摘要：【中文】本发明涉及双功能分子化合物技术领域，公开了一种特异性降解tau蛋白的小分子化合物及其应用。该特异性降解tau蛋白的小分子化合物的化学结构为TBM‑L‑ULM或其药学上可接受的盐、对映体、立体异构体、溶剂化物、多晶型物或N‑氧化物，其中，TBM为tau蛋白结合部分，L为连接体基团，ULM为泛素连接酶结合部分，所述tau蛋白结合部分与所述泛素连接酶结合部分通过连接体基团连接。本发明所述的特异性降解tau蛋白的小分子化合物能增强细胞中tau蛋白的降解，从而降低tau蛋白的含量。 【EN】The invention relates to the technical field of bifunctional molecular compounds, and discloses a small molecular compound for specifically degrading tau protein and application thereof. The chemical structure of the small molecule compound for specifically degrading tau protein is TBM-L-ULM or pharmaceutically acceptable salt, enantiomer, stereoisomer, solvate, polymorph or N-oxide thereof, wherein TBM is a tau protein binding part, L is a connector group, ULM is a ubiquitin ligase binding part, and the tau protein binding part and the ubiquitin ligase binding part are connected through the connector group. The small molecule compound for specifically degrading tau protein can enhance the degradation of tau protein in cells, thereby reducing the content of tau protein.

摘要：【中文】本申请适用于车辆的摄像头监控技术领域，提供了摄像头异常检测方法、装置及终端设备，所述摄像头异常检测方法包括：获取所述摄像头拍摄的图像；将所述图像输入训练后的神经网络；通过所述训练后的神经网络识别出车厢的两个角的坐标，若所述车箱的两个角的坐标不在指定区域内，则通过所述训练后的神经网络输出用于指示所述摄像头的安装角度出现异常的提示，其中，所述车箱的两个角为距离所述摄像头最远的两个角。通过上述方法能够实现对车辆的车厢的及时监控。 【EN】The application is suitable for the technical field of camera monitoring of vehicles, and provides a camera abnormity detection method, a device and terminal equipment, wherein the camera abnormity detection method comprises the following steps: acquiring an image shot by the camera; inputting the image into a trained neural network; and recognizing the coordinates of two corners of the carriage through the trained neural network, and outputting a prompt for indicating that the installation angle of the camera is abnormal through the trained neural network if the coordinates of the two corners of the carriage are not in a specified area, wherein the two corners of the carriage are the two corners farthest away from the camera. By the method, the carriage of the vehicle can be monitored in time.

摘要：【中文】本发明提供了一种同轴线母板、公板、连接结构及印刷线路板，同轴线母板包括支撑结构、杠杆支架和接触圆环；接触圆环用于与配合圆环套设配合，接触圆环具有与公板接触面配合的母板接触面，且母板接触面和/或公板接触面具有倾斜部分；母板接触面和公板接触面的配合高度小于抵压结构的高度；杠杆支架活动设置于支撑结构，杠杆支架相对于支撑结构包括位于外侧的第一部分和位于内侧的第二部分；接触圆环安装于第一部分，第二部分用于与抵压结构抵压，以使母板接触面和公板接触面过盈配合。如此设计，接触圆环在抵压结构驱动下沿扣合方向继续运动时，倾斜结构使母板接触面和公板接触面实现过盈配合，从而保证了信号传输的稳定性。 【EN】The invention provides a coaxial mother board, a male board, a connecting structure and a printed circuit board, wherein the coaxial mother board comprises a supporting structure, a lever bracket and a contact ring; the contact circular ring is used for being sleeved and matched with the matching circular ring, the contact circular ring is provided with a motherboard contact surface matched with the male board contact surface, and the motherboard contact surface and/or the male board contact surface are/is provided with inclined parts; the matching height of the motherboard contact surface and the male plate contact surface is less than the height of the abutting structure; the lever bracket is movably arranged on the supporting structure and comprises a first part positioned on the outer side and a second part positioned on the inner side relative to the supporting structure; the contact ring is arranged on the first part, and the second part is used for being pressed against the pressing structure so that the contact surface of the motherboard is in interference fit with the contact surface of the male board. So design, when the contact ring continued to move along the lock direction under the structure drive that supports to press, the slope structure made motherboard contact surface and public board contact surface realize interference fit to signal transmission's stability has been guaranteed.

摘要：【中文】本发明公开了一种增压—保温预封压高压高温装置，将六面顶压机一级组装的压力从原来的6GPa提高到12GPa。此高压组装包括以下部分：（1）六面顶压机同步驱动的特殊材料及工艺的六个顶锤；（2）带有预密封边或带梯度组分的叶腊石传压介质；（3）两个高硬度材料增压塞；（4）两个高硬度材料增压柱；（5）一个封压金属筒；（6）一个封压保温筒；（7）由封压金属筒和封压保温筒组成的封压单元；（8）由增压塞和增压柱组成的升压单元；低热导率和高电阻率材料组成的加温、保温单元。此高压装置可以达到12GPa的压力，与现有装置相比压力提升了100％，温度超过1800℃以上。本发明具有高压、高温性能稳定可靠，样品腔尺寸较大，压力产生效率高等优点。 【EN】The invention discloses a pressurization-heat preservation pre-sealing high-pressure high-temperature device, which improves the pressure of primary assembly of a cubic press from the original 6GPa to 12 GPa. This high pressure assembly includes the following parts: (1) six top hammers of special materials and processes synchronously driven by a cubic press; (2) pyrophyllite pressure transmission medium with a pre-sealing edge or gradient components; (3) two high hardness material pressurizing plugs; (4) two high-hardness material pressurizing columns; (5) a seal-pressed metal cylinder; (6) a sealing and pressing heat preservation cylinder; (7) a sealing unit consisting of a sealing metal cylinder and a sealing heat-insulating cylinder; (8) the boosting unit consists of a boosting plug and a boosting column; a heating and heat-insulating unit consisting of low-thermal-conductivity and high-resistivity materials. The high-pressure device can reach the pressure of 12GPa, compared with the prior device, the pressure is improved by 100 percent, and the temperature exceeds 1800 ℃. The invention has the advantages of stable and reliable high-pressure and high-temperature performance, larger sample cavity size, high pressure generation efficiency and the like.

摘要：【中文】本发明公开了一种基于深度学习的人体关键点检测方法，属于计算机视觉技术领域。本发明采用扩张卷积残差网络作为人体关键点检测网络的基础网络，在头部网络中设置一种像素重排列卷积模块来实现上采样，经过两次上采样，使特征图分辨率达到最大，分别在两个分辨率的特征图上进行预测，并且在最大分辨率特征图上使用批量级别困难关键点挖掘，网络结构非常简单，计算量小，但是精度高。本发明用于公共安全、体感游戏娱乐、人机交互、标准动作分析等领域，其检测的准确度高，鲁棒性好，能够适应外界环境的各种变化。 【EN】The invention discloses a human body key point detection method based on deep learning, and belongs to the technical field of computer vision. The invention adopts the expansion convolution residual error network as the basic network of the human body key point detection network, a pixel rearrangement convolution module is arranged in the head network to realize the up-sampling, the resolution of the feature map reaches the maximum after the two up-sampling, the prediction is respectively carried out on the feature maps with two resolutions, and the key points which are difficult to excavate in batch grade are used on the feature map with the maximum resolution, the network structure is very simple, the calculated amount is small, but the precision is high. The invention is used in the fields of public safety, motion sensing game entertainment, man-machine interaction, standard action analysis and the like, has high detection accuracy and good robustness, and can adapt to various changes of external environment.

摘要：【中文】本发明公开了智能健康饮食管理系统，包括智能终端和云服务器；所述智能终端用于将用户输入的个人基本信息以及拍摄的图片或者输入的语音信息上传至云服务器，还用于显示云服务器反馈的信息；所述云服务器用于综合分析用户的个人基本信息和图像拍摄模块或语音输入模块提供的信息计算食物卡路里和份量，并汇总用户每日摄入总量，进而根据每日摄入总量与推荐的标准量进行比对，从而生成饮食建议，并发送给智能终端进行显示；本发明旨在通过拍摄、语音输入菜品食品的手段，快速识别食物卡路里值及食物的分量和健康程度，进而向用户推荐当前最健康的饮食方式。 【EN】The invention discloses an intelligent healthy diet management system, which comprises an intelligent terminal and a cloud server; the intelligent terminal is used for uploading personal basic information input by a user and a shot picture or input voice information to the cloud server and is also used for displaying information fed back by the cloud server; the cloud server is used for comprehensively analyzing personal basic information of the user and information provided by the image shooting module or the voice input module to calculate the calorie and the weight of food, summarizing the total daily intake amount of the user, comparing the total daily intake amount with the recommended standard amount to generate a diet suggestion, and sending the diet suggestion to the intelligent terminal for displaying; the method aims to quickly identify the calorie value of food and the weight and health degree of the food by means of shooting and voice inputting of dishes and foods, and further recommend the current healthiest diet mode to a user.

摘要：【中文】本发明涉及一种用于超宽带接收机中的抑制镜像频率和杂散频率干扰的电路结构，包括预选滤波器组，用于保证镜像频率抑制度；第一本振模块，与所述的预选滤波器组相连接，用于对两段宽带射频信号进行处理；第二本振模块，与所述的第一本振模块相连接，用于对两个点频进行相位噪声控制。采用了本发明的用于超宽带接收机中的抑制镜像频率和杂散频率干扰的电路结构，包括采用预选滤波器组加二次变频体制；合理中频选取及本振分配；采用双一中频变频模式。该电路结构对传统超外差接收机进行了改进，接收频率覆盖0.2～6GHz，对镜像频率及各项杂散频率的抑制度均大于70dB，有效解决了超外差接收机固有的杂散频点多的问题和超宽带接收机射频泄露干扰的问题。 【EN】The invention relates to a circuit structure for suppressing image frequency and stray frequency interference in an ultra-wideband receiver, which comprises a preselection filter group, a pre-selection filter group and a pre-selection filter group, wherein the preselection filter group is used for ensuring the image frequency suppression degree; the first local oscillator module is connected with the preselection filter bank and used for processing two sections of broadband radio frequency signals; and the second local oscillation module is connected with the first local oscillation module and is used for carrying out phase noise control on the two dot frequencies. The circuit structure for inhibiting the interference of the mirror frequency and the stray frequency in the ultra-wideband receiver comprises a pre-selection filter bank and a secondary frequency conversion system; selecting reasonable intermediate frequency and distributing local oscillators; and a double-medium frequency conversion mode is adopted. The circuit structure improves the traditional superheterodyne receiver, the receiving frequency covers 0.2-6 GHz, the suppression degree of the mirror frequency and each stray frequency is greater than 70dB, and the problems of many stray frequency points inherent to the superheterodyne receiver and the radio frequency leakage interference of the ultra-wideband receiver are effectively solved.

摘要：【中文】本发明创造提供了一种拼接积木组件，包括六面拼接积木构件、短轴、丁字轴，六面拼接积木构件包括具有边框和六个组合面的方形本体，本体其中一组合面上有两个实心结构凸起，每个组合面上还设有能与凸起、短轴相适配的凹槽；方形本体体内开设有孔径相等的三条通孔，每条通孔能与丁字轴相适配。本发明创造的拼接积木组件，可以增加积木构件之间的组合力度，通过改变六面拼接积木构件与短轴和丁字轴的拼接方式，来满足不同的组合需求。 【EN】The invention provides a spliced building block assembly, which comprises a six-face spliced building block component, a short shaft and a T-shaped shaft, wherein the six-face spliced building block component comprises a square body with a frame and six combined faces, two solid-structure bulges are arranged on one combined face of the body, and a groove which can be matched with the bulges and the short shaft is also arranged on each combined face; three through holes with the same aperture are formed in the square body, and each through hole can be matched with the T-shaped shaft. The spliced building block assembly can increase the combination strength among building block components, and meet different combination requirements by changing the splicing mode of the six-surface spliced building block components with the short shaft and the T-shaped shaft.

摘要：【中文】本发明涉及一种基于消息队列的车端数据的实时处理方法及系统，该方法包括：建立第一消息队列；车端数据的数据包上传成功后生产者向该第一消息队列发送车端数据信息，该车端数据信息包括车端数据存放位置；消费者从车端数据存放位置获取车端数据，将该车端数据转化为结构化数据后写入数据库中。根据车端数据数量多文件小的特点，基于消息队列对车端数据进行实时的预处理，每当有车端数据的数据包上传成功，消息队列就通知预处理程序立刻对该车端数据的数据包进行处理，当存在大量车端数据的情况下，可以降低整体的预处理的时间；车端数据的预处理程序将结构化的车端数据转换为结构化数据，在算法启动前，减少预处理的时间。 【EN】The invention relates to a real-time processing method and a real-time processing system for vehicle-end data based on a message queue, wherein the method comprises the following steps: establishing a first message queue; after the data packet of the vehicle-end data is uploaded successfully, the producer sends vehicle-end data information to the first message queue, wherein the vehicle-end data information comprises a vehicle-end data storage position; and the consumer acquires the vehicle end data from the vehicle end data storage position, converts the vehicle end data into structured data and writes the structured data into the database. According to the characteristics of large quantity and small files of vehicle-end data, the vehicle-end data is preprocessed in real time based on the message queue, and when the data packet of the vehicle-end data is uploaded successfully, the message queue informs a preprocessing program to process the data packet of the vehicle-end data immediately; the preprocessing program of the vehicle-end data converts the structured vehicle-end data into the structured data, and reduces preprocessing time before the algorithm is started.

摘要：【中文】本发明涉及烟气过滤设备技术领域，提供一种烟气湿法脱硫脱白装置及工艺，上述烟气湿法脱硫脱白装置包括开设有进烟口和出烟口的塔体、自进烟口朝出烟口方向依次设置的脱硫喷淋机构、第一除雾器和冷凝除湿机构，冷凝除湿机构包括冷却器、设有进液接头和出液接头的换热组件、连接于进液接头与冷却器之间的进液管、连接于出液接头与冷却器之间的出液管及设于进液管或出液管上的循环泵，换热管组设置于第一除雾器和出烟口之间，上述烟气湿法脱硫脱白装置通过对烟气进行二次降温，使烟气中的大部分水汽冷凝为液滴并从烟气中分离出来，有效降低烟气湿度，脱白效果好，能够明显消除烟气的白色视觉污染。 【EN】The invention relates to the technical field of flue gas filtration equipment, and provides a wet flue gas desulfurization and whitening device and a process, wherein the wet flue gas desulfurization and whitening device comprises a tower body provided with a smoke inlet and a smoke outlet, a desulfurization spraying mechanism, a first demister and a condensation and dehumidification mechanism which are sequentially arranged from the smoke inlet to the smoke outlet, the condensation and dehumidification mechanism comprises a cooler, a heat exchange assembly provided with a liquid inlet joint and a liquid outlet joint, a liquid inlet pipe connected between the liquid inlet joint and the cooler, a liquid outlet pipe connected between the liquid outlet joint and the cooler, and a circulating pump arranged on the liquid inlet pipe or the liquid outlet pipe, a heat exchange pipe group is arranged between the first demister and the smoke outlet, the wet flue gas desulfurization and whitening device condenses most of water vapor in the flue gas into liquid drops and separates the liquid drops from the flue gas by carrying out secondary temperature reduction on the flue gas, the humidity of the flue gas is effectively reduced, and the whitening effect is good, can obviously eliminate the white visual pollution of the smoke.