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申请号:202010148808.X 公开号:CN111265458A 主分类号:A61K8/9794
申请人:【中文】王璞【EN】Wang Pu 申请日:2020.03.05 公开日:2020.06.12
摘要:【中文】本发明公开了一种组合活性物及其在制备舒缓皮肤过敏产品或药物中的应用。该组合活性物,包括以下质量份数的原料粉防己碱1‑5份、β‑谷甾醇5‑10份和麦冬根提取物8‑12份,通过粉防己碱、β‑谷甾醇和麦冬根提取物合理的配伍,可以显著抑制Th2细胞的活性及其相关基因或炎症因子的表达,在皮肤抗敏修护功效上有应用潜力,为制备舒缓皮肤过敏产品和药物提供了策略。此外,该组合活性物的制备方法简单,可被大规模生产和应用。 【EN】The invention discloses a combined active matter and an application thereof in preparing a skin allergy relieving product or a medicine, wherein the combined active matter comprises 1-5 parts by mass of tetrandrine, 5-10 parts by mass of β -sitosterol and 8-12 parts by mass of radix ophiopogonis extract, and the reasonable compatibility of the tetrandrine, β -sitosterol and the radix ophiopogonis extract can obviously inhibit the activity of Th2 cells and the expression of related genes or inflammatory factors, has application potential on the skin allergy resistance repairing efficacy, and provides a strategy for preparing the skin allergy relieving product and the medicine.
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申请号:202010148229.5 公开号:CN111249196A 主分类号:A61K8/9789
申请人:【中文】王璞【EN】Wang Pu 申请日:2020.03.05 公开日:2020.06.09
摘要:【中文】本发明公开了一种茉莉根发酵提取物及其在肌肤修复抗衰老化妆品中的应用,所述茉莉根发酵提取物,通过以下步骤制备的:取茉莉根粉碎成粗粉;将所述粗粉与南极假丝酵母脂肪酶和表面活性剂,加入到溶剂中进行发酵,得到发酵液;所述发酵液经超声处理、过滤、浓缩、经超临界萃取,即得所述茉莉根发酵提取物。本发明的茉莉根发酵提取物,含有多种小分子活性肽和氨基酸,具有促进细胞创伤的修复的功能,对细胞划伤有明显的修复作用;且发酵原来料来自药食同源的茉莉根,没有任何毒副作用;将其用于制备肌肤修复抗衰老化妆品,该化妆品能够有效修复皮肤,并且对人体皮肤无刺激性,没有任何毒副作用。 【EN】The invention discloses a jasmine root fermented extract and application thereof in skin repair and anti-aging cosmetics, wherein the jasmine root fermented extract is prepared by the following steps: pulverizing jasmine root into coarse powder; adding the coarse powder, candida antarctica lipase and a surfactant into a solvent for fermentation to obtain a fermentation liquid; and carrying out ultrasonic treatment, filtering, concentrating and supercritical extraction on the fermentation liquor to obtain the jasmine root fermentation extract. The jasmine root fermentation extract contains various small molecular active peptides and amino acids, has the function of promoting the repair of cell wounds, and has an obvious repair effect on cell scratches; the original fermentation material is from jasmine roots which are homologous in medicine and food, and has no toxic or side effect; the cosmetic can effectively repair skin, has no irritation to human skin, and has no toxic or side effect.
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申请号:201911343110.7 公开号:CN111000011A 主分类号:A23F3/34
摘要:【中文】本发明公开了唐古特青兰茶及其制备方法,所述唐古特青兰茶由唐古特青兰按以下步骤制成:1)采摘:在每年的6‑8月间,采摘整株唐古特青兰作为新鲜原料;2)清洗、切节、晾晒:将整株唐古特青兰洗净后切成1.5cm‑2cm短节原料,然后摊开置于日光下晾晒半小时,使其水分含量在45‑55%,收起待用;3)揉捻:晾晒后的短节原料置于70‑80℃热锅中,用双手拢住短节原料,沿锅壁盘旋热揉,使茶叶在手掌和锅壁间滚动翻转,至含水量在4.5‑5.5%且短节原料基本紧结时结束揉捻,揉捻的总时间为30‑40分钟,即得唐古特青兰茶成品。本发明制备方法简单,制得的唐古特青兰茶口感好,还兼具降血压的功效。 【EN】The invention discloses Tangut dragonhead tea and a preparation method thereof, wherein the Tangut dragonhead tea is prepared from Tangut dragonhead according to the following steps: 1) picking: picking the whole plant of Tanggute dracocephalum herb as a fresh raw material in 6-8 months of each year; 2) cleaning, cutting and airing: cleaning the whole plant of Tangut dragonhead, cutting into short sections of 1.5-2 cm, spreading out, airing in the sun for half an hour to ensure that the water content is 45-55%, and collecting for later use; 3) rolling: and (3) placing the dried short section raw material in a hot pot at 70-80 ℃, holding the short section raw material with two hands, circling and hot-kneading along the pot wall, rolling and turning the tea between the palm and the pot wall until the water content is 4.5-5.5% and the short section raw material is basically compact, and finishing kneading for 30-40 minutes to obtain the finished product of the Tanggute blue tea. The preparation method is simple, and the prepared Tanggute dracocephalum tea has good taste and also has the effect of reducing blood pressure.
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申请号:201911309788.3 公开号:CN111004839A 主分类号:C12Q1/6858
摘要:【中文】本发明涉及一种利用锁核酸修饰对目标区域基因突变进行富集和检测的方法。该富集方法包括:将含有待检测目标区域的核酸样本和第一引物、第二引物和阻滞扩增序列混合扩增,获得第一扩增产物;基于第一扩增产物利用第一引物、第三引物扩增获得第二扩增产物;阻滞扩增序列的3’末端含有阻滞基团,阻滞扩增序列和第一引物含有部分重叠序列,所述待检测目标区域位于阻滞扩增序列与核酸样本的匹配区域内,第一引物的3’末端位于所述待检测目标区域的上游,所述阻滞扩增序列上修饰有锁核酸,携带有所述锁核酸的碱基位于与所述待检测目标区域匹配的位置。由此可以实现对于低频基因突变的高精度检测。 【EN】The invention relates to a method for enriching and detecting gene mutation of a target region by using locked nucleic acid modification. The enrichment method comprises the following steps: mixing and amplifying a nucleic acid sample containing a target region to be detected, a first primer, a second primer and a retardation amplification sequence to obtain a first amplification product; amplifying the first amplification product by using the first primer and the third primer to obtain a second amplification product; the 3 'end of the block amplification sequence contains a block group, the block amplification sequence and the first primer contain partial overlapping sequences, the target region to be detected is located in a matching region of the block amplification sequence and a nucleic acid sample, the 3' end of the first primer is located at the upstream of the target region to be detected, locked nucleic acid is modified on the block amplification sequence, and a base carrying the locked nucleic acid is located at a position matched with the target region to be detected. Thereby, high-precision detection of low-frequency gene mutation can be realized.
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申请号:201911212600.3 公开号:CN111066831A 主分类号:A01N65/48
申请人:【中文】王浦【EN】Wang Pu 申请日:2019.12.02 公开日:2020.04.28
摘要:【中文】本发明公开了一种中草药源农药,属于农业生产技术领域。其中草药源农药原料包括霍香、黄柏、丁香、乌梅、山豆根、苦参、百部、黄连、白鲜皮、青蒿、虎杖、茵陈、白头翁、姜黄、牡丹皮、紫草、秦皮、冰片、松针和黄公藤,喷洒该农药有利于防治蔬果上的白粉病、霜霉病、灰霉病、锈病等真菌、细菌类病害和蔬果中的蓟马、红蜘蛛、蚜虫和斑潜蝇等虫害,保证蔬果的正常生长,逐步减少使用化学农药,减轻农残对蔬果的污染,促进蔬果的丰收高产,达到管用、价廉和低毒的效果。 【EN】The invention discloses a Chinese herbal medicine source pesticide, and belongs to the technical field of agricultural production. The pesticide is sprayed to prevent and treat powdery mildew, downy mildew, gray mold, rust disease and other fungi and bacterial diseases on vegetables and fruits and insect pests such as thrips, red spiders, aphids, liriomyza and the like in the vegetables and fruits, so that the normal growth of the vegetables and fruits is ensured, the use of chemical pesticides is gradually reduced, the pollution of pesticide residues to the vegetables and fruits is reduced, the harvest and high yield of the vegetables and fruits are promoted, and the effects of pipe use, low price and low toxicity are achieved.
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申请号:201911311237.0 公开号:CN111118119A 主分类号:C12Q1/6827
摘要:【中文】本发明涉及一种对目标区域基因突变进行富集和检测的方法。该富集方法包括:将含有待检测目标区域的核酸样本和第一引物、第二引物、阻滞扩增序列混合,进行第一PCR扩增获得第一扩增产物;基于第一扩增产物利用第一引物和第二引物进行第二PCR扩增获得第二扩增产物;阻滞扩增序列的3’末端含有阻滞基团,阻滞扩增序列和第一引物含有部分重叠序列,待检测目标区域位于阻滞扩增序列与核酸样本的匹配区域内,第一引物的3’末端位于待检测目标区域的上游,阻滞扩增序列与核酸样本之间存在至少一个碱基不匹配位点,所述至少一个碱基不匹配位点不同于待检测目标区域位点。由此可以实现对于低频基因突变的高精度检测。 【EN】The invention relates to a method for enriching and detecting gene mutation of a target region. The enrichment method comprises the following steps: mixing a nucleic acid sample containing a target region to be detected with a first primer, a second primer and a blocked amplification sequence, and performing first PCR amplification to obtain a first amplification product; performing second PCR amplification on the basis of the first amplification product by using the first primer and the second primer to obtain a second amplification product; the 3 'end of the amplification-retarding sequence contains a retarding group, the amplification-retarding sequence and the first primer contain partial overlapping sequences, the target region to be detected is located in a matching region of the amplification-retarding sequence and the nucleic acid sample, the 3' end of the first primer is located at the upstream of the target region to be detected, at least one base mismatching site exists between the amplification-retarding sequence and the nucleic acid sample, and the at least one base mismatching site is different from the target region to be detected. Thereby, high-precision detection of low-frequency gene mutation can be realized.
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申请号:201911402093.X 公开号:CN111079857A 主分类号:G06K9/62
申请人:【中文】北京工业大学【EN】Beijing University of Technology 申请日:2019.12.30 公开日:2020.04.28
摘要:【中文】本发明公开了一种基于过完备宽度学习模型的污水处理过程故障监测方法。本发明包括“离线训练”和“在线监测”两个阶段。“离线训练”包括:首先对采集的正常数据和部分故障数据设置标签并对训练数据进行归一化处理,标签“0”为正常状态,“1”为故障状态,然后用过完备独立成分分析方法提取正常数据的解混矩阵并计算训练数据的独立成分矩阵,然后利用宽度学习系统建立离线训练模型。“在线监测”包括:对新采集的数据进行归一化和标签处理,标签“0”为正常状态,“1”为故障状态,并用离线模型的参数模型进行在线监测。本发明不需要过多的网络层数,故障监测快速,监测准确率高。 【EN】The invention discloses a sewage treatment process fault monitoring method based on an over-complete width learning model. The invention comprises two stages of off-line training and on-line monitoring. "off-line training" includes: firstly, setting labels for collected normal data and part of fault data, carrying out normalization processing on training data, wherein the label '0' is in a normal state, and the label '1' is in a fault state, then extracting an unmixing matrix of the normal data by an over-complete independent component analysis method, calculating an independent component matrix of the training data, and then establishing an offline training model by using a width learning system. "on-line monitoring" includes: and carrying out normalization and label processing on the newly acquired data, wherein a label '0' is in a normal state, and a label '1' is in a fault state, and carrying out online monitoring by using a parameter model of an offline model. The invention does not need excessive network layers, and has rapid fault monitoring and high monitoring accuracy.
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申请号:201911119291.5 公开号:CN110854530A 主分类号:H01Q1/38
申请人:【中文】中国传媒大学【EN】Communication University of China 申请日:2019.11.15 公开日:2020.02.28
摘要:【中文】本发明公开一种基于F‑P腔的四极化MIMO天线,包括金属地板,底层介质基板,第一、二激励天线,第三、四激励天线,介质腔,上层介质基板,周期性金属贴片;上层介质基板与周期性金属贴片共同组成部分反射表面;部分反射表面、介质腔与金属地板、底层介质基板共同构成F‑P腔;部分反射表面构成F‑P腔的一端,金属地板和底层介质基板构成F‑P腔的另一端;第一、二激励天线,第三、四激励天线设置于介质腔内部。其中第一、二激励天线激励形成一个双极化微带贴片天线;第三、四激励天线激励形成两个正交的电偶极子天线。本发明所提出的技术方案可以充分利用天线结构,获得一种紧凑型、多极化、高增益MIMO天线设计。 【EN】The invention discloses a quadrapole MIMO antenna based on an F-P cavity, which comprises a metal floor, a bottom layer dielectric substrate, a first excitation antenna, a second excitation antenna, a third excitation antenna, a fourth excitation antenna, a dielectric cavity, an upper layer dielectric substrate and a periodic metal patch, wherein the bottom layer dielectric substrate is arranged on the metal floor; the upper dielectric substrate and the periodic metal patch jointly form a part of reflecting surface; the partial reflection surface and the medium cavity, the metal floor and the bottom layer medium substrate jointly form an F-P cavity; the partial reflection surface forms one end of the F-P cavity, and the metal floor and the bottom layer medium substrate form the other end of the F-P cavity; the first excitation antenna, the second excitation antenna, the third excitation antenna and the fourth excitation antenna are arranged in the dielectric cavity. The first excitation antenna and the second excitation antenna are excited to form a dual-polarized microstrip patch antenna; the third and the fourth excitation antennas are excited to form two orthogonal electric dipole antennas. The technical scheme provided by the invention can fully utilize the antenna structure to obtain a compact multi-polarization high-gain MIMO antenna design.
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申请号:201911180615.6 公开号:CN110884110A 主分类号:B29C63/02
摘要:【中文】本发明提供一种贴膜机,包括机架、左托膜装置、右托膜装置及压膜装置,左托膜装置及右托膜装置相对安装于机架上,左托膜装置及右托膜装置均用于转动地支撑由贴膜或衬纸绕卷成的卷料,压膜装置设置于机架的下方,压膜装置包括机座、下压膜辊、上压膜辊、压力调节机构及展平辊,下压膜辊可转动地安装于机座上,上压膜辊通过压力调节机构可升降地安装于下压膜辊的正上方,上压膜辊可转动地安装于压力调节机构的底部,展平辊可转动地架设于机座的一侧。该贴膜机能同时满足贴膜和垫衬纸需求,减少更换时间,提高生产效率,同时可随时切换覆膜/垫纸保护方式,满足客户的不同需求。 【EN】The invention provides a film sticking machine which comprises a rack, a left film supporting device, a right film supporting device and a film pressing device, wherein the left film supporting device and the right film supporting device are oppositely arranged on the rack, the left film supporting device and the right film supporting device are used for rotatably supporting a coiled material formed by winding a sticking film or a lining paper, the film pressing device is arranged below the rack, the film pressing device comprises a machine base, a lower film pressing roller, an upper film pressing roller, a pressure adjusting mechanism and a flattening roller, the lower film pressing roller is rotatably arranged on the machine base, the upper film pressing roller is arranged right above the lower film pressing roller in a lifting manner through the pressure adjusting mechanism, the upper film pressing roller is rotatably arranged at the bottom of the pressure adjusting mechanism, and the flattening roller is rotatably arranged on one side of the machine base. The film pasting machine can meet the requirements of film pasting and liner paper at the same time, reduce the replacement time, improve the production efficiency, and simultaneously can switch the film covering/liner paper protection mode at any time to meet different requirements of customers.
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申请号:201911180609.0 公开号:CN110844497A 主分类号:B65G35/00
摘要:【中文】本发明提供一种伸缩式防护装置,设置于地面开挖的导坑内,伸缩式防护装置包括多个滑板车、多根长导轨及限位结构,多根长导轨分别通过角钢呈多层平行固定设置于导坑的两侧,每一层的两根长导轨上滑动设置一个滑板车,限位结构设置于滑板车上,用于防止滑板车滑动脱出及带动滑板车往复滑动,当外力带动顶层的滑板车往复滑动时,依次带动其余滑板车滑动来实现多个滑板车的伸出展开或缩回叠加。本发明还提供一种提高安全性的台车系统及其控制方法。设置有该伸缩式防护装置的台车系统方便工作人员操作,提高了安全系数。 【EN】The invention provides a telescopic protective device which is arranged in a guide pit excavated on the ground, and comprises a plurality of scooters, a plurality of long guide rails and a limiting structure, wherein the long guide rails are fixedly arranged on two sides of the guide pit in a multi-layer parallel manner through angle steel respectively, a scooter is arranged on the two long guide rails of each layer in a sliding manner, the limiting structure is arranged on the scooters and used for preventing the scooters from sliding out and driving the scooters to slide in a reciprocating manner, and when an external force drives the scooter on the top layer to slide in a reciprocating manner, the rest of the scooters are sequentially driven to slide to realize the stretching, unfolding or. The invention also provides a trolley system for improving safety and a control method thereof. The trolley system provided with the telescopic protection device is convenient for workers to operate, and the safety factor is improved.
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