摘要：【中文】本发明提供了一种基于数据融合和BP神经网络的跌倒检测系统，设置在鞋子中，用于预测跌倒，包括：第一子系统与第二子系统，分别设置在左脚用鞋与右脚用鞋中，均具有四个设置在鞋垫中的用于采集足底压力数据的薄膜压力传感器、用于采集足底加速度数据与足底角速度数据的加速计陀螺仪模块、用于进行数据传输的WIFI模块、用于进行数据处理的主控芯片以及用于供电的电池模块，其中，四个薄膜压力传感器分别设置于在鞋垫上第一脚趾、第一跖骨、第四跖骨以及足跟对应的位置，加速计陀螺仪模块、WIFI模块、主控芯片以及电池模块均设置在鞋帮外侧或集成设置到鞋底内。本发明还提供了一种基于数据融合和BP神经网络的跌倒检测系统的检测方法来预测跌倒。 【EN】The invention provides a fall detection system based on data fusion and a BP neural network, which is arranged in shoes and used for predicting fall, and comprises the following components: first subsystem and second subsystem, set up respectively in left foot is with shoes and right foot is with shoes, all have four and set up the film pressure sensor who is used for gathering plantar pressure data in the shoe-pad, an accelerometer gyro module for gathering plantar acceleration data and plantar angular velocity data, a WIFI module for carrying out data transmission, a battery module for carrying out data processing's main control chip and being used for supplying power, wherein, four film pressure sensors set up respectively in first toe on the shoe-pad, first metatarsal, the position that fourth metatarsal and heel correspond, accelerometer gyro module, the WIFI module, main control chip and battery module all set up in the upper of a shoe outside or integrated setting to the sole. The invention also provides a detection method of the fall detection system based on data fusion and the BP neural network to predict fall.

摘要：【中文】本发明公开了一种电子后视镜系统及交通工具，包括多个摄像机，显示屏和图像集成处理模块，其中，所述图像集成处理模块包括图像采集模块、图像处理模块和图像显示模块，图像处理模块基于图像采集模块采集到的图像数据和实际车辆信号选取待显示图像数据，将待显示图像重组并拼接形成整屏单画面图像，或按照预定比例沿横向或径向将待显示图像切割为连续排列的若干数量的分图像。本发明通过对多个摄像机获取图像的拼接或分割处理实现多个摄像机对应一个显示画面，并使驾驶员能够实时、准确、快速地观察并判断多个视角的视野，还通过控制实现显示画面随车辆行驶状态情况而变化显示，以保证图像显示不失真，从而大大提升行车的安全性。 【EN】The invention discloses an electronic rearview mirror system and a vehicle, which comprise a plurality of cameras, a display screen and an image integrated processing module, wherein the image integrated processing module comprises an image acquisition module, an image processing module and an image display module, the image processing module selects image data to be displayed based on the image data acquired by the image acquisition module and actual vehicle signals, recombines and splices the images to be displayed to form a whole-screen single-picture image, or cuts the images to be displayed into a plurality of sub-images which are continuously arranged along the transverse direction or the radial direction according to a preset proportion. The invention realizes that the plurality of cameras correspond to one display picture by splicing or dividing the images acquired by the plurality of cameras, enables a driver to accurately and quickly observe and judge the visual fields of a plurality of visual angles in real time, and realizes the display of the display picture along with the driving state of the vehicle by controlling so as to ensure that the image display is not distorted, thereby greatly improving the driving safety.

摘要：【中文】本发明公开了五种延长细胞寿命的粘红酵母sir2同源基因及其产物的应用，属于生物技术领域。本发明将具有延长细胞寿命的五种粘红酵母sir2同源基因hst3，hst4，sirtuin1，sirtuin 2，sirtuin 4基因在粘红酵母中敲除以观察其作用。实验结果表明敲除这五种基因可以缩短酵母细胞的的寿命，减少菌体脂肪积累，影响ATP的产生，降低TCA循环中关键酶活性，其产物具有延长酵母细胞的的寿命，提高ATP的产生，增加TCA循环中关键酶活性的功能，为治疗细胞衰老提供了新思路。 【EN】The invention discloses five rhodotorula glutinis sir2 homologous genes for prolonging the cell life and application of products thereof, belonging to the technical field of biology. The invention provides five rhodotorula glutinis sir2 homologous genes capable of prolonging the cell lifehst3，hst4，sirtuin1，sirtuin2，sirtuin 4The gene was knocked out in Rhodotorula glutinis to observe its effect. The experimental result shows that the knockout of the five genes can shorten the service life of yeast cells, reduce the accumulation of somatic fat and influence ATPThe production reduces the key enzyme activity in TCA cycle, the product has the functions of prolonging the service life of yeast cells, improving the generation of ATP and increasing the key enzyme activity in TCA cycle, and provides a new idea for treating cell aging.

摘要：【中文】本发明公开了一种改善线粒体功能的sirtuin4蛋白的应用及阐述其作用机制，属于生物技术领域。本发明将具有重构线粒体网络和改善哺乳动物衰老细胞表型功能的粘红酵母sirtuin4基因在哺乳动物细胞中重组表达。实验结果表明其可以激活受损线粒体自噬的相关蛋白，显著降低哺乳动物细胞的SA‑β‑gal活性水平，增强CK19、β1整合素的表达水平，降低细胞内ROS水平水平，明显提升细胞内ATP水平，改善线粒体形态，从而改善了线粒体网络和提高了细胞抵抗衰老的能力，为使用sirtuin4蛋白治疗线粒体功能障碍和预防衰老提供了新的策略。 【EN】The invention discloses application of a sirtuin4 protein for improving mitochondrial function and elucidating an action mechanism of the sirtuin4 protein, and belongs to the technical field of biology.A rhodotorula glutinis sirtuin4 gene with functions of reconstructing a mitochondrial network and improving the phenotype of a mammal aged cell is recombined and expressed in the mammal cell.an experimental result shows that the gene can activate related proteins of damaged mitochondrial autophagy, obviously reduce the SA- β -gal activity level of the mammal cell, enhance the expression level of CK19 and β 1 integrins, reduce the level of intracellular ROS, obviously improve the ATP level in the cell and improve the mitochondrial morphology, thereby improving the mitochondrial network and improving the anti-aging capability of the cell, and providing a new strategy for using the sirtuin4 protein to treat mitochondrial dysfunction and prevent aging.

摘要：【中文】本发明公开了一种粘红酵母去乙酰化酶2蛋白的制备及其应用，属于生物技术领域。本发明通过大肠杆菌重组表达制备粘红酵母sirtuin2蛋白的方法的步骤有：质粒的构建，大肠杆菌感受态细胞的制备，质粒转化，提取，鉴定，重组大肠杆菌蛋白表达验证，大肠杆菌发酵表达目的蛋白，提纯目的蛋白。本发明经实验发现，重组表达的粘红酵母sirtuin2蛋白具有增强线粒体功能和重构线粒体网络的功能，可用于治疗和预防线粒体功能障碍和衰老的功能性食品和药品的制备。 【EN】The invention discloses a preparation method and application of rhodotorula glutinis deacetylase 2 protein, and belongs to the technical field of biology. The method for preparing the Rhodotorula glutinis sirtuin2 protein by recombinant expression of Escherichia coli comprises the following steps: constructing plasmids, preparing escherichia coli competent cells, transforming the plasmids, extracting, identifying, verifying recombinant escherichia coli protein expression, fermenting and expressing target protein by the escherichia coli, and purifying the target protein. Experiments show that the recombinant expressed Rhodotorula glutinis sirtuin2 protein has the functions of enhancing mitochondrial function and reconstructing mitochondrial network, and can be used for preparing functional foods and medicines for treating and preventing mitochondrial dysfunction and aging.

摘要：【中文】本发明公开了一种粘红酵母sirtuin4蛋白的制备方法及其应用，属于生物技术领域。本发明通过大肠杆菌重组表达制备粘红酵母sirtuin4蛋白的方法的步骤有：质粒的构建，大肠杆菌感受态细胞的制备，质粒转化，提取，鉴定，重组大肠杆菌蛋白表达验证，大肠杆菌发酵表达目的蛋白，提纯目的蛋白。本发明经实验发现，重组表达的粘红酵母sirtuin4蛋白具有激活受损线粒体自噬相关蛋白，改善线粒体形态和增强线粒体功能的功能，为治疗和预防线粒体功能障碍和衰老的功能性食品和药品的制备提供了新的思路。 【EN】The invention discloses a preparation method and application of rhodotorula glutinis sirtuin4 protein, and belongs to the technical field of biology. The method for preparing the Rhodotorula glutinis sirtuin4 protein by recombinant expression of Escherichia coli comprises the following steps: constructing plasmids, preparing escherichia coli competent cells, transforming the plasmids, extracting, identifying, verifying recombinant escherichia coli protein expression, fermenting and expressing target protein by the escherichia coli, and purifying the target protein. Experiments show that the recombinant expressed Rhodotorula glutinis sirtuin4 protein has the functions of activating damaged mitochondrial autophagy related protein, improving mitochondrial morphology and enhancing mitochondrial function, and provides a new idea for preparing functional foods and medicines for treating and preventing mitochondrial dysfunction and aging.

摘要：【中文】本发明公开了一种改善线粒体功能的sirtuin2蛋白的应用及阐述其作用机制，属于生物技术领域。本发明将具有重构线粒体网络和改善哺乳动物衰老细胞表型功能的粘红酵母sirtuin2基因在哺乳动物细胞中重组表达。实验结果表明其可以提高融合蛋白Mfn1，Mfn2和分裂蛋白Drp1的表达水平，降低哺乳动物细胞的SA‑β‑gal活性水平，增强CK19、β1整合素的表达水平，降低细胞内ROS水平水平，明显提升细胞内ATP水平，改善线粒体形态，从而改善了线粒体网络和提高了细胞抵抗衰老的能力，为使用sirtuin2蛋白治疗线粒体功能障碍和预防衰老提供了新的策略。 【EN】The invention discloses application of a sirtuin2 protein for improving mitochondrial function and elucidating an action mechanism of the sirtuin2 protein, belonging to the technical field of biology.A rhodotorula glutinis sirtuin2 gene with functions of reconstructing a mitochondrial network and improving the phenotype of a mammal aged cell is recombined and expressed in the mammal cell.an experimental result shows that the expression level of fusion proteins Mfn1, Mfn2 and mitosin Drp1 can be improved, the SA- β -gal activity level of the mammal cell is reduced, the expression level of CK19 and β 1 integrins is enhanced, the intracellular ROS level is reduced, the intracellular ATP level is obviously improved, and the mitochondrial morphology is improved, so that the mitochondrial network is improved, the anti-aging capacity of the cell is improved, and a new strategy is provided for treating mitochondrial dysfunction and preventing aging by using the sirtuin2 protein.

摘要：【中文】本发明公开了一种高精度数字电阻卡，包括控制器、通讯接口以及若干个数字电位计，若干个数字电位计并联形成若干数字电位计组，数字电位计组串联，控制器分别与每个数字电位计连接，控制器与通讯接口连接，本发明采用数字电位计设计电阻卡，解决机械式电阻卡体积大，价格贵的问题；本发明对数字电位计进行串联及并联组合，解决数字电位计分辨率不高的问题；本发明对串并联组合数字电位计的电阻卡每一种可出现组合进行重新测量，并根据测量结果进行重新排序，并挑选其中满足精度要求的排序组合，解决基于数字电位计的电阻卡非线性及输出精度不高问题。 【EN】The invention discloses a high-precision digital resistance card, which comprises a controller, a communication interface and a plurality of digital potentiometers, wherein the digital potentiometers are connected in parallel to form a plurality of digital potentiometer groups which are connected in series, the controller is respectively connected with each digital potentiometer, and the controller is connected with the communication interface; the digital potentiometer is combined in series and parallel, so that the problem of low resolution of the digital potentiometer is solved; the invention remeasures each combination of the resistance cards of the series-parallel combination digital potentiometer, performs reordering according to the measurement result, and selects the ordering combination meeting the precision requirement, thereby solving the problems of nonlinearity and low output precision of the resistance card based on the digital potentiometer.

摘要：【中文】本发明设计了一种确定多隔舱油箱气体流动路径实验系统，属于防火抑爆技术领域，本发明系统包括气体抽吸子系统，烟气发生子系统，多隔舱油箱模拟子系统以及监测子系统；气体抽吸子系统和烟气发生子系统与多隔舱油箱模拟子系统连通；监测子系统监测气体抽吸子系统，多隔舱油箱模拟系统的运行，本发明的系统在应用于实际的机载设备之前，模拟不同气流分配方式下对惰化效果的影响，可以为确定多隔舱油箱气体流动路径提供设计依据；本发明弥补了中空纤维膜惰化技术研究中仍存在的问题，对多隔舱的研究中涉及到了气流分配方式对惰化效果的影响，并可提出具有普适意义的冲洗惰化最佳气流方式设计方案。 【EN】The invention designs an experimental system for determining a gas flow path of a multi-bay oil tank, which belongs to the technical field of fire prevention and explosion suppression, and comprises a gas suction subsystem, a smoke generation subsystem, a multi-bay oil tank simulation subsystem and a monitoring subsystem; the gas suction subsystem and the smoke generation subsystem are communicated with the multi-compartment oil tank simulation subsystem; the monitoring subsystem monitors the operation of the gas pumping subsystem and the multi-bay oil tank simulation system, and before the system is applied to actual airborne equipment, the system simulates the influence of different airflow distribution modes on the inerting effect, so that design basis can be provided for determining the gas flow path of the multi-bay oil tank; the invention makes up the problems still existing in the research of the inerting technology of the hollow fiber membrane, relates to the influence of the air flow distribution mode on the inerting effect in the research of a plurality of compartments, and can provide the design scheme of the optimum air flow mode for flushing inerting with universal significance.

摘要：【中文】本发明公开了一种新型气体冲洗与膜分离技术结合的机载制氮惰化系统，属于航空系统技术领域，通过对中空纤维膜装置中分离出的高压氮气部分提取，在涡轮机内部膨胀后，经过换热器对通入油箱的富氮气体进行冷却；低温富氮气体进入燃油箱后，降低氧浓度的同时冷凝燃油蒸汽，增强惰化效果。接着，从换热器流出的富氮气体通入中空纤维膜装置中冲洗膜丝，由于富氮气体和空气的冲入，膜丝外的氧分压不断降低，导致膜丝内外压差增大，加速膜丝内氧氮分离。同时，涡轮机带动风扇，加速膜丝外冲洗气流流速，产生负压环境。本系统提高了氧氮分离效率，保证了氮气的低温高浓度连续输出，具有装置简单，操作方便，能源利用率高，分离速度快等优点。 【EN】The invention discloses a novel airborne nitrogen inerting system combining gas flushing and membrane separation technology, which belongs to the technical field of aviation systems, and is characterized in that high-pressure nitrogen separated from a hollow fiber membrane device is partially extracted, and after the high-pressure nitrogen expands in a turbine, nitrogen-rich gas introduced into an oil tank is cooled through a heat exchanger; after the low-temperature nitrogen-rich gas enters the fuel tank, the fuel steam is condensed while the oxygen concentration is reduced, and the inerting effect is enhanced. And then, introducing the nitrogen-rich gas flowing out of the heat exchanger into the hollow fiber membrane device to flush the membrane filaments, and continuously reducing the oxygen partial pressure outside the membrane filaments due to the flushing of the nitrogen-rich gas and air to increase the internal and external pressure difference of the membrane filaments and accelerate the separation of oxygen and nitrogen in the membrane filaments. Meanwhile, the turbine drives the fan to accelerate the flow rate of the washing airflow outside the membrane wires, so that a negative pressure environment is generated. The system improves the oxygen-nitrogen separation efficiency, ensures the low-temperature high-concentration continuous output of nitrogen, and has the advantages of simple device, convenient operation, high energy utilization rate, high separation speed and the like.