摘要：【中文】本发明涉及LMTK1及其Ser34磷酸化蛋白作为靶点在阿尔茨海默症状态下状态下发挥神经突触保护作用的应用。本申请通过试验验证下调阿尔茨海默模式细胞LMTK1的表达水平，可以抑制其Ser34磷酸化蛋白的表达，抑制神经突触萎缩，减少突触损伤。该发明证实了LMTK1及其Ser34磷酸化蛋白是保护阿尔茨海默症状态下神经元突触的有效靶点，可作为药物靶标用于阿尔茨海默症的治疗。 【EN】The invention relates to an LMTK1 and an application of a Ser34 phosphorylated protein thereof as a target point to play a role in protecting nerve synapses in an Alzheimer symptom state. Experiments verify that the expression level of the LMTK1 of the Alzheimer mode cell is regulated down, the expression of Ser34 phosphorylated protein can be inhibited, the neural synapse atrophy is inhibited, and the synaptic damage is reduced. The invention proves that LMTK1 and Ser34 phosphorylated protein thereof are effective targets for protecting neuronal synapses in Alzheimer's disease symptom states, and can be used as drug targets for treating Alzheimer's disease.

摘要：【中文】本发明公开了一种生产用翻转增强搅拌装置,包括反应罐体，反应罐体的顶部设有罐盖，罐盖内设有第一空腔，第一空腔内设有第一转向齿盘，罐盖内的两侧对称设有第二空腔，第二空腔内设有第二转向齿盘，第二转向齿盘与第一转向齿盘之间设有转向杆，转向杆的两端设有转向齿，转向杆的两端分别经转向齿与第一转向齿盘和第二转向齿盘连接；第二转向齿盘的底部设有第一卡接圈，第二空腔内还设有从动搅拌轴，从动搅拌轴穿插过第二转向齿盘的中部，从动搅拌轴的底部设有滑轨，滑轨上设有第二卡接圈。本发明通过整体结构的设置，可以在石墨烯制备物料冷却过程中，增加对物料的搅拌幅度，提高石墨烯生产质量。 【EN】The invention discloses a turnover reinforced stirring device for production, which comprises a reaction tank body, wherein a tank cover is arranged at the top of the reaction tank body, a first cavity is arranged in the tank cover, a first steering fluted disc is arranged in the first cavity, second cavities are symmetrically arranged on two sides in the tank cover, a second steering fluted disc is arranged in the second cavity, a steering rod is arranged between the second steering fluted disc and the first steering fluted disc, steering teeth are arranged at two ends of the steering rod, and two ends of the steering rod are respectively connected with the first steering fluted disc and the second steering fluted disc through the steering teeth; the second turns to the bottom of fluted disc and is equipped with first joint circle, still is equipped with driven (mixing) shaft in the second cavity, and driven (mixing) shaft alternates the second and turns to the middle part of fluted disc, and the bottom of driven (mixing) shaft is equipped with the slide rail, is equipped with second joint circle on the slide rail. According to the invention, through the arrangement of the integral structure, the stirring amplitude of the material can be increased in the cooling process of the material prepared from the graphene, and the production quality of the graphene is improved.

摘要：【中文】本发明公开了一种二维Cu‑MOF纳米片的制备及其在荧光检测TNP中的应用，将氯化铜和聚乙烯吡咯烷酮完全溶解于超纯水中，逐滴添加氢氧化钠水溶液后，逐滴添加抗坏血酸水溶液，离心，得第一产物，洗涤，得氧化亚铜纳米立方体；氧化亚铜纳米立方体分散于乙醇溶液中，得混合液；2‑氨基对苯二甲酸完全溶解于N,N‑二甲基甲酰胺中，得有机相溶液；混合液加入有机相溶液中，静置，离心，得第二产物，洗涤，去除溶剂，干燥，制得二维Cu‑MOF纳米片。该纳米片应用于荧光检测TNP。该制备方法通过溶剂热法合成的纳米片具有超薄的厚度、定向生长和出色的结晶度该纳米片荧光探针稳定性好、易于保存，对TNP具有良好的选择性。 【EN】The invention discloses a preparation method of a two-dimensional Cu-MOF nanosheet and application of the nanosheet in fluorescence detection of TNP (trinitrotoluene), which comprises the steps of completely dissolving copper chloride and polyvinylpyrrolidone in ultrapure water, dropwise adding an aqueous sodium hydroxide solution, dropwise adding an aqueous ascorbic acid solution, centrifuging to obtain a first product, and washing to obtain a cuprous oxide nanocube; dispersing the cuprous oxide nanocubes in an ethanol solution to obtain a mixed solution; 2-amino terephthalic acid is completely dissolved in N, N-dimethylformamide to obtain an organic phase solution; and adding the mixed solution into an organic phase solution, standing, centrifuging to obtain a second product, washing, removing the solvent, and drying to obtain the two-dimensional Cu-MOF nanosheet. The nanosheet is applied to fluorescence detection of TNP. The nanosheet synthesized by the solvothermal method has ultrathin thickness, directional growth and excellent crystallinity, and the nanosheet fluorescent probe has good stability, is easy to store and has good selectivity on TNP.

摘要：【中文】本发明公开了医学影像诊断辅助设备，包括影像诊断辅助桌，所述影像诊断辅助桌的一侧外表面设置有抗静电置物结构，所述影像诊断辅助桌的另一侧外表面设置有可拆式置杯结构，所述影像诊断辅助桌的前端外表面设置有病例工具置放结构。本发明通过病例工具置放结构，医护人员可以将病例单与笔支集中收纳起来，可以方便医护人员下次的取用，有利于人们的使用，通过抗静电置物结构，可以方便放置患者随时携带的金属物品，还可以消除患者身上随带的静电，避免对成像造成影响，以便于医护人员做出最佳的诊断，通过可拆式置杯结构，可以方便医护人员放置水杯，可以避免水杯被碰倒而导致设备出现故障，有利于人们的使用。 【EN】The invention discloses medical image diagnosis auxiliary equipment which comprises an image diagnosis auxiliary table, wherein an antistatic object placing structure is arranged on the outer surface of one side of the image diagnosis auxiliary table, a detachable cup placing structure is arranged on the outer surface of the other side of the image diagnosis auxiliary table, and a case tool placing structure is arranged on the outer surface of the front end of the image diagnosis auxiliary table. According to the medical cup, through the case tool placing structure, medical staff can collect and store a case sheet and a pen in a centralized manner, the medical staff can take and use the case sheet and the pen conveniently for the next time, the use of people is facilitated, through the antistatic object placing structure, metal objects carried by the patient at any time can be placed conveniently, static electricity carried by the patient at any time can be eliminated, the imaging is prevented from being influenced, the medical staff can make the best diagnosis, through the detachable cup placing structure, the medical staff can place a cup conveniently, the phenomenon that the equipment breaks down due to the fact that the cup is knocked down can be avoided, and the use of people is facilitated.

摘要：【中文】本发明公开了一种基于自定义的高精度时间同步调整实现高精度时间输出的装置和方法，其包括了输入时间差处理模块、时间同步粗调模块、系统时钟数字环模块、时间同步精调模块、时钟时间调整跟踪算法模块、高精度时间输出接口模块。通过输入时间戳采样模块获取输入时间信号和本地高精度时间输出模块输出信号相位采样，取得输入输出时间差数据，然后由时钟时间调整跟踪算法处理模块输出时钟跟踪控制数据，控制系统时钟数字锁相环实现系统时钟频率跟踪，同时输出时间调整控制数据对时间同步粗调模块进行时间调整，然后对粗调模块不能实现的小粒度的剩余调整量通过时间跟踪算法处理模块控制时间同步精调模块，从而实现高精度的时间相位同步。 【EN】The invention discloses a device and a method for realizing high-precision time output based on self-defined high-precision time synchronization adjustment. The input timestamp sampling module is used for acquiring input time signals and phase sampling of output signals of the local high-precision time output module, input and output time difference data are acquired, then the clock time adjustment tracking algorithm processing module outputs clock tracking control data, a system clock digital phase-locked loop is controlled to realize system clock frequency tracking, meanwhile, the time adjustment control data are output to perform time adjustment on the time synchronization coarse adjustment module, and then the time synchronization fine adjustment module is controlled by the time tracking algorithm processing module according to residual adjustment amount of small granularity which cannot be realized by the coarse adjustment module, so that high-precision time phase synchronization is realized.

摘要：【中文】本发明公开了一种用于防御文本恶意样本的对抗生成网络及其训练方法，利用对抗生成网络框架中的生成模型(Generator)和判别模型(Discriminator)进行恶意样本的防御与生成。生成器部分由自编码器(Auto‑encoder)构成，将离散的文本数据映射到连续的高维隐藏空间中，由此生成器可以利用隐藏向量生成恶意文本。判别器即判别模型，用于识别数据。生成模型生成的恶意文本将被打上真实标签与真实样本同时输入判别模型中，来进行判别模型的训练。加入恶意样本训练的判别模型能够对文本数据准确高效的识别。生成模型利用判别模型对恶意样本的评估分数以及文本数据与恶意样本的差别进行训练，来生成攻击力更强的恶意样本。由于训练过程中恶意样本的加入和对抗性的网络训练过程，网络识别文本数据能力和抗干扰性、防御能力都大幅提升。 【EN】The invention discloses a countermeasure generation network for defending text malicious samples and a training method thereof, which utilize a generation model (Generator) and a discriminant model (Discrimator) in a framework of the countermeasure generation network to defend and generate the malicious samples. The generator part is composed of an Auto-encoder (Auto-encoder) and maps discrete text data into a continuous high-dimensional hidden space, so that the generator can generate malicious text by using hidden vectors. The discriminator is a discrimination model for identifying data. And (3) the malicious text generated by the generation model is printed with a real label and is simultaneously input into the discrimination model together with the real sample so as to train the discrimination model. The discrimination model trained by the malicious sample is added, so that the text data can be accurately and efficiently identified. The generation model utilizes the discrimination model to train the evaluation score of the malicious sample and the difference between the text data and the malicious sample so as to generate the malicious sample with stronger attack power. Due to the addition of malicious samples and the antagonistic network training process in the training process, the text data recognition capability, the anti-interference capability and the defense capability of the network are greatly improved.

摘要：【中文】本发明公开了一种以半夏叶片诱导珠芽的方法，以半夏无菌苗的叶片为外植体，接入珠芽诱导培养基中，应用植物生长调节剂ZT、TDZ和IAA不同浓度配制的培养基对外植体进行诱导，使半夏离体叶片产生珠芽。只需一步就能产生珠芽，珠芽数量多，需要时间约为40 d，用时短，成本低，而且不受时间季节制约，可在短时间内生产出大量的珠芽，省时省力，为半夏生产提供大量质优价廉的种苗，将取得巨大经济效益和社会效益。本发明方法具有操作简单、工序少、成本低、稳定性好、安全高效等优点。 【EN】The invention discloses a method for inducing bulbil by using pinellia ternate leaves, which comprises the steps of taking the leaves of pinellia ternate aseptic seedlings as explants, inoculating the leaves into a bulbil induction culture medium, and inducing the explants by using culture media prepared by different concentrations of plant growth regulators ZT, TDZ and IAA to enable the pinellia ternate leaves in vitro to generate bulbil. The method can produce the bulbels only by one step, has large quantity of bulbels, needs about 40 days, has short time, low cost and no time and season limitation, can produce a large quantity of bulbels in a short time, saves time and labor, provides a large quantity of high-quality and low-price seedlings for the production of pinellia ternata, and can obtain huge economic benefit and social benefit. The method has the advantages of simple operation, few working procedures, low cost, good stability, safety, high efficiency and the like.

摘要：【中文】本发明公开了一种基于注意力机制生成摘要的方法来生成文本摘要，本发明一共包括两个阶段：第一个阶段是句子排序过程，第二阶段是摘要生成过程，其输入是通过第一阶段得到的与文章主题最相关的N个句子。在第一阶段中，对于带有标题的文章本文提出一种监督式的排序方法，首先计算每一个句子与标题之间相似度，再根据相似度对文章进行排序，最后选取相似度最高的N个句子。对于第二阶段，本发明提出了一种新的计算编码器和解码器之间注意分布的方法，即在不同时间里，解码器应该关注编码器中的不同部分。本发明通过排序方法和摘要生成方法，缓解了文章过长时必须直接截断一部分文本作为摘要生成模型的输入所导致的文章信息衰减问题。 【EN】The invention discloses a method for generating an abstract based on an attention mechanism to generate a text abstract, which comprises two stages in total: the first stage is a sentence ordering process and the second stage is a summary generation process, and the input of the summary generation process is the N sentences which are most relevant to the article topics and obtained by the first stage. In the first stage, a supervised sorting method is provided for articles with titles, similarity between each sentence and the title is calculated, the articles are sorted according to the similarity, and finally N sentences with the highest similarity are selected. For the second stage, the present invention proposes a new way of calculating the attention distribution between the encoder and the decoder, i.e. at different times the decoder should focus on different parts of the encoder. The invention solves the problem of article information attenuation caused by directly truncating a part of text as the input of the abstract generation model when the article is too long through the sorting method and the abstract generation method.

摘要：【中文】本发明公开了一种基于E1的精密时钟同步技术，在传统的只有频率同步的E1链路上实现PTP‑E1协议，从而实现了在E1链路上对相位偏差的测量，实现主从系统的时间同步。该技术包括E1模块、PTP‑E1协议模块、用户接口模块、CPU模块、本地时钟模块、系统频率相位调整模块、本地时钟信号产生模块，所述E1模块实现E1的编解码，所述PTP‑E1协议模块实现主从授时协议，所述CPU模块实现系统配置及主从偏差计算，所述本地时钟模块为系统提供基准频率，所述系统频率相位调整模块实现对系统频率相位的调整，所述本地时钟信号产生模块产生时间信号，为系统和下游设置提供准确的时间。该技术可在满足传统E1频率同步功能的同时实现相位同步，从而实现时间的同步。 【EN】The invention discloses a precision clock synchronization technology based on E1, which realizes PTP-E1 protocol on the traditional E1 link with only frequency synchronization, thereby realizing the measurement of phase deviation on the E1 link and realizing the time synchronization of a master system and a slave system. The technology comprises an E1 module, a PTP-E1 protocol module, a user interface module, a CPU module, a local clock module, a system frequency phase adjusting module and a local clock signal generating module, wherein the E1 module realizes coding and decoding of E1, the PTP-E1 protocol module realizes a master-slave time service protocol, the CPU module realizes system configuration and master-slave deviation calculation, the local clock module provides reference frequency for a system, the system frequency phase adjusting module realizes adjustment of the system frequency phase, and the local clock signal generating module generates a time signal to provide accurate time for the system and downstream setting. The technology can realize phase synchronization and time synchronization while satisfying the traditional E1 frequency synchronization function.

摘要：【中文】本发明公开了一种以半夏愈伤组织诱导块茎的方法，以半夏无菌苗的叶片诱导出的愈伤组织为材料，接入愈伤组织增殖与分化培养基中，应用6‑BA、TDZ、S₃₃₀₇、IAA和NAA植物生长调节剂和浓度不同组合配制成的培养基，将半夏愈伤组织直接诱导出块茎。这几种植物生长调节剂配合使用，不仅有利于半夏愈伤组织增殖，还能提高半夏诱导小块茎的分化率。该方法具有操作简单、成本低、分化率高、重复性好以及安全高效等优点。 【EN】The invention discloses a method for inducing tubers by using pinellia ternata callus, which is characterized in that callus induced by leaves of pinellia ternata aseptic seedlings is used as a material, the material is inoculated into a callus proliferation and differentiation culture medium, and 6-BA, TDZ and S are applied₃₃₀₇The IAA and NAA plant growth regulators and culture media prepared by different concentrations directly induce tuber from pinellia tuber callus. The plant growth regulators are used together, so that the proliferation of pinellia ternata callus is facilitated, and the differentiation rate of pinellia ternata-induced small tubers is increased. The method has the advantages of simple operation, low cost, high differentiation rate, good repeatability, safety, high efficiency and the like.