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1:
[发明]
【中文】作为诊治帕金森病的分子标志物基因-BLM 【EN】Molecular marker gene-BLM as diagnosis and treatment for Parkinson's disease
申请号:
201911361430.5
公开号:CN110872623A 主分类号:C12Q1/6883
申请人:
【中文】青岛泱深生物医药有限公司【EN】Qingdao Yangshen biomedical Co., Ltd
申请日:2019.12.25 公开日:2020.03.10
发明人:
【中文】董东
;
常鹏
;
王李娜【EN】Dong Dong
;
Chang Peng
;
Wang Lina
摘要:【中文】本发明涉及作为诊治帕金森病的分子标志物基因‑BLM,实验证明在正常对照和帕金森病患者中BLM基因及其表达产物存在差异表达,据此可将BLM基因及其表达产物作为诊断帕金森病的生物标志物。另外,本发明体外细胞实验证明干扰BLM基因表达,可以抑制缓解神经细胞损伤,据此可以开发治疗帕金森病的药物。 【EN】The invention relates to a molecular marker gene-BLM for diagnosing and treating Parkinson's disease, which can be used as a biomarker for diagnosing the Parkinson's disease by using the BLM gene and an expression product thereof in normal control and Parkinson's disease patients through experimental verification that the BLM gene and the expression product thereof are differentially expressed. In addition, in vitro cell experiments prove that the interference of BLM gene expression can inhibit and relieve nerve cell damage, so that the medicine for treating the Parkinson disease can be developed.
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2:
[发明]
【中文】检测WAS基因的试剂、产品以及WAS基因的用途 【EN】Reagent and product for detecting WAS gene and application of WAS gene
申请号:
201911361414.6
公开号:CN110938686A 主分类号:C12Q1/6883
申请人:
【中文】青岛泱深生物医药有限公司【EN】Qingdao Yangshen biomedical Co., Ltd
申请日:2019.12.25 公开日:2020.03.31
发明人:
【中文】董东
;
常鹏
;
王李娜【EN】Dong Dong
;
Chang Peng
;
Wang Lina
摘要:【中文】本发明公开了检测WAS基因的试剂、产品以及WAS基因的用途。本发明发现帕金森病患者WAS基因表达异常,据此可将WAS用于开发诊断帕金森病的试剂、产品以及治疗帕金森病的药物。本发明的研究成果为临床医师制定个性化治疗方案提供理论基础、并且能够为帕金森病药物的开发提供新的药物靶点。 【EN】The invention discloses a reagent and a product for detecting WAS gene and application of the WAS gene. The invention discovers WAS gene expression abnormity of Parkinson disease patients, and therefore, the WAS can be used for developing reagents and products for diagnosing the Parkinson disease and medicines for treating the Parkinson disease. The research result of the invention provides theoretical basis for the clinician to formulate a personalized treatment scheme and can provide a new drug target for the development of the Parkinson disease drug.
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3:
[发明]
【中文】TKT在诊治帕金森病中的用途 【EN】Application of TKT in diagnosis and treatment of Parkinson disease
申请号:
201911359661.2
公开号:CN110982892A 主分类号:C12Q1/6883
申请人:
【中文】青岛泱深生物医药有限公司【EN】Qingdao Yangshen biomedical Co., Ltd
申请日:2019.12.25 公开日:2020.04.10
发明人:
【中文】董东
;
常鹏
;
王李娜【EN】Dong Dong
;
Chang Peng
;
Wang Lina
摘要:【中文】本发明属于生物医学诊断领域,特别涉及TKT在诊治帕金森病中的用途。本发明还提供了帕金森病早期诊断标志物的检测方法。本发明利用QPCR技术从血液样本中检测出TKT,对帕金森病患者的早期诊断提供了新的途径和方法,弥补了传统诊断方法的不足,可望提高帕金森病早期诊断水平,从而有助于改善帕金森病患者的预后。 【EN】The invention belongs to the field of biomedical diagnosis, and particularly relates to application of TKT in diagnosis and treatment of Parkinson's disease. The invention also provides a detection method of the early diagnosis marker of the Parkinson disease. The invention detects TKT from the blood sample by utilizing QPCR technology, provides a new way and method for early diagnosis of the Parkinson disease patient, makes up the defects of the traditional diagnosis method, and is expected to improve the early diagnosis level of the Parkinson disease, thereby being beneficial to improving the prognosis of the Parkinson disease patient.
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4:
[发明]
【中文】一种SQL指令生成方法及系统 【EN】SQL instruction generation method and system
申请号:
201910959039.9
公开号:CN110866028A 主分类号:G06F16/242
申请人:
【中文】微梦创科网络科技(中国)有限公司【EN】Weimengchuangke Network Technology (China) Co., Ltd.
申请日:2019.10.10 公开日:2020.03.06
发明人:
【中文】刘邦
;
彭冬【EN】Liu Bang
;
Peng Dong
摘要:【中文】本发明实施例提供一种SQL指令生成方法及系统,所述方法包括:接收查询指令,对查询指令解析得到输入指令和输出指令;按序逐行解析输入指令,针对每一行输入指令:按照该行指令中设定的分割关键字确定指令中的资源类型,根据资源类型调用对应的处理引擎,基于调用的处理引擎从对应数据库中获取相应的数据信息,并保存在相应的数据集合中;在各行输入指令处理完毕后,解析输出指令,合并各数据集合中的数据信息并输出。本技术方案提供了一套通用且规范的SQL指令生成语言格式,可以有效查询常见的数据存储服务,并对结果集进行归并后返回。 【EN】The embodiment of the invention provides a method and a system for generating an SQL instruction, wherein the method comprises the following steps: receiving a query instruction, and analyzing the query instruction to obtain an input instruction and an output instruction; analyzing the input instructions line by line in sequence, and aiming at each line, inputting the instructions: determining the resource type in the instruction according to the partition keywords set in the row of instructions, calling the corresponding processing engine according to the resource type, acquiring corresponding data information from the corresponding database based on the called processing engine, and storing the corresponding data information in the corresponding data set; and after the input instructions of all rows are processed, analyzing the output instructions, combining the data information in all the data sets and outputting the data information. The technical scheme provides a set of universal and standard SQL instruction generation language format, common data storage service can be effectively inquired, and the result set is returned after being merged.
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5:
[发明]
【中文】一种基于Go语言的分布式锁的加锁与释放锁的方法及系统 【EN】Go language based locking and releasing method and system for distributed lock
申请号:
201910983238.3
公开号:CN110866021A 主分类号:G06F16/23
申请人:
【中文】微梦创科网络科技(中国)有限公司【EN】Weimengchuangke Network Technology (China) Co., Ltd.
申请日:2019.10.16 公开日:2020.03.06
发明人:
【中文】唐俊
;
彭冬【EN】Tang Jun
;
Peng Dong
摘要:【中文】本发明实施例提供一种基于Go语言的分布式锁的加锁与释放锁的方法及系统,所述加锁方法包括:接收加锁请求,在判定加锁请求的来源IP为白名单IP并且加锁请求的参数为合法的情况下,根据加锁请求,确定加锁请求对应的要锁定的资源所在的区域;对确定的区域加互斥锁;根据加锁请求,查找区域中加锁请求对应的要锁定的资源是否已存在锁;若锁已存在,则判断锁是否过期;当判定资源不存在锁或者存在锁且锁过期的情况下,为资源保存加锁请求对应的锁信息;释放区域的互斥锁并返回加锁成功消息。本技术方案通过基于Go语言的分布式锁的方案,功能职责清晰单一,出错更易定位并极大的降低了接入成本。 【EN】The embodiment of the invention provides a locking and lock releasing method and a system of a distributed lock based on Go language, wherein the locking method comprises the following steps: receiving a locking request, and determining an area where a resource to be locked corresponding to the locking request is located according to the locking request under the condition that the source IP of the locking request is judged to be a white list IP and the parameter of the locking request is judged to be legal; adding a mutual exclusion lock to the determined area; according to the locking request, searching whether the resource to be locked corresponding to the locking request in the area has a lock; if the lock exists, judging whether the lock is overdue; when the resource is judged to have no lock or to have a lock and the lock is overdue, storing the lock information corresponding to the locking request for the resource; and releasing the mutual exclusion lock of the area and returning a locking success message. According to the technical scheme, through the distributed lock scheme based on the Go language, the function responsibility is clear and single, errors are easier to locate, and the access cost is greatly reduced.
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6:
[发明]
【中文】回流焊炉的降温系统 【EN】Cooling system of reflow oven
申请号:
201810993604.9
公开号:CN110871299A 主分类号:B23K3/00
申请人:
【中文】伊利诺斯工具制品有限公司【EN】ILLINOIS TOOL WORKS Inc.
申请日:2018.08.29 公开日:2020.03.10
发明人:
【中文】闫升虎
;
舒鹏
;
张冬【EN】Yan Shenghu
;
Shu Peng
;
Zhang Dong
摘要:【中文】本申请公开一种回流焊炉的降温系统,回流焊炉包括加热区,降温系统用于调节加热区的温度,降温系统包括:至少一个进气口和至少一个排气口,至少一个进气口和至少一个排气口设置在加热区上;送风装置;至少一个进气管道,至少一个进气管道的入口与送风装置连接,至少一个进气管道的出口与至少一个进气口连接,至少一个进气管道能够可控地将送风装置与至少一个进气口流体连通;和至少一个排气管道,至少一个排气管道的入口与至少一个排气口连接,至少一个排气管道的出口与外界连接,至少一个排气管道能够可控地将至少一个排气口与外界流体连通。本申请的降温系统能够缩短回流焊炉从较高加热温度到较低加热温度的转换时间。 【EN】The application discloses cooling system of reflow oven, reflow oven include the zone of heating, and cooling system is used for adjusting the temperature in the zone of heating, and cooling system includes: at least one inlet port and at least one outlet port disposed on the heating zone; an air supply device; the inlet of the at least one air inlet pipeline is connected with the air supply device, the outlet of the at least one air inlet pipeline is connected with the at least one air inlet, and the at least one air inlet pipeline can controllably enable the air supply device to be in fluid communication with the at least one air inlet; and the inlet of the at least one exhaust pipeline is connected with the at least one exhaust port, the outlet of the at least one exhaust pipeline is connected with the outside, and the at least one exhaust pipeline can controllably communicate the at least one exhaust port with the outside in a fluid mode. The cooling system of this application can shorten reflow oven from higher heating temperature to lower heating temperature's transition time.
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7:
[发明]
【中文】用于回流焊炉的气体控制系统和方法 【EN】Gas control system and method for reflow oven
申请号:
201811013268.3
公开号:CN110874106A 主分类号:G05D27/02
申请人:
【中文】伊利诺斯工具制品有限公司【EN】ILLINOIS TOOL WORKS Inc.
申请日:2018.08.31 公开日:2020.03.10
发明人:
【中文】闫升虎
;
舒鹏
;
张冬【EN】Yan Shenghu
;
Shu Peng
;
Zhang Dong
摘要:【中文】本申请涉及一种用于回流焊炉的气体控制系统和方法,包括:氧气探测装置,能够与炉膛中的气体接触,用于探测炉膛中的氧气浓度;进气阀装置,用于可控地将工作气体源与炉膛流体连通,从而将工作气体输入到炉膛中;以及控制器,根据氧气浓度信号来控制至少一个进气阀装置的开度,以调节输入炉膛中的工作气体。本申请的气体控制系统和方法,实时探测炉膛中的氧气浓度,并根据预先设置的设定值或目标值,自动调节气体控制阀以控制工作气体的输入,控制精度较高,调节速度较快,并且在停止工作或在工作间歇时,能够及时关闭气体控制阀,从而避免浪费、降低成本。 【EN】The present application relates to a gas control system and method for a reflow oven, comprising: the oxygen detection device can be contacted with gas in the hearth and is used for detecting the oxygen concentration in the hearth; an air inlet valve arrangement for controllably fluidly communicating a source of working gas with the furnace for feeding the working gas into the furnace; and a controller for controlling the opening of the at least one air inlet valve device according to the oxygen concentration signal to adjust the working gas input into the furnace. The gas control system and the method have the advantages that the oxygen concentration in the hearth is detected in real time, the gas control valve is automatically adjusted to control the input of working gas according to the preset set value or the target value, the control precision is high, the adjusting speed is high, the gas control valve can be closed in time when the gas control system stops working or works intermittently, and therefore waste and cost reduction are avoided.
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8:
[发明]
【中文】一种环保型智能化建筑用线缆 【EN】Environment-friendly intelligent cable for building
申请号:
201911306238.6
公开号:CN110931158A 主分类号:H01B7/40
申请人:
【中文】中山市标致电子科技有限公司【EN】Zhongshan Peugeot Electronic Technology Co., Ltd.
申请日:2019.12.18 公开日:2020.03.27
发明人:
【中文】齐伟
;
董彭
;
李文勇【EN】Qi Wei
;
Dong Peng
;
Li Wenyong
摘要:【中文】一种环保型智能化建筑用线缆,线缆主体两端均设置有防水连接环;第一连接套上设置有密封凸起和第一磁铁;第二连接套上设置有与密封凸起密封连接的接线凹槽和与第一磁铁相互吸引的第二磁铁;密封凸起上设置有导电体;安装机构包括下套体、上套体和安装环;下套体连接在线缆主体外周;上套体连接在下套体上;安装环设置在上套体上;线芯设置在线缆主体中心,线芯外周设置有绕包防护层;绝缘层设置在绕包防护层外部;阻燃层设置在绝缘层外部;加强层设置在阻燃层外部,加强层外部设置有防水层。本发明线缆连接方便且连接效果好,可有效防止雨水侵湿,安装机构便于对线缆进行安装布线,防止线缆晃动以提高其稳定性,确保安全性能。 【EN】An environment-friendly intelligent cable for buildings is provided, wherein two ends of a cable main body are provided with waterproof connecting rings; the first connecting sleeve is provided with a sealing bulge and a first magnet; the second connecting sleeve is provided with a wiring groove which is hermetically connected with the sealing bulge and a second magnet which is mutually attracted with the first magnet; the sealing bulge is provided with a conductor; the mounting mechanism comprises a lower sleeve body, an upper sleeve body and a mounting ring; the lower sleeve body is connected to the periphery of the cable main body; the upper sleeve body is connected with the lower sleeve body; the mounting ring is arranged on the upper sleeve body; the cable core is arranged in the center of the cable main body, and a wrapping protective layer is arranged on the periphery of the cable core; the insulating layer is arranged outside the wrapping protective layer; the flame-retardant layer is arranged outside the insulating layer; the enhancement layer sets up in fire-retardant layer outside, and the enhancement layer outside is provided with the waterproof layer. The cable is convenient to connect and good in connecting effect, rainwater can be effectively prevented from invading, the installation mechanism is convenient to install and wire the cable, the cable is prevented from shaking to improve the stability of the cable, and the safety performance is ensured.
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9:
[发明]
【中文】一种大功率燃料电池用曝气增湿装置 【EN】Aeration humidifying device for high-power fuel cell
申请号:
201911367691.8
公开号:CN110911713A 主分类号:H01M8/04089
申请人:
【中文】大连锐格新能源科技有限公司【EN】Dalian sharp Amperex Technology Limited
申请日:2019.12.26 公开日:2020.03.24
发明人:
【中文】高鹏
;
董义文【EN】Gao Peng
;
Dong Yiwen
摘要:【中文】本发明涉及一种大功率燃料电池曝气增湿装置,属于燃料电池领域。主要技术方案如下:一种大功率燃料电池曝气增湿装置,包括密闭容器、排水管、循环水泵、电加热器、温度控制器、逆止阀、出气管;所述的密闭容器内自上而下设置淋水器、上部填料、下部填料、曝气装置,所述的下部填料和曝气装置置于去离子水中,所述的曝气装置连接进气管,密闭容器的下方连接补水控制阀、循环水泵和排水管,所述的密闭容器、循环水泵、电加热器、逆止阀依次连接形成回路,所述密闭容器的上方连接出气管。本发明可将反应气快速达到要求的温度和湿度,利用常规器件构造曝气增湿装置,经济性良好。 【EN】The invention relates to an aeration humidifying device of a high-power fuel cell, belonging to the field of fuel cells. The main technical scheme is as follows: a high-power fuel cell aeration humidifying device comprises a closed container, a drain pipe, a circulating water pump, an electric heater, a temperature controller, a check valve and an air outlet pipe; the device is characterized in that a water sprayer, an upper filler, a lower filler and an aeration device are arranged in the closed container from top to bottom, the lower filler and the aeration device are placed in deionized water, the aeration device is connected with an air inlet pipe, a water replenishing control valve, a circulating water pump and a water drain pipe are connected below the closed container, the circulating water pump, an electric heater and a check valve are sequentially connected to form a loop, and an air outlet pipe is connected above the closed container. The invention can make the reaction gas reach the required temperature and humidity quickly, and the aeration humidifying device is constructed by utilizing the conventional devices, thus having good economical efficiency.
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10:
[发明]
【中文】整体式新风除湿机 【EN】Integral fresh air dehumidifier
申请号:
201911412579.1
公开号:CN110940003A 主分类号:F24F3/14
申请人:
【中文】无锡莱多鑫科技有限公司【EN】Wuxi laiduoxin Technology Co., Ltd
申请日:2019.12.31 公开日:2020.03.31
发明人:
【中文】邱东
;
彭利平【EN】Qiu Dong
;
Peng Liping
摘要:【中文】整体式新风除湿机,其可降低除湿蒸发器、除湿冷凝器的除湿载重负荷及功耗,其包括至少两种工作模式:新风模式、除湿模式,当处于新风模式时,风道包括新风送风系统、新风排风系统,新风送风系统、新风排风系统之间设置有竖隔板,竖隔板中部设置有第一风门放置孔,第一风门放置孔内安装有风门,新风系统内设置有与竖隔板垂直的横隔板,横隔板中部设置有第二风门放置孔,风门旋转安装于竖隔板中部延长线与横隔板中部延长线的交点上,风门旋转状态包括竖直状态、水平状态,当风门呈水平状态时,将风道分隔为相互隔绝的外循环系统、除湿系统,外循序系统与室外连通,除湿系统与室内连通,除湿系统内布置有除湿冷凝器、除湿蒸发器。 【EN】Integral new trend dehumidifier, it can reduce dehumidification load and the consumption of dehumidification evaporimeter, dehumidification condenser, and it includes two kinds of mode at least: fresh air mode, the dehumidification mode, when being in the fresh air mode, the wind channel includes fresh air supply system, fresh air exhaust system, fresh air supply system, be provided with perpendicular baffle between the fresh air exhaust system, it is provided with first air door and places the hole to erect the baffle middle part, the downthehole air door of installing is placed to first air door, be provided with in the fresh air system and erect baffle vertically cross slab, the cross slab middle part is provided with the second air door and places the hole, the air door is rotatory to be installed on the nodical of erecting baffle middle part extension line and cross slab middle part extension line, the air door rotation state includes vertical state, the horizontality, when the air door is the horizontality, separate the wind channel for mutual isolated outer circulation system, the dehumidification system, outer system and outdoor intercommunication in proper order, dehumidification system and indoor intercommunication, the dehumidification.
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