摘要：【中文】本发明公开了一种用于感冒的维C银翘片，由如下重量份原料制成：山银花110‑220份、连翘110‑220份、荆芥44‑88份、淡豆豉55‑110份、淡竹叶44‑88份、芦根66‑132份、桔梗66‑132份、甘草55‑110份、牛蒡子66‑132份、对乙酰氨基酚64‑128份、马来酸氯苯那敏1‑2份、薄荷油1‑2份、维生素C 31‑32份,在制备维C银翘片的过程中使用了一种高效压片机，该高效压片机未使用上压轮和下压轮挤压上冲杆和下冲杆的方式进行压片，减少了设备之间的摩擦，增加了设备使用寿命，并在片芯收集前将片芯表面的粉末进行处理，不需要对片芯再次进行表面处理，即可直接包衣，进一步提升了维C银翘片的制备效率。 【EN】The invention discloses a vitamin C Yinqiao tablet for treating cold, which is prepared from the following raw materials in parts by weight: 220 parts of lonicera confusa, 220 parts of forsythia fruit, 44-88 parts of schizonepeta, 55-110 parts of fermented soybean, 44-88 parts of lophatherum gracile, 66-132 parts of reed rhizome, 66-132 parts of platycodon grandiflorum, 55-110 parts of liquorice, 66-132 parts of burdock, 64-128 parts of acetaminophen, 1-2 parts of chlorphenamine maleate, 1-2 parts of peppermint oil and 31-32 parts of vitamin C, a high-efficiency tablet press is used in the process of preparing the vitamin C Yinqiao tablet, the high-efficiency tablet press does not use the mode that the upper pinch roller and the lower pinch roller extrude the upper punch rod and the lower punch rod to carry out tablet pressing, reduces the friction between devices, prolongs the service life of the devices, and the powder on the surface of the tablet core is processed before the tablet core is collected, the tablet core does not need to be subjected to surface treatment again, and the tablet core can be directly coated, so that the preparation efficiency of the vitamin C Yinqiao tablet is further improved.

摘要：【中文】本发明公开了一种具有清热解表的感冒清热颗粒的制备工艺，具体制备过程如下：取荆芥穗、薄荷、紫苏叶提取挥发油，蒸馏后的水溶液另器收集；将提取后的药渣与防风、柴胡、葛根、桔梗、苦杏仁、白芷、苦地丁、芦根加水煎煮两次，然后过滤，并将滤液与第一步中的水溶液合并浓缩成清膏；将制备的清膏中加入适量蔗糖、糊精和乙醇，制成颗粒，然后进行包装封袋。本发明通过上料填充装袋装置进行装袋后封装，通过提升上料机构将制备的颗粒从底部提升传送至填充封袋机构中，然后进行封袋，提升上料机构的设置能够实现在低处进行加料后在物料自动传输至高处进行填充，实现自动化提升加料过程，提高了加工效率。 【EN】The invention discloses a preparation process of cold heat-clearing granules with the functions of clearing heat and relieving exterior syndrome, which comprises the following specific preparation processes: extracting volatile oil from herba Schizonepetae, herba Menthae and folium Perillae, and collecting distilled water solution in another container; decocting the extracted residue, radix Saposhnikoviae, bupleuri radix, radix Puerariae, radix Platycodi, semen Armeniacae amarum, radix Angelicae Dahuricae, herba corydalis Bungeanae, and rhizoma Phragmitis in water twice, filtering, mixing the filtrate with the water solution in the first step, and concentrating to obtain fluid extract; adding appropriate amount of sucrose, dextrin and ethanol into the fluid extract, granulating, packaging, and sealing. According to the automatic material filling and bagging device, bagging and packaging are carried out through the feeding, filling and bagging device, prepared particles are lifted and conveyed into the filling and bag sealing mechanism from the bottom through the lifting and feeding mechanism, and then bag sealing is carried out, and the lifting and feeding mechanism can realize automatic material conveying and filling at a high position after feeding at a low position, so that the automatic material lifting and feeding process is realized, and the processing efficiency is improved.

摘要：【中文】本发明公开了一种基于温度变化趋势判断风电机组主轴轴承健康状况的方法，判断规定时间内两个主轴轴承的温度变化趋势，若该段时间内两个主轴轴承温度的变化趋势不一致，则将该段时间的结果记为1，表明主轴轴承可能存在异常，若两个主轴轴承温度变化趋势一致，则将该段时间变化趋势计为0，表明主轴轴承不存在异常，通过对两个主轴轴承温度变化趋势的连续监测，当主轴轴承在一个长的时间周期内出现多次温度变化趋势不一致的情况时，则认定主轴轴承健康状况出现异常，应安排停机检查并缩短主轴轴承的维护周期，以延长主轴轴承的使用寿命。本发明可以准确判断主轴轴承健康状况，发现主轴轴承的早期故障，利于延长主轴轴承的使用寿命。 【EN】The invention discloses a method for judging the health condition of a main shaft bearing of a wind turbine generator based on temperature change trends, which comprises the steps of judging the temperature change trends of two main shaft bearings in a set time, recording the result of the time as 1 if the temperature change trends of the two main shaft bearings in the time are inconsistent, indicating that the main shaft bearings are possibly abnormal, recording the time change trend as 0 if the temperature change trends of the two main shaft bearings are consistent, indicating that the main shaft bearings are not abnormal, and determining that the health condition of the main shaft bearings is abnormal when the main shaft bearings have the condition of multiple inconsistent temperature change trends in a long time period through continuous monitoring of the temperature change trends of the two main shaft bearings, wherein shutdown inspection is required to be arranged, the maintenance cycle of the main shaft bearings is shortened, and the service life of the main shaft bearings is prolonged. The invention can accurately judge the health condition of the main shaft bearing, discover the early fault of the main shaft bearing and is beneficial to prolonging the service life of the main shaft bearing.

摘要：【中文】本发明提供一种组织工程皮肤支架材料，所述组织工程皮肤支架材料由透明质酸支架和纳米纤维膜组成；所述透明质酸支架由超氧化物歧化酶脂质体负载于透明质酸多孔支架上制得；所述纳米纤维膜由壳聚糖/角蛋白混合溶液制得。本发明还提供组织工程皮肤支架材料的制备方法，采用静电纺丝技术与冷冻干燥技术结合的方法制备的双层皮肤支架材料，解决了皮肤支架材料的生物相容性差和孔径大小不合适的问题以及创面皮肤受有害代谢物影响的问题，且制备方法简单，绿色环保。 【EN】The invention provides a tissue engineering skin scaffold material, which consists of a hyaluronic acid scaffold and a nanofiber membrane; the hyaluronic acid scaffold is prepared by loading superoxide dismutase liposome on a hyaluronic acid porous scaffold; the nanofiber membrane is prepared from a chitosan/keratin mixed solution. The invention also provides a preparation method of the tissue engineering skin scaffold material, the double-layer skin scaffold material prepared by adopting the method of combining the electrostatic spinning technology and the freeze drying technology solves the problems of poor biocompatibility and improper pore size of the skin scaffold material and the problem that wound skin is influenced by harmful metabolites, and the preparation method is simple, green and environment-friendly.

摘要：【中文】本发明公开了一种抗菌型胶原基骨修复材料，包括氧化锌/羟基磷灰石晶须、Ⅰ型胶原、聚乙烯醇、交联剂构成的骨修复材料主体以及氧化石墨烯、聚多巴胺、掺杂磺基水杨酸的聚吡咯自组装层和固载于自组装层的骨形态发生蛋白‑2。本发明材料表面及内部均具有良好的抗菌功效，能够最大程度避免骨移植过程中的炎症、感染，所用原料均无毒无害，具有良好的生物相容性，材料的降解速度与骨缺损修复速度相对一致，通过在骨修复材料表面自组装聚吡咯‑聚多巴胺涂层，能够牢固负载骨形态发生蛋白‑2和稳定释放，提高了骨形态发生蛋白‑2的利用率，同时也极大地避免骨形态发生蛋白‑2浓度过高引发的并发症。 【EN】The invention discloses an antibacterial collagen-based bone repair material which comprises a bone repair material main body, a graphene oxide, polydopamine, a polypyrrole self-assembly layer doped with sulfosalicylic acid and bone morphogenetic protein-2 fixedly carried in the self-assembly layer, wherein the bone repair material main body is composed of zinc oxide/hydroxyapatite whiskers, type I collagen, polyvinyl alcohol and a cross-linking agent. The surface and the interior of the material have good antibacterial effect, inflammation and infection in the bone grafting process can be avoided to the maximum extent, the used raw materials are nontoxic and harmless, the material has good biocompatibility, the degradation speed of the material is relatively consistent with the bone defect repair speed, the polypyrrole-polydopamine coating is self-assembled on the surface of the bone repair material, the bone morphogenetic protein-2 can be firmly loaded and stably released, the utilization rate of the bone morphogenetic protein-2 is improved, and complications caused by overhigh concentration of the bone morphogenetic protein-2 are greatly avoided.

摘要：【中文】本发明公开了一种含蛋白质胶原基骨修复材料，包括介孔羟基磷灰石、改性麦饭石、聚乳酸乙醇酸共聚物、Ⅰ型胶原构成的骨修复材料主体以及氧化石墨烯‑聚吡咯自组装层和固载于自组装层的骨形态发生蛋白‑2。本发明所用原料均无毒无害，具有良好的生物相容性，机械性能优异，材料的降解速度与骨缺损修复速度相对一致，具有较强的成骨活性，形成了骨形态发生蛋白‑2可控释放体系，不会发生突释或无法释放的情况，提高了骨形态发生蛋白‑2的利用率，同时也极大地避免骨形态发生蛋白‑2浓度过高引发的并发症。 【EN】The invention discloses a collagen-based bone repair material containing protein, which comprises a bone repair material main body consisting of mesoporous hydroxyapatite, modified medical stone, polylactic acid-glycolic acid copolymer and collagen I, a graphene oxide-polypyrrole self-assembly layer and bone morphogenetic protein-2 immobilized on the self-assembly layer. The raw materials used in the invention are nontoxic and harmless, have good biocompatibility and excellent mechanical property, the degradation speed of the materials is relatively consistent with the bone defect repair speed, and the materials have strong osteogenic activity, form a bone morphogenetic protein-2 controllable release system, do not generate the condition of burst release or incapability of release, improve the utilization rate of the bone morphogenetic protein-2, and simultaneously greatly avoid complications caused by overhigh concentration of the bone morphogenetic protein-2.

摘要：【中文】本发明公开了一种抗感染组织工程皮肤支架，支架为上下双层结构，层间通过戊二醛交联作用结合在一起，具有良好的机械强度。上层表皮支架聚己内酯‑聚乙二醇‑聚己内酯/纳米银/壳聚糖纳米纱层中纤维内部的纳米银与纤维表面的壳聚糖协同发挥抗菌功效，下层真皮支架丝素/透明质酸纤维中均匀分布有乙酸锌，能够抑制细菌聚集，发挥抗感染功效；下层为纳米纤维束编织支架，纤维束支架的结构、孔径大小及孔隙率可以通过编制自由调节，能够制备得到纤维束有序规则排列、孔径平均值与细胞尺寸接近的支架，使细胞能够进入，并引导组织定向生长。 【EN】The invention discloses an anti-infection tissue engineering skin scaffold, which is of an upper-lower double-layer structure, and layers are combined together through glutaraldehyde crosslinking, so that the scaffold has good mechanical strength. The nano silver inside the fiber in the upper-layer dermal scaffold polycaprolactone-polyethylene glycol-polycaprolactone/nano silver/chitosan nano yarn layer and the chitosan on the surface of the fiber cooperatively play an antibacterial role, and the zinc acetate is uniformly distributed in the lower-layer dermal scaffold fibroin/hyaluronic acid fiber, so that the bacterial aggregation can be inhibited, and the anti-infection function is played; the lower layer is a nano fiber bundle woven support, the structure, the pore size and the porosity of the fiber bundle support can be freely adjusted through weaving, and the support with orderly and regular arrangement of fiber bundles and the average pore size close to the cell size can be prepared, so that cells can enter and direct the tissue to grow directionally.

摘要：【中文】本发明提供一种抗炎抗菌复合皮肤支架材料，所述复合皮肤支架材料由透明质酸真皮层支架和聚己内酯表皮层支架组成；所述复合皮肤支架上负载有海藻酸钠凝胶微球，所述海藻酸钠凝胶微球包含有超氧化物歧化酶及没食子酸；所述透明质酸支架上络合有铜离子、锌离子；本发明采用两次冷冻干燥技术将透明质酸支架和聚己内酯支架结合得到复合皮肤支架材料，解决了创面皮肤易感染、发炎及产生瘢痕问题以及支架材料粘附性弱的问题，并且该皮肤支架材料不仅具有良好的生物相容性和粘附性，且机械性能好，无机体排异性，均可生物降解，降解的产物对生物组织没有毒性也没有异常反应，制备方法简单，绿色环保。 【EN】The invention provides an anti-inflammatory and antibacterial composite skin scaffold material, which consists of a hyaluronic acid dermal layer scaffold and a polycaprolactone epidermal layer scaffold; the composite skin stent is loaded with sodium alginate gel microspheres, and the sodium alginate gel microspheres contain superoxide dismutase and gallic acid; copper ions and zinc ions are complexed on the hyaluronic acid stent; the hyaluronic acid scaffold and the polycaprolactone scaffold are combined by adopting a freeze drying technology twice to obtain the composite skin scaffold material, so that the problems of wound skin infection, inflammation and scar generation and weak scaffold material adhesion are solved, the skin scaffold material has good biocompatibility and adhesion, good mechanical property and inorganic body rejection, and can be biodegraded, the degraded product has no toxicity or abnormal reaction to biological tissues, the preparation method is simple, and the composite skin scaffold material is green and environment-friendly.

摘要：【中文】本发明公开了一种可完全降解组织工程皮肤支架材料，包括细菌纤维素/壳聚糖纳米纤维层和大孔径阵列微米纤维支架两部分，细菌纤维素/壳聚糖纳米纤维层为上层，大孔径阵列微米纤维支架上方为下层，层间通过戊二醛交联结合；所述细菌纤维素/壳聚糖纳米纤维层由木葡糖酸醋杆菌原位合成，表面固定有纤维素酶；所述大孔径阵列微米纤维支架为静电纺乳酸/透明质酸/丝素微纳米纤维有序排列的支架，表面修饰有聚乳酸‑羟基乙酸生长因子缓释微球。本发明所用原料均无毒无害，纤维性质稳定，具有良好的生物相容性，能够在体内完全降解，下层支架的孔隙直径与细胞尺寸接近，使细胞能够进入，还能稳定释放生长因子，有利于皮肤组织再生。 【EN】The invention discloses a completely degradable tissue engineering skin scaffold material, which comprises a bacterial cellulose/chitosan nano fiber layer and a large-aperture array micrometer fiber scaffold, wherein the bacterial cellulose/chitosan nano fiber layer is an upper layer, a lower layer is arranged above the large-aperture array micrometer fiber scaffold, and the layers are combined by glutaraldehyde through crosslinking; the bacterial cellulose/chitosan nanofiber layer is synthesized in situ by gluconacetobacter xylinus, and cellulase is fixed on the surface of the bacterial cellulose/chitosan nanofiber layer; the large-aperture array micro-fiber scaffold is a scaffold with orderly arranged electrospun lactic acid/hyaluronic acid/fibroin micro-nano fibers, and polylactic acid-glycolic acid growth factor sustained-release microspheres are modified on the surface. The raw materials used in the invention are nontoxic and harmless, the fiber property is stable, the biocompatibility is good, the fiber can be completely degraded in vivo, the pore diameter of the lower layer bracket is close to the cell size, the cell can enter, the growth factor can be stably released, and the regeneration of skin tissues is facilitated.

摘要：【中文】本发明提供一种可吸收防黏连敷料，所述可吸收防黏连敷料从贴近皮肤侧起依次为疏水层、亲水层及保护层，所述疏水层为负载微球的聚己内酯/壳聚糖多孔薄膜，所述亲水层的材料为透明质酸、明胶、海藻酸钠或角蛋白中的一种或多种，所述保护层为蛋壳膜与改性聚氨酯薄膜复合而成，本发明还提供了可吸收防黏连敷料的制备方法，制得的可吸收防黏连敷料可降解吸收，不需频繁更换，保持了利于创口修复的湿润环境，力学性能优，抗菌作用强，可促进药物的单向吸收，提高敷料的利用率，且更换敷料时也不会出现黏连创面的问题，防止了二次损伤。 【EN】The invention provides an absorbable anti-adhesion dressing which sequentially comprises a hydrophobic layer, a hydrophilic layer and a protective layer from the side close to the skin, wherein the hydrophobic layer is a polycaprolactone/chitosan porous film loaded with microspheres, the hydrophilic layer is made of one or more of hyaluronic acid, gelatin, sodium alginate or keratin, and the protective layer is formed by compounding an eggshell film and a modified polyurethane film.