当前查询到35条专利与查询词 "Li Xiangling"相关,搜索用时0.328137秒!排序方式:
发明专利:22实用新型: 10外观设计: 3
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申请号:201910506261.3 公开号:CN110970404A 主分类号:H01L23/64
申请人:【中文】爱思开海力士有限公司【EN】SK hynix Inc. 申请日:2019.06.12 公开日:2020.04.07
摘要:【中文】本发明公开了半导体器件以及用于制造其的方法。所述半导体器件包括:电介质层;形成在电介质层之上的导电层;以及形成在电介质层与导电层之间的还原牺牲层,其中,所述还原牺牲层包括第一还原牺牲材料和第二还原牺牲材料,所述第一还原牺牲材料具有比电介质层高的电负性,并且所述第二还原牺牲材料具有比第一还原牺牲材料高的电负性。 【EN】The invention discloses a semiconductor device and a method for manufacturing the same. The semiconductor device includes: a dielectric layer; a conductive layer formed over the dielectric layer; and a reducing sacrificial layer formed between the dielectric layer and the conductive layer, wherein the reducing sacrificial layer includes a first reducing sacrificial material and a second reducing sacrificial material, the first reducing sacrificial material has higher electronegativity than the dielectric layer, and the second reducing sacrificial material has higher electronegativity than the first reducing sacrificial material.
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申请号:201911101408.7 公开号:CN110859833A 主分类号:A61K31/353
摘要:【中文】本发明涉及ZP10在制备以寨卡病毒蛋白酶为靶点的抗寨卡病毒药物中的应用,本发明通过构建基于荧光的筛选模型,研究发现化合物ZP10具有抑制寨卡病毒蛋白酶活性的功能。本发明进一步对ZP10的细胞毒性,与寨卡病毒蛋白酶的亲和力进行研究发现,ZP10具有较高的抗寨卡病毒活性,其IC50为2.3μM,EC50为7.65μM,同时ZP10自身细胞毒性较低,与寨卡病毒蛋白酶有较高的亲和力以及在转录和翻译水平抑制寨卡病毒的复制进而具备显著的抗寨卡病毒效果,这使得ZP10有较好的抗寨卡病毒研发前景,可用于制备预防或治疗寨卡病毒的药物。 【EN】The invention relates to application of ZP10 in preparation of Zika virus resistant medicaments taking Zika virus protease as a target spot, and researches and discovers that a compound ZP10 has a function of inhibiting Zika virus protease activity by constructing a fluorescence-based screening model. The invention further researches the cytotoxicity of ZP10 and the affinity of ZP10 with Zika virus protease to discover that ZP10 has higher Zika virus resistance activity and IC50At 2.3. mu.M, EC50The ZP10 has low cytotoxicity, high affinity with Zika virus protease, and obvious Zika virus resisting effect by inhibiting the replication of Zika virus at the level of transcription and translation, so that the ZP10 has good Zika virus resisting development prospect and can be used for preparing medicaments for preventing or treating Zika virus.
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申请号:202010034420.7 公开号:CN111260437A 主分类号:G06Q30/06
摘要:【中文】本发明涉及互联网技术领域,尤其涉及一种基于商品方面级情感挖掘和模糊决策的产品推荐方法、装置、计算机设备和存储介质,该方法包括:获取每个待排序商品的评论数据,从中提取各个属性对应的所有特征词‑观点词对;基于各个特征词‑观点词对的正、负情感倾向,计算每个商品每个属性上的区间型毕达哥拉斯模糊数,组成情感决策矩阵;利用Heronian算子,建立综合情感决策矩阵、用户对于各属性的偏好以及属性间相关性的评分模型;利用评分模型得到每个商品的评分结果,根据评分结果对商品进行排序。该方法能够通过分析在线商品评论,快速针对用户不同偏好自动生成产品排序,实现产品推荐。 【EN】The invention relates to the technical field of Internet, in particular to a product recommendation method, a product recommendation device, computer equipment and a storage medium based on commodity aspect level emotion mining and fuzzy decision, wherein the method comprises the following steps: obtaining comment data of each commodity to be sorted, and extracting all feature word-viewpoint word pairs corresponding to each attribute from the comment data; calculating interval type Bidao Las fuzzy numbers on each attribute of each commodity based on positive and negative emotional tendencies of each characteristic word-viewpoint word pair to form an emotional decision matrix; establishing a comprehensive emotion decision matrix, the preference of the user to each attribute and a grading model of the correlation among the attributes by using a Heronian operator; and obtaining a grading result of each commodity by using the grading model, and sequencing the commodities according to the grading result. According to the method, the product ranking can be automatically generated quickly according to different preferences of the user by analyzing the online commodity comments, and the product recommendation is realized.
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申请号:202010196451.2 公开号:CN111087377A 主分类号:C07D311/92
摘要:【中文】本发明公开了一种苯并异色满醌类化合物及其制备方法和应用。本发明发现苯并异色满醌类化合物对金黄色葡萄球菌、耐药金黄色葡萄球菌、藤黄微球菌、白色念珠菌都具有很强的抑制作用,表明苯并异色满醌类化合物有广谱和显著的抗菌活性,具有良好的应用开发前景。 【EN】The invention discloses a benzo isochroman quinone compound and a preparation method and application thereof. The invention discovers that the benzisothromanone compounds have strong inhibiting effect on staphylococcus aureus, drug-resistant staphylococcus aureus, micrococcus luteus and candida albicans, and shows that the benzisothromanone compounds have broad-spectrum and obvious antibacterial activity and good application and development prospects.
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申请号:201911364339.9 公开号:CN110958031A 主分类号:H04B1/16
申请人:【中文】上海贝岭股份有限公司【EN】SHANGHAI BELLING CORP., Ltd. 申请日:2019.12.26 公开日:2020.04.03
摘要:【中文】本发明公开了一种RS485接收器电路、集成电路及收发器。接收器电路包括:电平位移电路,用于接收RS485总线A线输入和B线输入,将A线输入的电压转换为第一电压并输出,将B线输入的电压转换为第二电压并输出,第一电压和第二电压均在预设电压范围内且所述预设电压范围与A线输入和B线输入的电压范围不完全相同;以及,比较器电路,用于接收第一电压和第二电压,比较第一电压和第二电压的电压差得到电平信号并输出;以及,输出电路,用于接收电平信号,产生与所述电平信号高低电平相同的输出信号并输出。本发明将RS485总线A线输入和B线输入转换至预设电压范围内,满足其输出所连不同端口的电压需求。 【EN】The invention discloses an RS485 receiver circuit, an integrated circuit and a transceiver. The receiver circuit includes: the level shift circuit is used for receiving the input of an A line and the input of a B line of the RS485 bus, converting the voltage input by the A line into a first voltage and outputting the first voltage, converting the voltage input by the B line into a second voltage and outputting the second voltage, wherein the first voltage and the second voltage are both in a preset voltage range, and the preset voltage range is not completely the same as the voltage ranges of the input of the A line and the input of the B line; the comparator circuit is used for receiving the first voltage and the second voltage, comparing the voltage difference of the first voltage and the second voltage to obtain a level signal and outputting the level signal; and the output circuit is used for receiving the level signal, generating an output signal with the same high level as the level signal and outputting the output signal. The invention converts the input of the A line and the input of the B line of the RS485 bus into a preset voltage range, and meets the voltage requirements of different ports connected with the output of the RS485 bus.
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申请号:201911070244.6 公开号:CN110907416A 主分类号:G01N21/64
申请人:【中文】中山大学【EN】SUN YAT-SEN University 申请日:2019.11.05 公开日:2020.03.24
摘要:【中文】本发明属于循环肿瘤细胞检测技术领域,具体公开基于空心纳米针管电穿孔系统的循环肿瘤细胞检测装置,包括:细胞培养池,所述细胞培养池包括聚二甲基硅氧烷块状物和聚碳酸酯膜,所述聚二甲基硅氧烷块状物带有中心孔,所述聚碳酸酯膜对应于中心孔的底部位置,且其上设有空心纳米针管阵列,所述中心孔与聚碳酸酯膜形成的空腔用于存放细胞悬浮液;微流沟道,用于递送药物溶液,包括带有沟道的PDMS薄膜以及ITO玻璃,所述PDMS薄膜粘连ITO玻璃的导电面;所述细胞培养池与微流沟道通过未固化的PDMS作为粘连物,两者相互整合封装。该细胞检测装置能较好的完成CTC识别后器件内的原位药物调控,具有优良的生物相容性,有效的解决CTC识别中存在的血液细胞背景干扰问题。 【EN】The invention belongs to the technical field of circulating tumor cell detection, and particularly discloses a circulating tumor cell detection device based on a hollow nano needle tube electroporation system, which comprises: the cell culture pool comprises a polydimethylsiloxane block and a polycarbonate membrane, wherein the polydimethylsiloxane block is provided with a central hole, the polycarbonate membrane corresponds to the bottom position of the central hole and is provided with a hollow nano needle tube array, and a cavity formed by the central hole and the polycarbonate membrane is used for storing cell suspension; the microfluidic channel is used for delivering a drug solution and comprises a PDMS film with a channel and ITO glass, wherein the PDMS film is adhered to a conductive surface of the ITO glass; the cell culture pool and the microfluidic channel are integrated and packaged with each other by taking uncured PDMS as an adhesive. The cell detection device can well complete in-situ drug regulation and control in a device after CTC identification, has excellent biocompatibility, and effectively solves the problem of blood cell background interference in CTC identification.
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申请号:202010080382.9 公开号:CN110917196A 主分类号:A61K31/4706
摘要:【中文】本发明公开了一种氯喹抑菌消毒液及其应用。其以质量浓度0.1‑5.0%的氯喹或氯喹衍生物为主要有效成份,pH值为4.0‑7.0。进一步可辅以天然植物来源的具有杀菌作用的植物提取物,对氯喹抑菌抗病毒作用发挥明显的协同增效作用。该药液对多种细菌、病毒均有一定的清洗、杀灭作用,尤其是对冠状病毒、HPV、HIV等病毒和细菌的传播和感染,对口腔、家居环境、暴露皮肤等细菌病毒易感部位的预防有很好的效果。而且本发明将氯喹开发为外用消毒制剂,并可进一步开发成各类卫消产品,老药新用,与同类消毒产品相比,可口服,危害性小,此类产品的上市将能更有效的保护人群做好针对病菌和病毒的防护,应用前景广阔。 【EN】The invention discloses a chloroquine antibacterial disinfectant and application thereof. Which takes chloroquine or chloroquine derivatives with mass concentration of 0.1-5.0% as main effective components and has pH value of 4.0-7.0. Furthermore, plant extracts with bactericidal effect from natural plant sources can be added to play an obvious synergistic effect on the antibacterial and antiviral effects of chloroquine. The liquid medicine has certain cleaning and killing effects on various bacteria and viruses, especially has good effects on the transmission and infection of viruses and bacteria such as coronavirus, HPV, HIV and the like, and the prevention of bacteria and virus susceptible parts such as oral cavity, household environment, exposed skin and the like. In addition, the chloroquine is developed into an external disinfectant, and can be further developed into various sanitary disinfectant products for new use of old medicines.
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申请号:201911199561.8 公开号:CN110977967A 主分类号:B25J9/16
摘要:【中文】针对强化学习中Q‑learning算法在复杂环境下难以进行路径规划的问题,将深度卷积神经网络的特征提取能力与强化学习的决策能力相结合,提出了一种基于深度强化学习的改进算法。该方法用值函数近似法代替Q‑learning中的动作值函数,设计了包含4层结构的深度卷积神经网络,以网络的输出代替传统的Q值表,解决了Q‑learning在状态空间较大时产生的维数灾难问题。在栅格环境下进行仿真实验,结果表明该方法相较于Q‑learning算法能够在复杂的环境下进行路径规划,并在新的测试集上取得了87%的识别率,具有较强的泛化能力。 【EN】Aiming at the problem that the Q-learning algorithm is difficult to perform path planning in a complex environment in reinforcement learning, the feature extraction capability of a deep convolutional neural network is combined with the decision-making capability of reinforcement learning, and an improved algorithm based on the deep reinforcement learning is provided. According to the method, a value function approximation method is used for replacing an action value function in Q-learning, a deep convolution neural network comprising a 4-layer structure is designed, the output of the network replaces a traditional Q value table, and the problem of dimension disaster generated when the Q-learning is large in state space is solved. The simulation experiment is carried out in the grid environment, and the result shows that compared with a Q-learning algorithm, the method can carry out path planning in a complex environment, obtains 87% of recognition rate on a new test set, and has strong generalization capability.
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申请号:201911211956.5 公开号:CN110982377A 主分类号:C09D163/00
摘要:【中文】本发明公开了一种轨道交通内饰用水性环氧涂料及制备方法,所述水性环氧涂料包括甲组份和乙组份;按重量份数计,甲组份包括经磷酸酯乳化剂乳化制成的双酚A环氧树脂30~50份、水10~15份及其他助剂和添加剂;按重量份数计,乙组份包括固化剂60~80份、水20~40份和其他助剂。本发明有效的克服了在不喷砂不打磨铝合金表面的附着力问题,达到甚至超过普通油性环氧涂料的附着力水平,并且具有极低的VOC含量及TVOC含量,性能稳定,且配制简单,可广泛应用于轨道交通内饰及相关领域。 【EN】The invention discloses a water-based epoxy coating for track traffic interior decoration and a preparation method thereof, wherein the water-based epoxy coating comprises a component A and a component B; the component A comprises 30-50 parts of bisphenol A epoxy resin prepared by emulsifying a phosphate ester emulsifier, 10-15 parts of water and other additives and additives in parts by weight; the component B comprises 60-80 parts by weight of curing agent, 20-40 parts by weight of water and other auxiliary agents. The invention effectively overcomes the problem of adhesive force of the aluminum alloy surface without sand blasting and polishing, reaches or even exceeds the adhesive force level of common oily epoxy coating, has extremely low VOC content and TVOC content, stable performance and simple preparation, and can be widely applied to rail transit interior trim and related fields.
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申请号:202010046650.5 公开号:CN111165802A 主分类号:A23L33/00
摘要:【中文】本发明公开了一种用于肾病非透析患者的医用营养粉及制备方法,涉及医学食品技术领域,包含如下重量份的组份:蛋白质类物质52.5‑420份,脂肪类物质87‑696份、碳水化合物263.5‑2108份、复合矿物质7.95‑63.6份、复合维生素4.17‑33.36份、牛磺酸0.4‑3.2份、单双甘油脂肪酸酯0.5‑4份、核苷酸0.09‑0.7份、左旋肉碱0.06‑0.48份、复合增稠剂9‑72份、香草香精1‑8份、阿斯巴甜0.28‑2.2份;所述的碳水化合物包含麦芽糊精194.5‑1556份、菊粉15‑120份、结晶果糖5‑40份。本发明为低蛋白配方,且所用蛋白均为优质蛋白,乳清蛋白有助于肠道吸收且具有抗氧化的作用,大豆分离蛋白可以减缓肾小球滤过率下降水平、减缓慢性肾病患者的疾病进程。 【EN】The invention discloses medical nutrition powder for a kidney disease non-dialysis patient and a preparation method thereof, relating to the technical field of medical food and comprising the following components in parts by weight: 52.5-420 parts of protein substances, 87-696 parts of fat substances, 263.5-2108 parts of carbohydrate, 7.95-63.6 parts of compound mineral substances, 4.17-33.36 parts of compound vitamin, 0.4-3.2 parts of taurine, 0.5-4 parts of mono-diglycerol fatty acid ester, 0.09-0.7 part of nucleotide, 0.06-0.48 part of L-carnitine, 9-72 parts of compound thickening agent, 1-8 parts of vanilla essence and 0.28-2.2 parts of aspartame; the carbohydrate comprises 194.5 to 1556 parts of maltodextrin, 15 to 120 parts of inulin and 5 to 40 parts of crystalline fructose. The invention is a low-protein formula, the used proteins are high-quality proteins, whey protein is beneficial to intestinal absorption and has an antioxidation effect, and the isolated soy protein can slow down the filtration rate reduction level of glomeruli and slow down the disease process of patients with chronic nephropathy.
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