摘要：【中文】本发明公开了一种具有生物硫醇检测功能的苯并噻唑类生物硫醇探针，如式(I)所示：中，R为氢、烷基或烷氧基。本发明的探针荧光性能好，合成简单，与硫醇反应后，探针荧光显著增强，并对硫醇表现出很好的选择性，可以作为生物硫醇荧光探针。此外，制备该探针的原料便宜易得、成本低廉、制备过程简单，适于大规模工业推广应用。 【EN】The invention discloses a benzothiazole biological thiol probe with a biological thiol detection function, which is shown in a formula (I):wherein R is hydrogen, alkyl or alkoxy. The probe of the invention has good fluorescence performance and simple synthesis, obviously enhances the fluorescence of the probe after reacting with mercaptan, shows good selectivity to the mercaptan, and can be used as a biological mercaptan fluorescent probe. In addition, the raw materials for preparing the probe are cheap and easy to obtain, the cost is low, the preparation process is simple, and the method is suitable for large-scale industrial popularization and application.