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申请号:201911326511.1 公开号:CN111122398A 主分类号:G01N15/02
摘要:【中文】本发明公开了一种微纳颗粒的检测装置及方法,装置包括样品腔室和至少两个测量腔室,各所述测量腔室与所述样品腔室之间开设有至少一个通孔,各所述测量腔室仅通过通孔与样品腔室连通,所述样品腔室中设有一公共电极,各所述测量腔室中分别设有一测量电极,所述样品腔室的第一端设有第一液体驱动装置,所述公共电极接地。本发明通过设有多个测量腔室并在各所述测量腔室与所述样品腔室之间开设有通孔,从而实现对通过通孔的微纳颗粒进行直径和浓度的检测,有效解决了无法测量宽粒径分布的样本溶液中微纳颗粒的粒径分布的问题。本发明可广泛应用于微纳颗粒检测领域中。 【EN】The invention discloses a device and a method for detecting micro-nano particles, wherein the device comprises a sample chamber and at least two measuring chambers, at least one through hole is formed between each measuring chamber and the sample chamber, each measuring chamber is only communicated with the sample chamber through the through hole, a common electrode is arranged in each sample chamber, a measuring electrode is respectively arranged in each measuring chamber, a first liquid driving device is arranged at a first end of each sample chamber, and the common electrode is grounded. According to the invention, the plurality of measuring chambers are arranged, and the through hole is formed between each measuring chamber and the sample chamber, so that the diameter and the concentration of the micro-nano particles passing through the through hole can be detected, and the problem that the particle size distribution of the micro-nano particles in a sample solution with wide particle size distribution cannot be measured is effectively solved. The invention can be widely applied to the field of micro-nano particle detection.
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申请号:201910843775.8 公开号:CN110872351A 主分类号:C07K16/30
申请人:【中文】广西科技大学【EN】Guangxi University of Science and Technology 申请日:2019.09.06 公开日:2020.03.10
摘要:【中文】本发明涉及生物技术领域,特别涉及一种特异性结合GPC3蛋白的纳米抗体GN1;所述纳米抗体GN1由重链抗体的可变区组成;所述重链抗体的可变区包括抗原决定簇互补区和骨架区;所述骨架区选自由FR1、FR2、FR3和FR4及其同源序列组成的组,所述抗原决定簇互补区选自由CDR1、CDR2和CDR3及其同源序列组成的组;所述CDR1至CDR3的氨基酸序列具有如SEQ ID NO.1‑3所示的序列;所述FR1‑4的氨基酸序列具有如SEQ ID NO.4‑7所述的序列。该抗体氨基酸序列为SEQ ID NO.8,编码该氨基酸的核苷酸序列为SEQ ID NO.9。本发明的纳米抗体GN1能特异性结合高表达GPC3蛋白的肝癌细胞,抑制肝癌细胞增殖。纳米抗体GN1的氨基酸序列或纳米抗体GN1的核苷酸序列或包含其核苷酸序列的重组质粒或包含其核苷酸序列重组质粒的重组细胞均可应用于制备诊断试剂的研发和治疗肝癌的药物。 【EN】The invention relates to the technical field of biology, in particular to a nano antibody GN1 specifically combined with GPC3 protein; the nanobody GN1 consists of the variable region of a heavy chain antibody; the variable region of the heavy chain antibody comprises an epitope-complementing region and a framework region; said framework regions are selected from the group consisting of FR1, FR2, FR3 and FR4 and their homologous sequences, and said epitope-complementing regions are selected from the group consisting of CDR1, CDR2 and CDR3 and their homologous sequences; the amino acid sequences of the CDRs 1-3 have the sequences shown as SEQ ID NO. 1-3; the amino acid sequence of FR1-4 has a sequence as shown in SEQ ID NO. 4-7. The amino acid sequence of the antibody is SEQ ID NO.8, and the nucleotide sequence for coding the amino acid is SEQ ID NO. 9. The nano antibody GN1 can be specifically bound with liver cancer cells with high expression of GPC3 protein, and can inhibit the proliferation of the liver cancer cells. The amino acid sequence of the nano antibody GN1 or the nucleotide sequence of the nano antibody GN1 or the recombinant plasmid containing the nucleotide sequence or the recombinant cell containing the nucleotide sequence recombinant plasmid can be applied to the research and development of diagnostic reagents and the medicine for treating liver cancer.
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申请号:201911341579.7 公开号:CN110984977A 主分类号:E21B49/00
摘要:【中文】本发明公开一种叠置水平井开采水合物储层实验模拟装置及方法,包括注入水容器、注水泵组、气瓶、空压机、增压泵、气体高压容器、多个水平出口管路、数据采集仪、小型水浴、恒温水浴和设置在所述恒温水浴内的水合物分布模拟装置,注入水容器与注水泵组连通;小型水浴与注入水容器的上下两端分别连通;增压泵与气体高压容器连通;所述水合物分布模拟装置内设有多个水平井水平管段,外表面上设有与水平井水平管段相通的水平井口;多个水平出口管路水平叠置在所述水合物分布模拟装置的一侧并与水平井水平管段连通。本发明利用叠置水平井在重力分异方面的优势,对目前的开采方法进行组合利用,将开采与能量补充分开,实现了产气和产水的分离。 【EN】The invention discloses an experimental simulation device and method for exploiting a hydrate reservoir stratum by a superposed horizontal well, and the experimental simulation device comprises a water injection container, a water injection pump set, a gas cylinder, an air compressor, a booster pump, a gas high-pressure container, a plurality of horizontal outlet pipelines, a data acquisition instrument, a small-sized water bath, a constant-temperature water bath and a hydrate distribution simulation device arranged in the constant-temperature water bath, wherein the water injection container is communicated with the water injection pump set; the small water bath is communicated with the upper end and the lower end of the water filling container respectively; the booster pump is communicated with the gas high-pressure container; the hydrate distribution simulation device is internally provided with a plurality of horizontal well horizontal pipe sections, and the outer surface of the hydrate distribution simulation device is provided with a horizontal well mouth communicated with the horizontal well horizontal pipe sections; and the plurality of horizontal outlet pipelines are horizontally superposed on one side of the hydrate distribution simulation device and are communicated with the horizontal pipe section of the horizontal well. The invention utilizes the advantages of the stacked horizontal wells in the aspect of gravity differentiation to combine and utilize the existing exploitation method, separate exploitation from energy supplement and realize the separation of gas production and water production.
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申请号:201911291173.2 公开号:CN111015908A 主分类号:B28B7/22
摘要:【中文】本发明提供一种先张法空心板整体钢芯模拔出装置及方法,它包括可折叠的内模装置,所述的内模装置分为左右两个互相独立的结构,包括可折叠的右内模和左内模,在右内模和左内模内侧沿轴向设有多个竖向支撑,竖向支撑为可折叠的结构,各个竖向支撑之间通过拉杆连接,拉杆用于通过钢丝绳与卷扬机连接,以将内模装置的两个互相独立的结构折叠后分别拔出。通过将各榀之间的内模互相连接,实现无需穿钢丝绳的内模装置拖出施工。本发明通过采用可以折叠的内模装置,配合能够通过牵引自动折叠的竖向牵引支撑,能够便利的将内模装置分别拖出。并能够大幅提高内模装置的脱模速度。 【EN】The invention provides a device and a method for pulling out an integral steel core mould of a pre-tensioning hollow slab, which comprises a foldable inner mould device, wherein the inner mould device is divided into a left structure and a right structure which are independent from each other, the inner sides of the right inner mould and the left inner mould are provided with a plurality of vertical supports along the axial direction, the vertical supports are foldable structures, the vertical supports are connected through pull rods, and the pull rods are connected with a winch through steel wire ropes so as to respectively pull out the two independent structures of the inner mould device after being folded. The internal molds among the trusses are connected with each other, so that the internal mold device without a steel wire rope is dragged out for construction. According to the invention, by adopting the foldable internal mold device and matching with the vertical traction support capable of being automatically folded by traction, the internal mold device can be conveniently pulled out respectively. And the demolding speed of the internal mold device can be greatly improved.
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申请号:201911401993.2 公开号:CN111057077A 主分类号:C07F3/06
申请人:【中文】安庆师范大学【EN】ANQING NORMAL University 申请日:2019.12.31 公开日:2020.04.24
摘要:【中文】本发明公开一种磺酸类锌金属有机配合物,涉及有机合成技术领域,配合物为8‑氨基喹啉1,5‑萘二磺酸锌金属配合物,8‑氨基喹啉1,5‑萘二磺酸锌金属配合物的化学式为Zn(8‑aql)2(1,5‑nd)·2H2O,本发明还提供上述配合物的制备方法,包括以下步骤:将六水合硝酸锌、叠氮酸钠、1,5‑萘二磺酸钠盐和8‑氨基喹啉在二次去离子水中,于120‑180℃下反应3天,冷却至室温,过滤、洗涤,得到配合物。本发明还提供上述配合物在检测二硫化碳和硝基苯中的应用。本发明的有益效果在于:本发明制得8‑氨基喹啉1,5‑萘二磺酸锌金属配合物既可用于检测环境中低浓度的二硫化碳,也可以用于检测环境中低浓度的硝基苯。 【EN】The invention discloses a sulfonic acid zinc metal organic complex, which relates to the technical field of organic synthesis, and the complex is 8-aminoquinoline 1, 5-naphthalene disulfonic acid zinc metal complex, and the chemical formula of the 8-aminoquinoline 1, 5-naphthalene disulfonic acid zinc metal complex is Zn (8-aql)2(1,5‑nd)·2H2The invention also provides a preparation method of the complex, which comprises the following steps: reacting zinc nitrate hexahydrate, sodium azide, 1, 5-naphthalene disulfonic acid sodium salt and 8-aminoquinoline in secondary deionized water at the temperature of 120-180 ℃ for 3 days, cooling to room temperature, filtering and washing to obtain the complex. The invention also provides application of the complex in detecting carbon disulfide and nitrobenzene. The invention has the beneficial effects that: the 8-aminoquinoline zinc 1, 5-naphthalenedisulfonate metal complex prepared by the invention can be used for detecting carbon disulfide with low concentration in the environment and can also be used for detecting nitrobenzene with low concentration in the environment.
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申请号:202010059918.9 公开号:CN111271148A 主分类号:F01L1/344
申请人:【中文】东风汽车集团有限公司【EN】DONGFENG MOTOR Corp. 申请日:2020.01.19 公开日:2020.06.12
摘要:【中文】本发明公开了一种连续可变气门驱动机构的油道结构及发动机气缸盖总成,缸盖前端主油道一端用于连通缸体主油道,另一端连通进气侧上油道和排气侧上油道,所述进气侧上油道与进气侧液压间隙调节器油道连通,所述排气侧上油道与排气侧液压间隙调节器油道和第一轴颈上油道均连通,所述排气侧液压间隙调节器油道末端设有高压油泵喷嘴,所述第一轴颈上油道上连通有排气侧VVT相位驱动器油道、进气侧VVT相位驱动器油道;缸盖后端主油道一端用于连通缸体主油道,另一端与第二轴颈上油道连通,所述第二轴颈上油道上连通有VVL相位驱动器油道。本发明解决了单一缸盖主油道无法兼顾前后两端相位驱动器的用油需求的问题。 【EN】The invention discloses an oil duct structure of a continuously variable valve driving mechanism and an engine cylinder cover assembly, wherein one end of a main oil duct at the front end of a cylinder cover is used for being communicated with a main oil duct of a cylinder body, the other end of the main oil duct is communicated with an upper oil duct at an air inlet side and an upper oil duct at an air outlet side, the upper oil duct at the air inlet side is communicated with an upper oil duct of an hydraulic lash adjuster at the air inlet side, the upper oil duct at the air outlet side is communicated with the upper oil duct of the hydraulic lash adjuster at the air outlet side and an upper oil duct of a first journal, a high-pressure oil pump nozzle is arranged at the tail end of the upper oil duct of the hydraulic lash adjuster at the; one end of a main oil duct at the rear end of the cylinder cover is communicated with the main oil duct of the cylinder body, the other end of the main oil duct is communicated with an upper oil duct of the second journal, and the upper oil duct of the second journal is communicated with an oil duct of a VVL phase driver. The invention solves the problem that the single cylinder cover main oil duct can not meet the oil demand of the phase drivers at the front end and the rear end.
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申请号:202010115429.0 公开号:CN111184012A 主分类号:A01N47/24
摘要:【中文】本发明本发明公开了一种吡唑醚菌酯乳液,包括:吡唑醚菌酯油相溶液和谷朊粉水解悬液,其中,吡唑醚菌酯分子吸附于谷朊粉寡肽链周围,吡唑醚菌酯分子与谷朊粉寡肽链相互交联形成网链结构。本发明还公开了一种制备吡唑醚菌酯乳液的方法。谷朊粉在水解后会产生氨基酸和多肽,由于氨基酸、多肽中的氨基与吡唑醚菌酯中的环状结构产生静电吸附,因此,吡唑醚菌酯分子会吸附于谷朊粉寡肽链周围,并且吡唑醚菌酯分子与谷朊粉寡肽链相互交联形成网链结构,使药物均匀分散,同时结合更加紧密,能够延长延长持效周期,提高吡唑醚菌酯的有效利用率。 【EN】The invention discloses pyraclostrobin emulsion, which comprises the following components in part by weight: the pyraclostrobin oil-phase solution and the wheat gluten hydrolyzed suspension are characterized in that pyraclostrobin molecules are adsorbed around wheat gluten oligopeptide chains, and the pyraclostrobin molecules and the wheat gluten oligopeptide chains are mutually crosslinked to form a net chain structure. The invention also discloses a method for preparing the pyraclostrobin emulsion. The amino acid and the polypeptide can be produced after the wheat gluten is hydrolyzed, and because the amino in the amino acid and the polypeptide and the annular structure in the pyraclostrobin produce electrostatic adsorption, the pyraclostrobin molecule can be adsorbed around the wheat gluten oligopeptide chain, and the pyraclostrobin molecule and the wheat gluten oligopeptide chain are mutually crosslinked to form a network chain structure, so that the medicine is uniformly dispersed, and meanwhile, the combination is tighter, the lasting period can be prolonged, and the effective utilization rate of the pyraclostrobin is improved.
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申请号:201911360798.X 公开号:CN111082506A 主分类号:H02J7/35
摘要:【中文】本发明公开了一种适用于自主多功能服务飞行器的能量管理系统及方法,包括:太阳能电池阵、太阳能调节单元、蓄电池、蓄电池调节单元、母线电容阵Cbus、控制系统、负载Load和一次母线;其中,太阳能电池阵与太阳能调节单元相连接;蓄电池与蓄电池调节单元相连接;太阳能调节单元调节太阳能电池阵的输出功率;蓄电池调节单元进行蓄电池的充放电控制;母线电容阵Cbus接在一次母线输出正回线之间;控制系统采集系统状态信息,进行控制计算,输出控制信号。本发明设计了母线恒压控制、蓄电池充电控制、MPP控制三种控制模式,使空间能源系统可根据具体工况自主切换至对应工作模式。 【EN】The invention discloses an energy management system and method suitable for an autonomous multifunctional service aircraft, which comprises the following steps: the system comprises a solar cell array, a solar energy adjusting unit, a storage battery adjusting unit, a bus capacitor array Cbus, a control system, a Load and a primary bus; the solar cell array is connected with the solar energy adjusting unit; the storage battery is connected with the storage battery adjusting unit; the solar energy adjusting unit adjusts the output power of the solar cell array; the storage battery adjusting unit is used for controlling the charging and discharging of the storage battery; the bus capacitor array Cbus is connected between the primary bus output positive return wires; the control system collects system state information, performs control calculation and outputs control signals. The invention designs three control modes of bus constant voltage control, storage battery charging control and MPP control, so that the space energy system can be automatically switched to a corresponding working mode according to specific working conditions.
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申请号:201911258657.7 公开号:CN111064779A 主分类号:H04L29/08
摘要:【中文】本发明提供一种变电站SF6在线监测装置、方法及系统,包括:SF6监测传感器,用于采集变电站SF6在线监测数据;物联网模组,包括窄带物联网模组和加密芯片,所述加密芯片用于加密SF6监测传感器采集的变电站SF6在线监测数据,所述窄带物联网模组用于发送所述加密芯片加密后的变电站SF6在线监测数据;云平台,用于接收加密后的变电站SF6在线监测数据,对加密后的变电站SF6在线监测数据进行解密,对解密后的变电站SF6在线监测数据进行处理。本发明可实现对变电站SF6在线监测数据的统一处理,减少了监测数据的传输环节,有利于降低监测网络结构的复杂程度,提升了运维效率,保障了系统的安全运行。 【EN】The invention provides a transformer substation SF6The on-line monitoring device, method and system include: SF6Monitoring sensor for collecting SF of transformer station6Monitoring data on line; the Internet of things module comprises a narrow-band Internet of things module and an encryption chip, wherein the encryption chip is used for encrypting SF6Substation SF acquired by monitoring sensor6The narrow-band Internet of things module is used for sending the encrypted substation SF6Monitoring data on line; a cloud platform for receiving the encrypted SF of the substation6Monitoring data on line, and encrypting the SF of the transformer substation6Decrypting the on-line monitoring data and decrypting the decrypted SF of the transformer substation6And processing the online monitoring data. The invention can realize SF for the transformer substation6The unified processing of the on-line monitoring data reduces the transmission link of the monitoring data, and is beneficial to reducing the complexity of the monitoring network structureThe operation and maintenance efficiency is improved and the safe operation of the system is guaranteed due to the impurity degree.
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申请号:201911340813.4 公开号:CN111084403A 主分类号:A24B3/10
摘要:【中文】本发明公开了一种中上部烟叶中温保湿变黄密集挂杆烘烤方法,属于烤烟的三段式密集挂杆烘烤工艺技术领域,主要包括三段9个步骤,在中上部烟叶主变黄期采用中温保湿变黄,保持干湿球温差为零,稳定温度烘烤35‑50小时,当烟叶变黄程度达黄片青筋时缓慢升温排湿,从而提高中上部烟叶烤后的上等烟率、橘黄烟率和均价,提高烤后烟叶学化学成分协调性和感官评吸质量,提高了烤后烟叶的质量,增加了利润,实现烟农增收。 【EN】The invention discloses a medium-temperature moisture-preserving yellowing intensive hanging rod baking method for middle-upper tobacco leaves, which belongs to the technical field of three-stage intensive hanging rod baking processes of flue-cured tobacco and mainly comprises 9 three steps, wherein the medium-temperature moisture-preserving yellowing is adopted in the main yellowing period of the middle-upper tobacco leaves, the temperature difference of a dry-wet ball is kept to be zero, the tobacco leaves are baked at a stable temperature for 35-50 hours, and the tobacco leaves are slowly heated and dehumidified when the yellowing degree of the tobacco leaves reaches yellow green ribs, so that the first-class tobacco rate, the orange tobacco rate and the average price of the middle-upper tobacco leaves after being baked are improved, the chemical component coordination and the sensory evaluation quality of the tobacco leaves after being baked are improved, the quality of the tobacco leaves after being baked is improved, the profit is.
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