摘要：【中文】本发明公开了一种过氧化氢激活的光敏剂及其制备方法与应用。该光敏剂的结构式如式I所示，其制备方法包括如下步骤：(1)将亚甲基蓝、碳酸氢钠和连二亚硫酸钠加入到混合溶剂中，在40～60℃条件下进行反应，待反应结束后冷却至室温，分液，取有机溶剂层，得到溶液A；(2)在冰浴条件下，将三乙胺加入到溶液A中，再滴加PB‑Cl溶液进行反应，待反应结束后萃取，洗涤、干燥，减压浓缩，得到过氧化氢激活的光敏剂。本发明合成方法简单，获得的光敏剂选择性好，光动力治疗效果强，可作为光动力治疗试剂用于精准并且高效的癌症治疗，或作为光动力试剂用于活体病灶部位可激活的光动力治疗与成像诊断。 【EN】The invention discloses a photosensitizer activated by hydrogen peroxide and a preparation method and application thereof. The structural formula of the photosensitizer is shown as a formula I, and the preparation method comprises the following steps: (1) adding methylene blue, sodium bicarbonate and sodium hydrosulfite into a mixed solvent, reacting at 40-60 ℃, cooling to room temperature after the reaction is finished, separating liquid, and taking an organic solvent layer to obtain a solution A; (2) under the ice bath condition, triethylamine is added into the solution A, then PB-Cl solution is dripped to react, after the reaction is finished, extraction is carried out, washing, drying and reduced pressure concentration are carried out, and hydrogen peroxide is obtainedA living photosensitizer. The synthesis method is simple, and the obtained photosensitizer has good selectivity and strong photodynamic treatment effect, and can be used as a photodynamic treatment reagent for precise and efficient cancer treatment or used as a photodynamic reagent for activatable photodynamic treatment and imaging diagnosis of living body focus parts.

摘要：【中文】本发明提供一种气体传感器，气体传感器(100)具备氧离子传导性的固体电解质层(各层(1～6))、气体流通部(从气体导入口(10)至第二内部空腔(40)的部位)、特定气体检测部(主泵单元(21)、测定用泵单元(41)、辅助泵单元(50)等)、以及控制装置。控制装置在气体传感器(100)启动之前将向加热器(72)供给的电力设定为使得加热器(72)的温度与预先设定的目标温度之间的温差变为零，并基于该设定的电力而判定是否执行将该电力向加热器(72)供给的升温控制。 【EN】A gas sensor (100) is provided with an oxygen ion conductive solid electrolyte layer (each layer (1-6)), a gas flow section (a section from a gas inlet (10) to a second internal cavity (40)), a specific gas detection section (a main pump unit (21), a measurement pump unit (41), an auxiliary pump unit (50), and the like), and a control device. The control device sets the power supplied to the heater (72) before the gas sensor (100) is activated so that the temperature difference between the temperature of the heater (72) and a preset target temperature becomes zero, and determines whether or not to perform temperature increase control for supplying the power to the heater (72) based on the set power.

摘要：【中文】本发明公开一种具有多模态影像导航功能的酞菁钆类光敏剂及其制备方法和应用，属于光动力药物或光敏剂制备领域。该类光敏剂的结构式如式(I)所示。该类光敏剂结构明确，表现出高效的单线态氧产率；作为光动力治疗所使用的光敏剂具有制备工艺简单、安全环保、成像效果好等特点。以疏水性酞菁钆为例：通过MRI、光声以及光热成像等能快速识别检测恶性肿瘤并富集在该区域。本发明可实现无损伤、实时动态检测肿瘤病灶部位成像，进行多模态引导的同步诊断及多种联合方式的治疗，具有广阔的医学应用前景。此外，该光敏剂还可对组织和活体进行癌症诊断的多模态成像检测，从而达到对癌症进行治疗的同时进行诊断的目的。 【EN】The invention discloses a gadolinium phthalocyanine photosensitizer with a multi-modal image navigation function and a preparation method and application thereof, belonging to the field of preparation of photodynamic medicaments or photosensitizers. The structural formula of the photosensitizer is shown as a formula (I). The photosensitizer has a definite structure and shows high-efficiency singlet oxygen yield; the photosensitizer used for photodynamic therapy has the characteristics of simple preparation process, safety, environmental protection, good imaging effect and the like. With hydrophobic gadolinium phthalocyanine asExample (c): malignant tumors can be rapidly identified and detected through MRI, photoacoustic imaging, photothermal imaging and the like, and the malignant tumors are enriched in the area. The invention can realize non-damage real-time dynamic detection of tumor focus position imaging, multi-modal guided synchronous diagnosis and treatment in various combined modes, and has wide medical application prospect. In addition, the photosensitizer can also carry out multi-modal imaging detection on tissues and living bodies for cancer diagnosis, thereby achieving the purpose of diagnosis while treating cancer.

摘要：【中文】本发明提供一种气体传感器，气体传感器(100)具备氧离子传导性的固体电解质层(各层(1～6))、设置于元件前端部(101c)的气体流通部(从气体导入口(10)至第二内部空腔(40)的部位)、特定气体检测部(主泵单元(21)、测定用泵单元(41)、辅助泵单元(50)等)、以及控制装置。控制装置在气体传感器(100)启动之前将向加热器(72)供给的电力设定为使得元件前端部(101c)的温度与预先设定的目标温度之间的温差变为零，基于将该设定的电力向加热器(72)供给时的元件前端部(101c)的升温速度而判定是否持续进行将该电力向加热器(72)供给的升温控制。 【EN】A gas sensor (100) is provided with an oxygen ion conductive solid electrolyte layer (each layer (1-6)), a gas flow section (a section from a gas inlet (10) to a second internal cavity (40)) provided at an element tip section (101c), a specific gas detection section (a main pump unit (21), a measurement pump unit (41), an auxiliary pump unit (50), and the like), and a control device. The control device sets the power supplied to the heater (72) before the gas sensor (100) is activated so that the temperature difference between the temperature of the element tip portion (101c) and a preset target temperature becomes zero, and determines whether or not to continue temperature increase control for supplying the power to the heater (72) based on the temperature increase rate of the element tip portion (101c) when the set power is supplied to the heater (72).

摘要：【中文】本发明实施例公开了一种汽车室内灯控制方法及其控制系统。中央控制单元通过局域网模块接收门控档开关模块发送的开启指令和车门状态模块发送的第一车门信息，根据开启指令和第一车门信息，将室内灯状态确定为第一中间状态，根据室内灯开关模块发送的第一车灯变化指令将第一中间状态调整至目标状态，或者，根据车门状态模块发送的第二车门信息将第一中间状态调整至目标状态，相比于现有技术中由于采用硬线控制而导致的室内灯执行逻辑经常发生冲突而导致车内灯状态发生混乱的问题，通过根据车灯变化指令或者根据车门信息对车内灯状态进行自动控制，达到合理安排室内灯执行逻辑的目的，实现合理有序的控制室内灯状态以及扩充室内灯控制方式的效果。 【EN】The embodiment of the invention discloses a control method and a control system for an automobile indoor lamp. The central control unit receives an opening instruction sent by the door control gear switch module and first door information sent by the door state module through the local area network module, determining the state of the indoor lamp as a first intermediate state according to the opening instruction and the first door information, adjusting the first intermediate state to a target state according to a first vehicle lamp change instruction sent by the indoor lamp switch module, or, the first intermediate state is adjusted to the target state according to the second door information sent by the door state module, compared with the problem that the state of the interior lamp is disordered due to the fact that the execution logic of the interior lamp often conflicts caused by adopting hard-wire control in the prior art, through carrying out automatic control to the lamp state in the car according to car light change instruction or according to door information, reach the purpose of rationally arranging room lamp executive logic, realize the effect of reasonable orderly control room lamp state and extension room lamp control mode.

摘要：【中文】本发明公开了一种CRISPR/Cas13a结合电化学发光系统检测microRNA的方法与应用。该方法包括如下步骤：利用Cas13a/crRNA复合体识别Target RNA，触发Cas13a非特异性剪切RNA探针的活性，从而剪切pre‑trigger；然后将得到的产物通过T4PNK酶去磷酸化处理后得到mature‑trigger，随后进行EXPAR反应，得到dsDNA产物；再将EXPAR扩增产物与含有“光开关”分子和TPrA的溶液进行混合后进行pBPE‑ECL检测，根据获得的有效信号值，即可实现miRNAs检测的目的。 【EN】The invention discloses a method for detecting microRNA by combining CRISPR/Cas13a with an electrochemiluminescence system and application thereof. The method comprises the following steps: the Cas13a/crRNA complex is used for recognizing Target RNA, and the activity of a Cas13a nonspecific shearing RNA probe is triggered, so that pre-trigger is sheared; then, dephosphorylating the obtained product by T4PNK enzyme to obtain match-trigger, and then carrying out EXPAR reaction to obtain a dsDNA product; mixing the EXPAR amplification product with a solution containing an optical switch molecule and TPrA, and then carrying out pBPE-ECL detection, and according to the obtained effective signal value, realizing the purpose of detecting the miRNAs.

摘要：【中文】本发明涉及一种考虑复杂激励条件的车辆路面附着系数自适应估计方法，包括下列步骤：1)根据整车的单轮动力学模型设计估计器，并估计纵向轮胎力和纵向激励下路面峰值附着系数；2)基于整车二自由度运动学模型设计估计器，并估计轮胎回正力矩和侧向力激励下路面峰值附着系数；3)通过车辆状态参数判断车辆满足的激励条件，模糊推理出当前纵侧向轮胎力所能达到的极限，并据此设计融合观测器进行估计结果融合。与现有技术相比，本发明具有鲁棒性好、实时性高、快速准确等优点。 【EN】The invention relates to a vehicle road surface adhesion coefficient self-adaptive estimation method considering a complex excitation condition, which comprises the following steps of: 1) designing an estimator according to a single-wheel dynamic model of the whole vehicle, and estimating longitudinal tire force and a road surface peak value adhesion coefficient under longitudinal excitation; 2) designing an estimator based on a complete vehicle two-degree-of-freedom kinematic model, and estimating a road surface peak value attachment coefficient under the excitation of a tire aligning moment and a lateral force; 3) and judging the excitation condition met by the vehicle through the vehicle state parameters, carrying out fuzzy reasoning on the limit which can be reached by the current longitudinal and lateral tire force, and designing a fusion observer for fusion of estimation results according to the limit. Compared with the prior art, the method has the advantages of good robustness, high real-time performance, rapidness, accuracy and the like.

摘要：【中文】本发明公开了一种光声显微成像笔及成像方法，成像笔包括外壳、光纤准直器、长焦深透镜、聚焦透镜、光焦点轴向调节器、反光镜、微型扫描镜、前/侧向超声耦合器以及超声换能器，从光纤出射的激光经光纤准直器准直后，依次射入长焦深透镜、聚焦透镜，然后依次由反光镜、微型扫描镜反射，经过前/侧向超声耦合器到达样品。本发明优势在于将光声显微成像仪器做成了笔式结构，体积轻便，可以手持，并且既可以进行前向检测，也可以进行侧向检测，使得能够检测口腔、咽喉、宫颈、腹腔内脏等区域，大大扩展了光声显微仪器的应用范围；另外，通过微型扫描镜的高速扫描实现了快速的三维图像重建，极大地缩短了时间成本，能够应用于各种复杂的检测环境中。 【EN】The invention discloses a photoacoustic microscopic imaging pen and an imaging method, wherein the imaging pen comprises a shell, an optical fiber collimator, a long focal depth lens, a focusing lens, an optical focus axial regulator, a reflective mirror, a micro scanning mirror, a front/lateral ultrasonic coupler and an ultrasonic transducer, laser emitted from an optical fiber is collimated by the optical fiber collimator, then sequentially enters the long focal depth lens and the focusing lens, is then reflected by the reflective mirror and the micro scanning mirror in sequence, and reaches a sample through the front/lateral ultrasonic coupler. The invention has the advantages that the photoacoustic microscopic imaging instrument is made into a pen-shaped structure, has light volume, can be held by hands, can carry out forward detection and lateral detection, can detect the areas of oral cavity, throat, cervix, abdominal cavity viscera and the like, and greatly expands the application range of the photoacoustic microscopic instrument; in addition, the rapid three-dimensional image reconstruction is realized through the high-speed scanning of the micro scanning mirror, the time cost is greatly shortened, and the method can be applied to various complex detection environments.

摘要：【中文】本发明涉及一种涉密纸张回收设备，包括：纸张存储仓，纸张存储仓设置有落纸口；设置在落纸口下游工序的纸张识别结构，纸张识别机构用于识别待回收涉密纸张；设置在纸张识别结构下游工序的落纸控制组件，落纸控制组件用于将待回收涉密纸张回收至纸张存储仓；设置于纸张存储仓上的操作控制台，操作控制台用于控制纸张识别结构的工作模式，工作模式包括自动识别模式和手动识别模式，操作控制台还用于控制落纸控制组件的回收或停止；设置于纸张存储仓上的身份验证器，身份验证器用于对操作控制台的操作者的身份信息进行验证，当身份信息验证成功后，身份验证器授予操作控制台的操作权限，有效地提高了对涉密纸张的回收效率。 【EN】The invention relates to a confidential paper recycling device, which comprises: the paper storage bin is provided with a paper falling port; the paper identification mechanism is arranged in a downstream process of the paper dropping port and is used for identifying the confidential paper to be recovered; the paper falling control assembly is arranged in a downstream process of the paper identification structure and is used for recovering the classified paper to be recovered to the paper storage bin; the operation console is arranged on the paper storage bin and is used for controlling the working modes of the paper identification structure, the working modes comprise an automatic identification mode and a manual identification mode, and the operation console is also used for controlling the recovery or stop of the paper falling control assembly; the identity verifier is arranged on the paper storage bin and used for verifying identity information of an operator of the operation console, and after the identity information is verified successfully, the identity verifier grants the operation authority of the operation console, so that the recovery efficiency of the confidential paper is effectively improved.

摘要：【中文】本发明涉及一种蒸箱，包括具有烹饪腔的箱体、蒸汽发生器、净水箱、污水箱以及水路机构，水路机构包括供水管路、循环管路以及污水管路，供水管路的第一端与净水箱的出口相连接，供水管路的第二端与蒸汽发生器的进水口相连接，循环管路的两端分别连接供水管路的第一端和第二端，污水管路的第一端与供水管路的第二端相连接，污水管路的第二端与污水箱的入口相连接。本发明还涉及一种蒸箱的清洁方法，蒸箱启动后，净水箱内水通过循环管路对供水管路中的水进行冲洗，并经污水管路流入至污水箱内，冲洗完成后，净水箱通过供水管路对蒸汽发生器进行供水工作。该蒸箱及其清洁方法使得蒸箱的清洁程度更更高，更加安全卫生。 【EN】The invention relates to a steam box, which comprises a box body with a cooking cavity, a steam generator, a water purification box, a sewage box and a waterway mechanism, wherein the waterway mechanism comprises a water supply pipeline, a circulating pipeline and a sewage pipeline, the first end of the water supply pipeline is connected with an outlet of the water purification box, the second end of the water supply pipeline is connected with a water inlet of the steam generator, the two ends of the circulating pipeline are respectively connected with the first end and the second end of the water supply pipeline, the first end of the sewage pipeline is connected with the second end of the water supply pipeline, and the second end of the sewage pipeline is connected with an inlet of the sewage box. The invention also relates to a cleaning method of the steam box, after the steam box is started, the water in the water purifying box flushes the water in the water supply pipeline through the circulating pipeline and flows into the sewage box through the sewage pipeline, and after the flushing is finished, the water purifying box supplies water to the steam generator through the water supply pipeline. The steam box and the cleaning method thereof enable the steam box to be higher in cleaning degree, safer and more sanitary.