing information age in sensor network
申请号:
201911087295.X
公开号:CN110856264A 主分类号:H04W72/12
申请人:
【中文】山东大学【EN】
SHANDONG University
申请日:2019.11.08 公开日:2020.02.28
发明人:
【中文】李峰
;
于东晓
;
段新朋
;
刘政阳【EN】Li Feng
;
Yu Dongxiao
;
Duan Xinpeng
;
Liu Zhengyang
摘要:【中文】本发明属于通信领域,具体涉及一种在传感器网络中最优化传感器节点信息年龄的分布式调度方法。一种在传感器网络中最优化信息年龄的分布式调度方法,包括:同步无线传感器网络,将时间离散化为一系列时隙t=1,2,…,初始化任意传感器节点i的传输概率p
i
;在任意一个时隙t中,每个传感器节点i根据信道侦听情况,根据传输概率随机决定是否进行数据传输,并自适应地调整其数据传输概率。本发明是一种分布式的调度算法,相比于传统的集中式调度方法,不依赖于中心基础设施,且不需要节点间进行信息交换,减小了通信代价,提高了系统的可扩展性和鲁棒性;同时,在恶意信道干扰下,仍能够以常量因子逼近最优峰值信息年龄。 【EN】The invention belongs to the field of communication, and particularly relates to a distributed scheduling method for optimizing information age of a sensor node in a sensor network. A distributed scheduling method for optimizing information age in a sensor network, comprising: the synchronous wireless sensor network disperses time into a series of time slots t 1,2, …, initializes the transmission probability p of any sensor node i
i
(ii) a In any time slot t, each sensor node i randomly determines whether to transmit data according to the channel interception condition and the transmission probability, and adaptively adjusts the data transmission probability. Compared with the traditional centralized scheduling method, the distributed scheduling algorithm does not depend on a central infrastructure, does not need information exchange among nodes, reduces the communication cost and improves the systemSystem scalability and robustness; meanwhile, under the interference of a malicious channel, the optimal peak information age can be approached by a constant factor.
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8:
[发明]
【中文】一种考虑测量误差的二维平面传感器定位方法及系统 【EN】Two-dimensional plane sensor positioning method and system considering measurement error
申请号:
201911095251.1
公开号:CN110856252A 主分类号:H04W64/00
申请人:
【中文】山东大学【EN】
SHANDONG University
申请日:2019.11.11 公开日:2020.02.28
发明人:
【中文】王炳昌
;
王天祥
;
梁勇
;
王峰【EN】Wang Bingchang
;
Wang Tianxiang
;
Liang Yong
;
Wang Feng
摘要:【中文】本公开提供了一种考虑测量误差的二维平面传感器定位方法及系统。其中,考虑测量误差的二维平面传感器定位方法包括在整个二维平面的传感器网络中,选择三个位置已知的节点作为锚节点;利用多维标度法,计算待定位节点相对其所有邻节点的重心坐标;随机给待定位节点一个初始状态,并利用分布式迭代算法,通过有限次迭代计算待定位节点真实坐标的预测值。 【EN】The disclosure provides a two-dimensional plane sensor positioning method and system considering measurement errors. The two-dimensional plane sensor positioning method considering the measurement error comprises the steps of selecting three nodes with known positions as anchor nodes in the whole two-dimensional plane sensor network; calculating the barycentric coordinates of the node to be positioned relative to all adjacent nodes by using a multidimensional scaling method; and randomly giving an initial state to the node to be positioned, and calculating a predicted value of the real coordinate of the node to be positioned through finite iteration by using a distributed iterative algorithm.
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9:
[发明]
【中文】车载式隧道地质素描装置及使用方法 【EN】Vehicle-mounted tunnel geological sketch device and use method
申请号:
201911096841.6
公开号:CN110850435A 主分类号:G01S17/89
申请人:
【中文】山东大学【EN】
SHANDONG University
申请日:2019.11.11 公开日:2020.02.28
发明人:
【中文】许振浩
;
邵瑞琦
;
谢辉辉
;
余腾飞
;
林鹏
;
潘东东【EN】Xu Zhenhao
;
Shao Ruiqi
;
Xie Huihui
;
Yu Tengfei
;
Lin Peng
;
Pan Dongdong
摘要:【中文】本公开提供了一种车载式隧道地质素描装置及使用方法,包括设置于隧道内轨道车上的数据采集单元,包括摄像及扫描设备、激光扫描测距设备和红外热感应扫描设备,摄像及扫描设备设置于轨道车的两侧,被配置为获取隧洞内洞壁图像,单侧的摄像扫描设备覆盖从拱顶中间线至对应一侧的整个侧壁;激光扫描测距设备用于获取其到隧洞壁的距离;红外热感设备用于获取隧洞壁岩层的温度;数据采集单元通过无线传输系统传输至数据分析系统,数据分析系统被配置为依据激光测距设备获得的轨道车至隧洞壁的距离来分析节理位置及大小,塌腔区、掉快区的位置及大小,并提供隧道的整体三维空间图,根据图像特征,利用已训练好的模型来识别隧道内岩性,判定图像中岩层的基本岩性。 【EN】The vehicle-mounted tunnel geological sketch device comprises a data acquisition unit arranged on a railcar in a tunnel, wherein the data acquisition unit comprises a camera and scanning device, a laser scanning distance measuring device and an infrared thermal induction scanning device; the laser scanning distance measuring equipment is used for acquiring the distance from the laser scanning distance measuring equipment to the tunnel wall; the infrared thermal sensing device is used for acquiring the temperature of the rock stratum of the tunnel wall; the data acquisition unit is transmitted to the data analysis system through the wireless transmission system, the data analysis system is configured to analyze the position and the size of a joint, the position and the size of a collapsed cavity area and a falling fast area according to the distance from the rail car to the tunnel wall obtained by the laser ranging device, provide an overall three-dimensional space diagram of the tunnel, recognize the lithology in the tunnel by using a trained model according to the image characteristics, and judge the basic lithology of the rock stratum in the image.
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10:
[发明]
【中文】超前预报底板探测智能雷达搭载系统及探测方法 【EN】Intelligent radar carrying system and method for advanced forecast bottom plate detection
申请号:
201911096851.X
公开号:CN110850398A 主分类号:G01S13/04
申请人:
【中文】山东大学【EN】
SHANDONG University
申请日:2019.11.11 公开日:2020.02.28
发明人:
【中文】许振浩
;
卜泽华
;
黄鑫
;
林鹏
;
王孝特
;
张一驰
;
潘东东【EN】Xu Zhenhao
;
Bu Zehua
;
Huang Xin
;
Lin Peng
;
Wang Xiaote
;
Zhang Yichi
;
Pan Dongdong
摘要:【中文】本公开提出了超前预报底板探测智能雷达搭载系统及探测方法,信号发射和接收系统,信息处理系统,智能测距系统,智能驱动系统以及智能定位系统;所述信号发射和接收系统将探测接收的雷达信息传输至信息处理系统进行处理,处理后得到障碍物底部的探测信息,将探测产生的雷达信号数据和设备本体所在的位置信息一一对应,确保探测区域完整覆盖目标区域。 【EN】The disclosure provides an advanced forecast bottom plate detection intelligent radar carrying system and a detection method, a signal transmitting and receiving system, an information processing system, an intelligent distance measuring system, an intelligent driving system and an intelligent positioning system; the signal transmitting and receiving system transmits the detected and received radar information to the information processing system for processing, the detected information at the bottom of the obstacle is obtained after processing, radar signal data generated by detection correspond to position information of the equipment body one by one, and the target area is completely covered by the detected area.
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