摘要：【中文】本发明公开了一类新型脂质材料，用于实现乳腺癌靶向药物的传递。所述的新型脂质材料以赖氨酸为连接基团，分别与胆甾部分、生物素部分和葡萄糖部分连接。可利用该新型脂质材料中的生物素和葡萄糖分别与乳腺癌细胞表面高表达的生物素转运体（SMVT）和葡萄糖转运体（GLUT1）之间的亲和力，实现对乳腺癌的双重靶向功能，发挥更强的乳腺癌靶向治疗作用。该新型脂质材料可用于脂质体、纳米粒、胶束等在内的不同剂型，所制成的载紫杉醇脂质体具有明显的乳腺癌靶向性，拥有广阔的应用前景。 【EN】The invention discloses a novel lipid material for realizing the delivery of a breast cancer targeted drug. The novel lipid material takes lysine as a connecting group and is respectively connected with a cholesteric part, a biotin part and a glucose part. The affinity between biotin and glucose in the novel lipid material and a biotin transporter (SMVT) and a glucose transporter (GLUT 1) highly expressed on the surface of a breast cancer cell can be utilized to realize the double targeting function of the breast cancer and play a stronger role in targeted therapy of the breast cancer. The novel lipid material can be used for different dosage forms including liposome, nanoparticles, micelle and the like, and the prepared paclitaxel-loaded liposome has obvious breast cancer targeting property and wide application prospect.