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申请号:201811073171.1 公开号:CN110912819A 主分类号:H04L12/713
摘要:【中文】本发明公开了一种路由收敛的方法及装置,涉及数据通信领域,该方法通过对网络设备预先配置中间系统的虚拟系统ID,并洪泛携带有IS可达性信息的源系统和虚拟系统的LSP分片报文,使得其他网络设备的中间系统接收到携带有IS可达性信息的LSP报文时,可提前触发部分SPF计算并生成SPF树;然后再洪泛封装了链路状态信息的LSP分片报文,此时其他网络设备仅需触发部分路由计算,从而达到路由快速收敛的效果。 【EN】The invention discloses a method and a device for routing convergence, which relate to the field of data communication.A virtual system ID of an intermediate system IS pre-configured for network equipment, and LSP fragmentation messages of a source system and a virtual system carrying IS reachability information are flooded, so that when the intermediate system of other network equipment receives the LSP messages carrying the IS reachability information, partial SPF calculation can be triggered in advance to generate an SPF tree; and then flooding and packaging the LSP fragmentation message of the link state information, and at the moment, other network equipment only needs to trigger part of route calculation, thereby achieving the effect of rapid route convergence.
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申请号:201911300331.6 公开号:CN110996180A 主分类号:H04N21/4788
申请人:【中文】李昱颉【EN】Li Yujia 申请日:2019.12.17 公开日:2020.04.10
摘要:【中文】本发明实施例提供了一种网络直播聊天方法、系统及服务器,方法包括:获取第一用户通过第一客户端发送的第一请求信息,获取与聊天规则对应的等待队列,并将第一请求信息存入等待队列中;从等待队列中选择符合预设规则的、除第一请求信息外的请求信息,从所选择的请求信息中确定第一数量个请求信息,在发送所选择的请求信息的各目标客户端与第一客户端之间建立聊天通道,以使得第一客户端与各目标客户端之间进行信息交互,以及使得第一客户端与各目标客户端的显示界面上均显示聊天窗口;删除等待队列中的第一请求信息以及所选择的各个请求信息。采样本发明实施例提供的方案可以在直播间内与其他观众进行私密沟通。 【EN】The embodiment of the invention provides a network live broadcast chatting method, a system and a server, wherein the method comprises the following steps: acquiring first request information sent by a first user through a first client, acquiring a waiting queue corresponding to a chat rule, and storing the first request information into the waiting queue; selecting request information which accords with a preset rule and is except for the first request information from the waiting queue, determining a first number of request information from the selected request information, and establishing a chat channel between each target client side which sends the selected request information and the first client side so as to enable the first client side and each target client side to carry out information interaction and enable the first client side and each target client side to display a chat window on a display interface; and deleting the first request information and the selected individual request information in the waiting queue. The scheme provided by the embodiment of the invention can be used for carrying out private communication with other audiences in a live broadcast room.
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申请号:201811458441.0 公开号:CN110951689A 主分类号:C12N5/10
摘要:【中文】本发明涉及一种基于CD19和CD30的双重嵌合抗原受体基因修饰的免疫细胞及其应用,所述双重嵌合抗原受体包括嵌合抗原受体CD19和嵌合抗原受体CD30。所述嵌合抗原受体包括抗原结合结构域、跨膜结构域、共刺激信号传导区和CD3ζ信号传导结构域以及可诱导自杀融合结构域串联而成。本发明的嵌合抗原受体能特异性的识别肿瘤表面抗原CD19和CD30,相比于使用其他单一嵌合抗原受体T细胞,联合使用两种抗原靶向CAR‑T细胞针对CD19阴性复发,以及CD19低表达的B细胞肿瘤使得治疗效果更好,更容易让疾病缓解。 【EN】The invention relates to a CD19 and CD 30-based double chimeric antigen receptor gene modified immune cell and application thereof, wherein the double chimeric antigen receptor comprises a chimeric antigen receptor CD19 and a chimeric antigen receptor CD 30. The chimeric antigen receptor comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain, in tandem with an inducible suicide fusion domain. The chimeric antigen receptor can specifically recognize tumor surface antigens CD19 and CD30, and compared with other single chimeric antigen receptor T cells, two antigens are combined to target CAR-T cells to negative relapse of CD19, and B cell tumors with low expression of CD19 have better treatment effect and are easier to relieve diseases.
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申请号:202010032128.1 公开号:CN111122953A 主分类号:G01R19/145
申请人:【中文】李呈昱【EN】Li Chengyu 申请日:2020.01.13 公开日:2020.05.08
摘要:【中文】本发明提供了一种带剥线功能的测电笔,包括测试笔壳体,设置在测试笔壳体上部内侧设置有电池仓,在电池仓的外端面设置有水平推面,沿水平推面向上设置有电池盖组件,所述电池盖组件包括沿水平推面设置在电池仓上的盖体,设置在盖体上的固定块,设置在固定块内的固定槽,在固定槽的内部设置有刀片,且在所述固定块上设置有多个直径逐渐增大的半圆形切口,在半圆形切口处刀片由固定槽凸出,在所述盖体上端还设置有一固定孔,该固定孔与挂扣上设置的固定端固定;所述挂扣刀片平行设置,线缆由半圆形切口穿入,下压挂扣将线缆固定在半圆形切口,在半圆形切口处凸出的刀片即可将线缆切断或者把外表皮切除。 【EN】The invention provides a test pencil with a wire stripping function, which comprises a test pencil shell, wherein a battery bin is arranged on the inner side of the upper part of the test pencil shell, a horizontal push surface is arranged on the outer end surface of the battery bin, a battery cover assembly is upwards arranged along the horizontal push surface, the battery cover assembly comprises a cover body arranged on the battery bin along the horizontal push surface, a fixed block arranged on the cover body, a fixed groove arranged in the fixed block, a blade is arranged inside the fixed groove, a plurality of semicircular notches with gradually increasing diameters are arranged on the fixed block, the blade at the semicircular notches protrudes from the fixed groove, a fixed hole is also arranged at the upper end of the cover body, and the fixed hole is fixed with a fixed end arranged on a hanging buckle; the hanging buckle blades are arranged in parallel, the cable penetrates through the semicircular cut, the hanging buckle is pressed downwards to fix the cable at the semicircular cut, and the blade protruding from the semicircular cut can cut off the cable or cut off the outer skin.
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申请号:201811253062.8 公开号:CN111105058A 主分类号:G06Q10/04
申请人:【中文】阿里巴巴集团控股有限公司【EN】Alibaba Group Holding Ltd. 申请日:2018.10.25 公开日:2020.05.05
摘要:【中文】本发明实施例提供了一种跑步路线的动态估时方法和装置以及电子设备。该方法包括:预先采集用户在跑步状态时的轨迹数据,得到历史跑步轨迹;根据所述历史跑步轨迹,计算得到用户的历史跑步速度;根据所述用户的历史跑步速度,计算得到用户的预估跑步速度;获取用户本次跑步的目标距离,根据所述用户的预估跑步速度和所述目标距离,计算得到本次跑步的预估时长。本发明实施例通过获取用户的历史跑步轨迹来动态估算用户的预估跑步速度,从而计算得到用户本次跑步的预估时长,计算出的预估时长更加符合用户的实际情况,具有更高的准确性。 【EN】The embodiment of the invention provides a running route dynamic time estimation method and device and electronic equipment. The method comprises the following steps: acquiring track data of a user in a running state in advance to obtain a historical running track; calculating to obtain the historical running speed of the user according to the historical running track; calculating to obtain the estimated running speed of the user according to the historical running speed of the user; and obtaining the target distance of the running of the user, and calculating to obtain the estimated time length of the running according to the estimated running speed of the user and the target distance. According to the embodiment of the invention, the estimated running speed of the user is dynamically estimated by acquiring the historical running track of the user, so that the estimated time length of the user running at this time is calculated, the calculated estimated time length is more in line with the actual situation of the user, and the accuracy is higher.
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申请号:202010191399.1 公开号:CN111235032A 主分类号:C12M3/00
摘要:【中文】本发明涉及一种用于干细胞/免疫细胞生产的无菌系统及系统控制方法,属于生物技术领域。本发明解决了现有用于干细胞/免疫细胞生产的无菌系统存在的控制不足,无菌环境能耗过高,设计不合理的问题。本发明包括用于进行干细胞/免疫细胞生产的无菌隔离区;所述无菌隔离区设有操作人员进出的人员通道和产品物料进出的物流通道;所述无菌隔离区的顶部设有设有进气管路机构,所述无菌隔离区的下部设有回气管路;所述进气管路机构包括补气管路,所述补气管路上臭氧产生器和VHP发生器,所述补气管路上连通有风机,所述回气管路连通在补气管路上度。 【EN】The invention relates to a sterile system for stem cell/immune cell production and a system control method, belonging to the technical field of biology. The invention solves the problems of insufficient control, overhigh energy consumption of sterile environment and unreasonable design of the existing sterile system for stem cell/immune cell production. The invention includes sterile isolation zones for stem cell/immune cell production; the sterile isolation area is provided with a personnel channel for the inlet and outlet of operators and a logistics channel for the inlet and outlet of product materials; the top of the sterile isolation area is provided with an air inlet pipeline mechanism, and the lower part of the sterile isolation area is provided with an air return pipeline; the air inlet pipeline mechanism comprises an air supplementing pipeline, an ozone generator and a VHP generator are arranged on the air supplementing pipeline, a fan is communicated with the air supplementing pipeline, and the air returning pipeline is communicated with the air supplementing pipeline.
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申请号:201910994950.3 公开号:CN110840467A 主分类号:A61B5/16
申请人:【中文】天津大学【EN】Tianjin University 申请日:2019.10.18 公开日:2020.02.28
摘要:【中文】本发明公开了一种眼动数据与精神系统疾病的关联分析方法,步骤1:建立健康对照组数据样本;步骤2:通过在多种情境下设定的不同类观看“任务”来获取大量同一测试用户在同等条件下的多样性眼部运动数据;步骤3:利用深度学习分类算法将全部用户眼动数据进行分类归纳,至少包括情境、凝视区域、凝视时间、扫视时间或视线轨迹范围;步骤4:利用智能算法将各情境下的测试用户眼动数据与健康对照组眼动数据比对,输出关于平均凝视时间与扫视时间的差值和占比的文字和图片;步骤5:建立智能扩大健康对照组样本系统。本发明结合与专业人员的合作,一方面保证了符合专业素质的智能分析方法的可行性,另一方面还提高了进行研究的准确性和科学性。 【EN】The invention discloses a correlation analysis method of eye movement data and mental system diseases, which comprises the following steps: establishing a health control group data sample; step 2: acquiring a large amount of diverse eye movement data of the same test user under the same condition by different viewing 'tasks' set under various situations; and step 3: classifying and summarizing all user eye movement data by using a deep learning classification algorithm, wherein the data at least comprises a situation, a staring area, staring time, glance time or a sight line track range; and 4, step 4: comparing the eye movement data of the test user under each situation with the eye movement data of a healthy control group by using an intelligent algorithm, and outputting characters and pictures related to the difference and the proportion of the average staring time and the saccade time; and 5: and establishing an intelligent extended healthy control group sample system. The invention combines the cooperation with professionals, on one hand, the feasibility of the intelligent analysis method which accords with professional qualifications is ensured, and on the other hand, the accuracy and the scientificity of research are also improved.
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申请号:201911184553.6 公开号:CN110846852A 主分类号:D06F35/00
摘要:【中文】本发明提供了一种洗衣机及洗衣机杀菌方法,该洗衣机包括:箱体、控制模块、传感器和若干移动模块;所述箱体,包括:机盖;所述若干移动模块固定在所述箱体的底部;所述传感器设置于所述箱体的顶部和/或侧面,用于获取监控区域内的光照信息,并将所述光照信息发送给所述控制模块;所述控制模块设置于所述箱体上,用于确定所述光照信息是否满足预设的杀菌条件,如果是,根据所述光照信息驱动所述若干移动模块,以使所述箱体移动至目标位置;控制所述机盖开启,以通过光照对所述箱体的内部进行杀菌。该洗衣机能够降低杀菌耗费的电能,避免二次污染。 【EN】The invention provides a washing machine and a washing machine sterilization method, wherein the washing machine comprises: the device comprises a box body, a control module, a sensor and a plurality of mobile modules; the box, include: a machine cover; the plurality of mobile modules are fixed at the bottom of the box body; the sensor is arranged on the top and/or the side of the box body and used for acquiring illumination information in a monitoring area and sending the illumination information to the control module; the control module is arranged on the box body and used for determining whether the illumination information meets a preset sterilization condition, and if so, the control module drives the plurality of mobile modules according to the illumination information to enable the box body to move to a target position; and controlling the cover to be opened so as to sterilize the inside of the box body through illumination. The washing machine can reduce the electric energy consumed by sterilization and avoid secondary pollution.
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申请号:201911205968.7 公开号:CN110871402A 主分类号:B24B37/14
摘要:【中文】本发明公开了一种蓝宝石衬底用减薄砂轮,包括基体;所述基体设有中心孔;所述基体设有第一圈砂轮齿、第二圈砂轮齿、第三圈砂轮齿;所述第一圈砂轮齿位于基体边缘处;所述第二圈砂轮齿位于第一圈砂轮齿与第三圈砂轮齿之间。本发明设计三圈砂轮齿结构,利用空隙作为排屑槽,同时对砂轮齿进行配方设计,提升了磨削产品表面质量,提高良率。 【EN】The invention discloses a thinning grinding wheel for a sapphire substrate, which comprises a base body; the base body is provided with a central hole; the base body is provided with a first ring of grinding wheel teeth, a second ring of grinding wheel teeth and a third ring of grinding wheel teeth; the first ring of grinding gear teeth are positioned at the edge of the base body; and the second circle of grinding wheel teeth are positioned between the first circle of grinding wheel teeth and the third circle of grinding wheel teeth. The grinding wheel tooth structure with three circles is designed, the gaps are used as chip grooves, and meanwhile, the grinding wheel teeth are subjected to formula design, so that the surface quality of a ground product is improved, and the yield is improved.
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申请号:201911135152.1 公开号:CN110935020A 主分类号:A61K41/00
申请人:【中文】同济大学【EN】TONGJI University 申请日:2019.11.19 公开日:2020.03.31
摘要:【中文】本发明涉及一种多功能抗氧化磁性纳米复合材料及其制备方法,纳米复合材料是以水合氯化铁、天然聚合物木质素为原料,采用简便的溶剂热法一步合成的木质素‑铁氧体纳米复合材料。与现有技术相比,本发明制得的纳米复合材料既具有优异的抗氧化性与磁性能,又具有良好的生物相容性,能够将活性自由基清除与基于磁场的物理疗法及磁共振成像等功能结合于一体,使其在氧化应激相关疾病治疗方面具有广阔的应用前景。此外,基于所制备的纳米复合材料的优异的磁驱动性能,其在磁驱动马达及药物精准递送等领域也具有极大的应用潜能。 【EN】The invention relates to a multifunctional antioxidant magnetic nano composite material and a preparation method thereof, wherein the nano composite material is a lignin-ferrite nano composite material which is synthesized by taking ferric chloride hydrate and natural polymer lignin as raw materials in one step by adopting a simple solvothermal method. Compared with the prior art, the nano composite material prepared by the invention has excellent oxidation resistance and magnetic property, has good biocompatibility, can combine the functions of active free radical scavenging, magnetic field-based physiotherapy, magnetic resonance imaging and the like into a whole, and has wide application prospect in the aspect of treating oxidative stress related diseases. In addition, based on the excellent magnetic driving performance of the prepared nano composite material, the nano composite material also has great application potential in the fields of magnetic driving motors, accurate drug delivery and the like.
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