摘要：【中文】本发明属于医药技术领域，具体公开了一种多肽制备纯化方法。本发明在乌拉立肽制备纯化过程中使用了抑制甲硫氨酸氧化的方法，使得纯化后的乌拉立肽精制品纯度高达99.90％，甲硫氨酸氧化杂质肽控制在0.1％内。 【EN】The invention belongs to the technical field of medicines, and particularly discloses a method for preparing and purifying polypeptide. The method for inhibiting methionine oxidation is used in the process of preparing and purifying the ularitide, so that the purity of the purified ularitide refined product is up to 99.90 percent, and the methionine oxidation impurity peptide is controlled within 0.1 percent.

摘要：【中文】本发明属于汽车配件加工技术领域，特别涉及一种气门挺柱钻孔夹具，其包括基座和竖直钻孔夹具所述基座是四块钢板焊接形成的，位于所述基座最上面一块钢板为工作面板，所述基座的截面为回字形，所述工作面板上设有与气门挺柱相配合的定位槽和水平加工孔，所述定位槽的底面为弧形，所述竖直夹具包括调节杆、压板和螺母，所述压板通过螺母固定于调节杆上，所述定位槽的底部开设有定位孔，所述定位孔内插接有定位销，具有对气门挺柱定位操作简单、定位效果好、钻孔精度高等优点。 【EN】The invention belongs to the technical field of automobile accessory machining, and particularly relates to a valve tappet drilling fixture which comprises a base and a vertical drilling fixture, wherein the base is formed by welding four steel plates, the uppermost steel plate positioned on the base is a working panel, the cross section of the base is in a shape of Chinese character 'hui', a positioning groove and a horizontal machining hole which are matched with a valve tappet are arranged on the working panel, the bottom surface of the positioning groove is arc-shaped, the vertical fixture comprises an adjusting rod, a pressing plate and a nut, the pressing plate is fixed on the adjusting rod through the nut, a positioning hole is formed in the bottom of the positioning groove, and a positioning pin is inserted into the positioning hole.

摘要：【中文】本发明属于汽车配件加工技术领域，特别涉及一种气门挺柱钻孔工装，其包括基座和水平钻孔夹具，所述水平钻孔夹具包括加工板和弧形套，所述弧形套的一端与基座固定连接，所述弧形套的另一端与加工板固定连接，所述弧形套和加工板形成一部分容纳气门挺柱的腔体，所述弧形套的内壁与气门挺柱的带钻孔端外表面相配合，所述加工板上设有与气门挺柱相配合竖直加工孔，所述加工板靠近基座的一侧固定设置有与竖直加工孔相配合的钻套，具有对气门挺柱定位操作简单、定位效果好、钻孔精度高等优点。 【EN】The invention belongs to the technical field of automobile part machining, and particularly relates to a valve tappet drilling tool which comprises a base and a horizontal drilling fixture, wherein the horizontal drilling fixture comprises a machining plate and an arc-shaped sleeve, one end of the arc-shaped sleeve is fixedly connected with the base, the other end of the arc-shaped sleeve is fixedly connected with the machining plate, the arc-shaped sleeve and the machining plate form a part of cavity for accommodating a valve tappet, the inner wall of the arc-shaped sleeve is matched with the outer surface of the end, with a drilling hole, of the valve tappet, a vertical machining hole matched with the valve tappet is formed in the machining plate, and a drill sleeve matched with the vertical machining hole is fixedly arranged on one side, close to the base, of the machining plate.

摘要：【中文】本发明属于生物医药领域，具体公开了一类艾塞纳肽类似物。本发明对艾塞纳肽Exendin‑4的氨基酸序列C端的几个氨基酸结构设计，包括氨基酸的添加或缺失、氨基酸序列突变和增加可用于定点修饰的位点得到一类艾塞纳肽类似物。该类似物刺激小鼠胰岛瘤细胞分泌胰岛素的活性明显高于艾塞纳肽Ex‑4，且糖尿病模型小鼠C57BL/KsJ‑db/db体内降糖活性也显著优于艾塞纳肽Ex‑4，可用于预防、治疗或减轻糖尿病和肥胖症和/或其相关并发症等其他疾病。 【EN】The invention belongs to the field of biological medicines, and particularly discloses an exenatide peptide analogue. The invention designs a plurality of amino acid structures at the C end of the amino acid sequence of the Exendin-4 of the exenatide, including the addition or deletion of amino acids, the mutation of the amino acid sequence and the addition of sites which can be used for fixed point modification, so as to obtain an exenatide analogue. The activity of the analogue for stimulating the islet tumor cells of the mouse to secrete insulin is obviously higher than that of exenatide Ex-4, the in-vivo hypoglycemic activity of the diabetes model mouse C57BL/KsJ-db/db is also obviously better than that of exenatide Ex-4, and the analogue can be used for preventing, treating or relieving other diseases such as diabetes, obesity and/or related complications thereof.

摘要：【中文】本发明公开了一种将有机质转化成二氧化碳的转化装置，涉及碳元素转化技术领域，包括载气导管、第一样品罐、第二样品罐、加热装置、进气管、混合管、燃烧室、出水装置、注射泵、三通阀、除水装置和吸收装置，第一样品罐、第二样品罐和混合管分别通过导管与三通阀相连通，注射泵固定于第一样品罐与三通阀之间的导管上，加热装置固定于第二样品罐的外侧，载气导管的一端插入第二样品罐内，混合管第一连接口与三通阀相连通，混合管第二连接口与进气管的一端相连通，混合管第三连接口与燃烧室的入口相连通，燃烧室的内腔具有点火装置，燃烧室的出口与除水装置入口相连通，除水装置出口与吸收装置相连通。本发明能够有效提高转化实验过程中的安全性。 【EN】The invention discloses a conversion device for converting organic matters into carbon dioxide, which relates to the technical field of carbon element conversion and comprises a carrier gas guide pipe, a first sample tank, a second sample tank, a heating device, an air inlet pipe, a mixing pipe, a combustion chamber, a water outlet device, an injection pump, a three-way valve, a water removal device and an absorption device, wherein the first sample tank, the second sample tank and the mixing pipe are respectively communicated with the three-way valve through guide pipes, the injection pump is fixed on the guide pipe between the first sample tank and the three-way valve, the heating device is fixed on the outer side of the second sample tank, one end of the carrier gas guide pipe is inserted into the second sample tank, a first connecting port of the mixing pipe is communicated with the three-way valve, a second connecting port of the mixing pipe is communicated with one end of the air inlet pipe, a third connecting port of the mixing pipe is communicated with an inlet of the combustion, the outlet of the dewatering device is communicated with the absorption device. The invention can effectively improve the safety in the process of the transformation experiment.

摘要：【中文】本申请涉及一种双波段气象雷达外部标定验证方法、装置和计算机设备。所述方法包括：获取经过外部标定的双波段气象雷达对气象目标的扫描数据；根据扫描数据确定第一反射率因子矩阵和第二反射率因子矩阵；计算第一反射率因子矩阵和第二反射率因子矩阵的差，得到反射率因子差矩阵；确定反射率因子差矩阵中不为空且绝对值小于第一预设阈值的元素个数与元素总个数的比值，得到第一比值；确定反射率因子差矩阵中不为空且绝对值小于第二预设阈值的元素个数与元素总个数的比值，得到第二比值；根据第一比值和第二比值，确定双波段气象雷达的外部标定结果的准确性。本申请提供的双波段气象雷达外部标定验证方法能够实现反射率因子外部标定的准确性验证。 【EN】The application relates to a method and a device for verifying external calibration of a dual-band meteorological radar and computer equipment. The method comprises the following steps: acquiring scanning data of a weather target by an externally calibrated dual-waveband weather radar; determining a first reflectivity factor matrix and a second reflectivity factor matrix according to the scanning data; calculating the difference between the first reflectivity factor matrix and the second reflectivity factor matrix to obtain a reflectivity factor difference matrix; determining the ratio of the number of elements which are not empty and have absolute values smaller than a first preset threshold value in the reflectivity factor difference matrix to the total number of the elements to obtain a first ratio; determining the ratio of the number of elements which are not empty in the reflectivity factor difference matrix and have absolute values smaller than a second preset threshold value to the total number of the elements to obtain a second ratio; and determining the accuracy of the external calibration result of the dual-band meteorological radar according to the first ratio and the second ratio. The method for verifying the external calibration of the dual-band meteorological radar can verify the accuracy of the external calibration of the reflectivity factor.

摘要：【中文】本发明公开一种紧凑通用轻量化发动机结构，包括气缸体(1)、气缸盖(2)、飞轮壳(3)、齿轮室盖板(4)和齿轮室(5)，其特征在于：气缸体(1)与齿轮室(5)分体设置，气缸体(1)上端面与气缸盖(2)下端面连接，气缸盖(2)一端伸出气缸体(1)的端部，其下端面与飞轮壳(3)的上端面连接；其中，与气缸体(1)该端部相对的飞轮壳(3)表面径向伸出气缸体(1)侧面，在伸出气缸体(1)侧面的该表面上形成有空腔，齿轮室盖板(4)与空腔连接形成齿轮室(5)。本发明能有效利用空间，降低发动机轴向长度，从而降低自重，提高整机的适配性。 【EN】The invention discloses a compact, universal and lightweight engine structure, which comprises a cylinder body (1), a cylinder cover (2), a flywheel shell (3), a gear chamber cover plate (4) and a gear chamber (5), and is characterized in that: the cylinder body (1) and the gear chamber (5) are arranged in a split mode, the upper end face of the cylinder body (1) is connected with the lower end face of the cylinder cover (2), one end of the cylinder cover (2) extends out of the end portion of the cylinder body (1), and the lower end face of the cylinder cover is connected with the upper end face of the flywheel shell (3); the surface of the flywheel shell (3) opposite to the end part of the cylinder block (1) radially extends out of the side surface of the cylinder block (1), a cavity is formed on the surface extending out of the side surface of the cylinder block (1), and a gear chamber cover plate (4) is connected with the cavity to form a gear chamber (5). The invention can effectively utilize space and reduce the axial length of the engine, thereby reducing the self weight and improving the adaptability of the whole machine.

摘要：【中文】本发明公开了基于扫频阻抗曲线辨识的变压器绕组变形智能检测方法，结合短路阻抗法和频率响应分析法，建立变压器绕组等值电路模型，进行变压器绕组扫频阻抗曲线获取，包括如下步骤：在采样电阻R与其电压U已知的情况下，通过公式I＝U/R，即可得到流过绕组的电流I，可获得将短路阻抗法及频率响应分析法有效结合的扫频阻抗法接线方式；测试时利用导线将变压器绕组一侧短路，另一侧绕组的首端注入频率为10Hz～1MHz的正弦扫频信号测试系统中的采样电阻R_C1和R_C2的阻抗值一般为50Ω，因此流过非短路侧的电流。本发明根据元件参数值的变化情况进行变压器绕组变形的智能检测，避免了过于依赖于经验丰富的专业人员，统一了分析结论，给检修决策带来了很大的方便。 【EN】The invention discloses a transformer winding deformation intelligent detection method based on sweep frequency impedance curve identification, which combines a short-circuit impedance method and a frequency response analysis method to establish a transformer winding equivalent circuit model and acquire a transformer winding sweep frequency impedance curve, and comprises the following steps: under the condition that the sampling resistor R and the voltage U thereof are known, the current I flowing through the winding can be obtained through a formula I which is U/R, and a frequency sweep impedance method wiring mode which effectively combines a short circuit impedance method and a frequency response analysis method can be obtained; during testing, one side of the transformer winding is short-circuited by a lead, and a sine frequency sweeping signal with the frequency of 10 Hz-1MHz is injected into the head end of the winding on the other sideSampling in a test systemResistance R_C1And R_C2Is generally 50 Ω, and therefore a current on the non-short-circuited side flows. According to the invention, the intelligent detection of the transformer winding deformation is carried out according to the change condition of the element parameter value, the condition that the transformer winding deformation excessively depends on experienced professionals is avoided, the analysis conclusion is unified, and great convenience is brought to maintenance decision.