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申请号:201911319338.2 公开号:CN110966064A 主分类号:F01M5/00
摘要:【中文】本发明公开了一种柴油机的机油冷却器,包括盖板和外壳,所述盖板的背面与外壳的正面固定连接,本发明涉及柴油机技术领域。该柴油机的机油冷却器,通过安装架与固定架的内部固定连接有第二进液导管,并且安装架与固定架内部远离第二进液导管的一侧固定连接有第二出液导管,外壳背面的一侧固定连接有进油管,外壳背面且位于进油管的右侧固定连接有出油管,进油管与出油管的一端均贯穿外壳并延伸至外壳的内部,进油管延伸至外壳内部的一端连通有导油管,该机油冷却器整体结构设计较为简单,改变了传统冷却器的滤芯结构,大大的降低了冷却液在冷却器中的水流阻力,并且有效地提高了冷却器对机油的冷却效果,冷却效率较高。 【EN】The invention discloses an oil cooler of a diesel engine, which comprises a cover plate and a shell, wherein the back surface of the cover plate is fixedly connected with the front surface of the shell. This oil cooler of diesel engine, through the inside fixedly connected with second feed liquor pipe of mounting bracket and mount, and the mounting bracket goes out the liquid pipe with the inside one side fixedly connected with second that keeps away from the second feed liquor pipe of mount, one side fixedly connected with at the shell back advances oil pipe, the shell back just is located the right side fixedly connected with who advances oil pipe and goes out oil pipe, advance oil pipe and the inside that the shell extended to the shell with the one end that goes out oil pipe all runs through the shell, it has oil pipe to advance the one end intercommunication that oil pipe extended to the shell inside, this oil cooler overall structure designs comparatively simply, the filter core structure of traditional cooler has been changed, great reduction the water flow resistance of coolant liquid in the cooler, and improved the cooling effect of cooler to machine oil effectively, cooling efficiency is higher.
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申请号:201911191434.3 公开号:CN110918065A 主分类号:B01J20/22
申请人:【中文】浙江工业大学【EN】ZHEJIANG UNIVERSITY OF TECHNOLOGY 申请日:2019.11.28 公开日:2020.03.27
摘要:【中文】本发明公开了一种竹粉基离子交换吸附材料及其制备方法。所述的竹粉基离子交换吸附材料含有2‑羟基丙基三甲基季铵盐和2‑羟基丙基硫酸单酯基团,其制备方法包括竹粉分别经碱液、环氧氯丙烷处理,再用三甲基胺或硫酸反应得到竹粉基离子交换吸附材料,其中竹粉:氢氧化钠:环氧氯丙烷质量比为1:0.5:1‑1:6:8,反应时间0.5‑24 h;竹粉:三甲胺的质量比为1:0.3‑1:4,反应温度30‑70℃,反应时间0.5‑5 h;竹粉:硫酸的质量比为1:4‑1:10,反应温度0‑50℃,反应时间0.5‑5 h。本发明提供的一种竹粉基离子交换吸附材料及其制备方法,制备简单、成本低,易于放大,材料廉价易得,生物相容性好,在生物活性物质分离、污水净化处理、药物分离检测等化工、生物、医药、环境等领域具有广泛的应用。 【EN】The invention discloses a bamboo powder-based ion exchange adsorption material and a preparation method thereof. The bamboo powder-based ion exchange adsorption material contains 2-hydroxypropyl trimethyl quaternary ammonium salt and 2-hydroxypropyl sulfuric acid monoester group, and the preparation method comprises the steps of respectively treating bamboo powder with alkali liquor and epoxy chloropropane, and reacting with trimethylamine or sulfuric acid to obtain the bamboo powder-based ion exchange adsorption material, wherein the bamboo powder: sodium hydroxide: the mass ratio of the epoxy chloropropane is 1:0.5:1-1:6:8, and the reaction time is 0.5-24 h; bamboo powder: the mass ratio of trimethylamine is 1:0.3-1:4, the reaction temperature is 30-70 ℃, and the reaction time is 0.5-5 h; bamboo powder: the mass ratio of the sulfuric acid is 1:4-1:10, the reaction temperature is 0-50 ℃, and the reaction time is 0.5-5 h. The bamboo powder-based ion exchange adsorption material and the preparation method thereof provided by the invention have the advantages of simple preparation, low cost, easiness in amplification, low price and easiness in obtaining of materials, good biocompatibility and wide application in the fields of chemical industry, biology, medicine, environment and the like, such as bioactive substance separation, sewage purification treatment, medicine separation detection and the like.
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申请号:201911414114.X 公开号:CN111172205A 主分类号:C12P7/58
摘要:【中文】本发明公开了一种使用双极膜电渗析装置生产葡萄糖内脂的方法,所述方法为:(1)在发酵罐中加入葡萄糖溶液、葡萄糖氧化酶和过氧化氢酶进行发酵,得到含有葡萄糖酸钠的发酵液;(2)将发酵液进行预处理,所述预处理依次包括微孔过滤、陶瓷膜处理或超滤处理以及螯合树脂处理;(3)经步骤(2)预处理后的料液用装配有双极膜和阳离子交换膜的两隔室双极膜电渗析装置进行电渗析处理,分别在料液室和碱液室得到葡萄糖酸溶液和氢氧化钠溶液;(4)将步骤(3)得到的葡萄糖酸溶液用阳离子交换树脂进行处理;(5)将步骤(4)处理后的葡萄糖酸溶液进行蒸发结晶,得到葡萄糖内酯。本发明能缩短工艺路线,降低能耗和废水排放,降低生产成本。 【EN】The invention discloses a method for producing glucolactone by using a bipolar membrane electrodialysis device, which comprises the following steps: (1) adding a glucose solution, glucose oxidase and catalase into a fermentation tank for fermentation to obtain fermentation liquor containing sodium gluconate; (2) pretreating fermentation liquor, wherein the pretreatment sequentially comprises microfiltration, ceramic membrane treatment or ultrafiltration treatment and chelating resin treatment; (3) carrying out electrodialysis treatment on the feed liquid pretreated in the step (2) by using a two-compartment bipolar membrane electrodialysis device provided with a bipolar membrane and a cation exchange membrane, and obtaining a gluconic acid solution and a sodium hydroxide solution in a feed liquid chamber and an alkali liquor chamber respectively; (4) treating the gluconic acid solution obtained in the step (3) by using cation exchange resin; (5) and (4) evaporating and crystallizing the gluconic acid solution treated in the step (4) to obtain the glucolactone. The invention can shorten the process route, reduce the energy consumption and the waste water discharge and reduce the production cost.
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申请号:201911235852.8 公开号:CN110917175A 主分类号:A61K9/52
申请人:【中文】广东东阳光药业有限公司【EN】SUNSHINE LAKE PHARMA Co.,Ltd. 申请日:2019.12.05 公开日:2020.03.27
摘要:【中文】本发明涉及一种美托洛尔缓释组合物及其制备方法,属于药物制剂领域。所述组合物,含有美托洛尔或其药学上可接受的盐和控释材料,任选地含有润滑剂和/或增塑剂。所述组合物可以采用热熔挤出制备。所述组合物易于制备,制备方法,简便易行,工序少,时间短,成本低,适于工业化生产。 【EN】The invention relates to a metoprolol sustained-release composition and a preparation method thereof, belonging to the field of pharmaceutical preparations. The composition comprises metoprolol or pharmaceutically acceptable salt thereof and a controlled release material, and optionally comprises a lubricant and/or a plasticizer. The composition may be prepared by hot melt extrusion. The composition is easy to prepare, the preparation method is simple and easy to implement, the working procedures are few, the time is short, the cost is low, and the composition is suitable for industrial production.
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申请号:202010058938.4 公开号:CN111166725A 主分类号:A61K9/22
摘要:【中文】本发明涉及一种美托洛尔缓释片剂组合物及其制备方法,属于药物制剂领域。所述组合物,含有缓释微丸,稀释剂和润滑剂,任选含有包衣材料;其中,缓释微丸包含上药微丸和缓释层,上药微丸包含空白丸芯和活性成分。所述方法采用固含量高的混合液对空白丸芯进行包衣制备上药微丸,采用热熔包衣技术制备缓释微丸,工艺快速,流畅,相对时间短,既降低生产成本又能够保证产品质量。 【EN】The invention relates to a metoprolol sustained-release tablet composition and a preparation method thereof, belonging to the field of pharmaceutical preparations. The composition comprises sustained-release pellets, a diluent and a lubricant, and optionally comprises a coating material; the sustained-release pellet comprises a drug-loading pellet and a sustained-release layer, wherein the drug-loading pellet comprises a blank pellet core and an active ingredient. The method adopts the mixed solution with high solid content to coat the blank pellet core to prepare the drug-loading pellet, adopts the hot-melt coating technology to prepare the slow-release pellet, has quick and smooth process and short relative time, reduces the production cost and ensures the product quality.
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申请号:202010113329.4 公开号:CN111141229A 主分类号:G01B11/16
摘要:【中文】本发明提供一种分布式传感光缆长距离隧道快速布设装置,包括定点式应变感测光缆和配套固定夹具,定点式应变感测光缆包括光缆内芯,光缆内芯外侧包裹有光缆护套,光缆护套外侧套设有若干定点点位套,定点点位套外侧环向设有若干凸起状的加筋环;配套固定夹具以金属材料作基底,且为薄片带状,配套固定夹具中部对应定点点位套设有弯曲槽,弯曲槽内壁对应加筋环向外延伸设有环槽,配套固定夹具两侧四周分别设有固定孔位;针对分布式光纤传感技术逐渐广泛的应用需求,以及在长距离隧道布设中还存在的施工效率低、安装要求高的问题,进行系列优化设计,使分布式光纤技术在长距离隧道工程中应用更为简易、高效。 【EN】The invention provides a distributed sensing optical cable long-distance tunnel rapid laying device which comprises a fixed point type strain sensing optical cable and a matched fixing clamp, wherein the fixed point type strain sensing optical cable comprises an optical cable inner core, an optical cable sheath wraps the outer side of the optical cable inner core, a plurality of fixed point position sleeves are sleeved on the outer side of the optical cable sheath, and a plurality of convex reinforcing rib rings are annularly arranged on the outer side of each fixed point position sleeve; the matched fixing clamp takes a metal material as a substrate and is in a thin-sheet strip shape, a bending groove is sleeved at the position of a corresponding fixed point in the middle of the matched fixing clamp, an annular groove is formed in the inner wall of the bending groove and extends outwards corresponding to the reinforcement ring, and fixing hole positions are respectively arranged on the periphery of two sides of the matched fixing clamp; aiming at the gradually wide application requirements of the distributed optical fiber sensing technology and the problems of low construction efficiency and high installation requirement in the long-distance tunnel layout, a series of optimization designs are carried out, so that the distributed optical fiber sensing technology is more simple and efficient to apply in the long-distance tunnel engineering.
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申请号:201910720543.3 公开号:CN111057142A 主分类号:C07K14/635
摘要:【中文】本发明提供了一种特立帕肽的纯化方法,包括以下步骤:1)以纯化水溶解特立帕肽粗品,控制粗品浓度并用0.45μm滤膜过滤。2)以聚合物填料为固定相的色谱柱进行梯度洗脱,以TFA水溶液为流动相A,以乙腈水溶液为流动相B。3)以十八烷基硅烷键合硅胶填料为固定相的色谱柱进行梯度洗脱,以硫酸盐缓冲溶液为流动相A,以乙腈水溶液为流动相B。4),以十八烷基硅烷键合硅胶为固定的色谱柱,先以醋酸铵和乙腈,按一定的比例进行离子交换;再以醋酸水溶液为流动相A,乙腈为流动相B,进行梯度洗脱。5)将转盐后合格馏分,浓缩后上冻干。本发明采用液相自动化设备,利用不同色谱填料结合不同流动相,制备得到单杂小于0.1%,总杂小于0.2%的精肽,且纯化总收率高达70%以上,建立了一种纯度高、纯化收率高、且自动化程度高的特立帕肽纯化工艺。 【EN】The invention provides a method for purifying teriparatide, which comprises the following steps: 1) the crude teriparatide was dissolved in purified water, the concentration of the crude was controlled and filtered through a 0.45 μm filter. 2) And (3) carrying out gradient elution by using a chromatographic column with polymer filler as a stationary phase, and taking TFA aqueous solution as a mobile phase A and acetonitrile aqueous solution as a mobile phase B. 3) And (3) performing gradient elution by using a chromatographic column with octadecylsilane chemically bonded silica filler as a stationary phase, and using a sulfate buffer solution as a mobile phase A and an acetonitrile aqueous solution as a mobile phase B. 4) Using octadecylsilane chemically bonded silica as a fixed chromatographic column, and firstly carrying out ion exchange on ammonium acetate and acetonitrile according to a certain proportion; then, the acetic acid water solution is used as a mobile phase A, and the acetonitrile is used as a mobile phase B, and gradient elution is carried out. 5) Concentrating the qualified fraction after salt conversion, and freeze-drying. According to the invention, liquid phase automation equipment is adopted, different chromatographic fillers are combined with different mobile phases, refined peptide with less than 0.1% of single impurity and less than 0.2% of total impurity is prepared, the total purification yield is up to more than 70%, and the teriparatide purification process with high purity, high purification yield and high automation degree is established.
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申请号:202010238935.9 公开号:CN111236606A 主分类号:E04G3/18
摘要:【中文】本发明公开一种悬挑脚手架的隔离系统,包括脚手架和建筑结构梁,所述脚手架的节点处和建筑结构梁之间设有第一钢板和第二钢板,所述第一钢板和第二钢板之间通过铰链转动连接,所述第一钢板的顶部开设有条形孔,所述条形孔的内部活动连接有U型螺丝,所述U型螺丝套接于脚手架上,且U型螺丝的两端均螺纹连接有螺母。本发明的第一钢板、第二钢板通过铰链活动连接,可以自由调节第一钢板、第二钢板之间的角度,第一钢板上的条形孔从而使得第一钢板可以拉动,调节第一钢板的伸出长度,以便于适用脚手架的节点处和建筑结构梁之间存在高度差的时候使用。 【EN】The invention discloses an isolation system of a cantilever scaffold, which comprises the scaffold and a building structure beam, wherein a first steel plate and a second steel plate are arranged between a node of the scaffold and the building structure beam, the first steel plate and the second steel plate are rotatably connected through a hinge, a strip-shaped hole is formed in the top of the first steel plate, a U-shaped screw is movably connected inside the strip-shaped hole, the U-shaped screw is sleeved on the scaffold, and nuts are respectively connected to two ends of the U-shaped screw in a threaded manner. The first steel plate and the second steel plate are movably connected through the hinge, the angle between the first steel plate and the second steel plate can be freely adjusted, and the first steel plate can be pulled through the strip-shaped hole in the first steel plate, so that the extension length of the first steel plate can be adjusted, and the scaffold is convenient to use when the height difference exists between the node of the scaffold and the building structure beam.
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申请号:201911341808.5 公开号:CN111061252A 主分类号:G05B23/02
申请人:【中文】浙江大学【EN】ZHEJIANG University 申请日:2019.12.24 公开日:2020.04.24
摘要:【中文】本发明涉及一种基于数据驱动的精馏塔智能看板,包括信息采集模块、信息存储模块、智能计算模块和显示模块;信息采集模块通过传感器采集数据,并将数据传输至信息存储模块;信息存储模块对数据进行即时存储和分布式管理;信息存储模块与智能计算模块相连,智能计算模块对数据进行智能分析,将关键建模变量输入基于数据驱动的模型,实现KPI软测量和过程监测,并进行故障诊断,包括软测量分析子模块、过程监控子模块、故障诊断子模块,子模块与显示模块相连。本发明利用精馏塔传感器采集的信息,基于数据驱动技术进行关键生产指标软测量,能对生产过程监控,并针对不同的场景展示不同类型的数据,具有智能化,低成本,适用性广的特点。 【EN】The invention relates to a data-driven intelligent billboard for a rectifying tower, which comprises an information acquisition module, an information storage module, an intelligent calculation module and a display module, wherein the information acquisition module is used for acquiring information; the information acquisition module acquires data through the sensor and transmits the data to the information storage module; the information storage module carries out instant storage and distributed management on the data; the intelligent modeling system comprises an information storage module, an intelligent computing module, a KPI soft measurement and process monitoring module and a fault diagnosis module, wherein the information storage module is connected with the intelligent computing module, the intelligent computing module intelligently analyzes data, inputs key modeling variables into a model based on data driving, realizes KPI soft measurement and process monitoring, and performs fault diagnosis. The invention utilizes the information collected by the rectifying tower sensor, carries out soft measurement on key production indexes based on a data driving technology, can monitor the production process, displays different types of data aiming at different scenes, and has the characteristics of intellectualization, low cost and wide applicability.
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申请号:202010047287.9 公开号:CN111244283A 主分类号:H01L51/42
申请人:【中文】广西大学【EN】GUANGXI University 申请日:2020.01.16 公开日:2020.06.05
摘要:【中文】本发明属于探测器制备技术领域,公开了一种增益型钙钛矿光电探测器、制备方法及应用,所述增益型钙钛矿光电探测器由依次层叠设置的衬底、阳极、空穴阻挡层、钙钛矿层、电子传输层和阴极组成;衬底和阳极均由透明材料制成,钙钛矿层的材料的化学式为CH3NH3PbI3。在阳极表面气相蒸镀空穴阻挡层材料;在空穴阻挡层材料上继续蒸镀碘化铅,将蒸镀有空穴阻挡层和碘化铅的基底从蒸镀设备中取出;将基底置于手套箱中,在基底上放置一铜网,铜网距离基底0.1mm,将碘甲胺粉末均匀平铺于铜网上;将基底和盖子整体放在热台上,加热退火处理;将钙钛矿和基底转移至真空蒸镀设备中,蒸镀电子传输层和阴极。本发明具有超高的外量子效率。 【EN】The invention belongs to the technical field of detector preparation, and discloses a gain type perovskite photoelectric detector, a preparation method and application, wherein the gain type perovskite photoelectric detector consists of a substrate, an anode, a hole blocking layer, a perovskite layer, an electron transport layer and a cathode which are sequentially stacked; the substrate and the anode are both made of transparent materials, and the chemical formula of the material of the perovskite layer is CH3NH3PbI3. Vapor-depositing a hole barrier material on the surface of the anode; continuously evaporating lead iodide on the material of the hole barrier layer, and taking the substrate evaporated with the hole barrier layer and the lead iodide out of the evaporation equipment; placing the substrate in a glove box, and placing a copper mesh on the substrate at a distanceUniformly spreading iodomethylamine powder on a copper net with the substrate of 0.1 mm; integrally placing the substrate and the cover on a hot table, and carrying out heating annealing treatment; the perovskite and the substrate are transferred to a vacuum evaporation device, and the electron transport layer and the cathode are evaporated. The invention has ultrahigh external quantum efficiency.
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