摘要：【中文】本发明公开了一种与非综合征型先天性上颌尖牙缺失易感性诊断相关的SNP标志物及其应用，SNP标志物rs2043556位于pri‑miRNA‑605，其多态性为A/G，并在此基础上开发了该SNP在先天性上颌尖牙缺失易感性诊断试剂盒中的应用。本发明通过SNP生物标志物和诊断试剂盒的研制和应用,可使得先天性上颌尖牙缺失易感性的诊断更加方便高效，并为发现具有潜在治疗价值的新型小分子药物靶标提供帮助。 【EN】The invention discloses an SNP marker related to non-syndrome congenital maxillary canine tooth loss susceptibility diagnosis and application thereof, wherein the SNP marker rs2043556 is located at pri-miRNA-605, the polymorphism of the SNP marker is A/G, and the application of the SNP marker in an congenital maxillary canine tooth loss susceptibility diagnosis kit is developed on the basis. By the development and application of the SNP biomarker and the diagnosis kit, the congenital maxillary canine tooth loss susceptibility can be diagnosed more conveniently and efficiently, and help is provided for finding a novel small molecular drug target with potential therapeutic value.

摘要：【中文】本发明涉及一种玉米事件T抗‑4及其使用方法，所述玉米植物的核酸序列包括SEQ ID NO：1或其互补序列、或者SEQ ID NO：2或其互补序列。由本发明中玉米事件T抗‑4产生的植株对草甘膦除草剂具有较好的耐受性。 【EN】The present invention relates to a corn event T-anti-4 and methods of use thereof, the nucleic acid sequence of the corn plant comprising SEQ ID NO: 1 or a complementary sequence thereof, or SEQ ID NO: 2 or the complement thereof. Plants produced by the maize event T-resistant-4 of the present invention have better tolerance to glyphosate herbicides.

摘要：【中文】本发明公开了一种病毒检测系统及其微流控芯片。微流控芯片包括：液体储存单元，用于存储检测过程中使用或产生的液体；核酸纯化单元，连通于液体储存单元，核酸纯化单元用于纯化样品液以获取核酸物质；扩增检测单元，包括主管道、多个反应池及多个支管道，扩增检测单元通过主管道与核酸纯化单元连通，各反应池通过支管道与主管道连通，反应池用于不同样品液的核酸物质进行扩增与检测。集成了核酸提取，核酸纯化以及核酸扩增与检测的多功能微流控芯片。能够实现一次加样的前提下，自动完成核酸扩增与检测的全部步骤的需求，设置多个反应池，可以同时实现对多个样品液的扩增与检测，检测效率高。 【EN】The invention discloses a virus detection system and a micro-fluidic chip thereof. The micro-fluidic chip includes: a liquid storage unit for storing liquid used or generated in the detection process; the nucleic acid purification unit is communicated with the liquid storage unit and is used for purifying the sample liquid to obtain a nucleic acid substance; the amplification detection unit comprises a main pipeline, a plurality of reaction tanks and a plurality of branch pipelines, the amplification detection unit is communicated with the nucleic acid purification unit through the main pipeline, each reaction tank is communicated with the main pipeline through the branch pipeline, and the reaction tanks are used for amplifying and detecting nucleic acid substances of different sample liquids. The multifunctional microfluidic chip integrates nucleic acid extraction, nucleic acid purification, nucleic acid amplification and detection. Under the prerequisite that can realize the application of sample once, the demand of accomplishing all steps of nucleic acid amplification and detection voluntarily sets up a plurality of reaction tanks, can realize the amplification and the detection to a plurality of sample liquid simultaneously, and detection efficiency is high.

摘要：【中文】本发明公开了一种deplazolid(LCB01‑0371)在偶发分枝杆菌感染中的应用。本发明以CLSI推荐的抗非结核分枝杆菌药物linezolid作为对照，采用微孔板二倍稀释法进行deplazolid抗偶发分枝杆菌活性测定，结果表明，deplazolid对临床分离的偶发分枝杆菌活性明显优于linezolid，大多是linezolid抑菌活性的2‑4倍，有望发掘出deplazolid在治疗偶发分枝杆菌感染疾病中的新用途。 【EN】The invention discloses application of multiplazolid (LCB01-0371) in mycobacterium fortuitum infection. According to the invention, the nonpuberculosis mycobacterium medicament linezolid recommended by CLSI is used as a reference, and the multiplazolid anti-mycobacterium fortuitum activity determination is carried out by adopting a microplate double dilution method, and the result shows that the activity of the multiplazolid on clinically separated mycobacterium fortuitum is obviously superior to that of the linezolid, most of the multiplazolid is 2-4 times of the bacteriostatic activity of the linezolid, and the new application of the multiplazolid in treating mycobacterium fortuitum infection diseases is expected to be developed.

摘要：【中文】本发明公开了一种电化学制备叠氮化铜/叠氮化亚铜薄膜的方法。所述方法以具有微纳米结构的含铜薄膜材料作为阳极，以含N₃^‑的溶液为电解液，在通电条件下含铜薄膜在阳极完成叠氮化反应，反应结束后，干燥，得到含叠氮化铜/叠氮化亚铜的薄膜。本发明利用电化学方法，在液相环境中直接制备具有微纳米结构的叠氮化铜/叠氮化亚铜薄膜，简单高效，制备过程安全，可操作性强，适用范围广。同时，制备工艺与MEMS工艺兼容，可将叠氮化铜/叠氮化亚铜薄膜直接集成在微器件或者芯片上，促进叠氮化铜/叠氮化亚铜材料的应用。 【EN】The invention discloses a method for electrochemically preparing a copper azide/cuprous azide film. The method takes a copper-containing film material with a micro-nano structure as an anode and N₃^‑The solution is electrolyte, the copper-containing film finishes the nitridizing reaction at the anode under the condition of electrifying, and after the reaction is finished, the copper-containing film/cuprous azide-containing film is obtained by drying. The method directly prepares the copper azide/cuprous azide film with the micro-nano structure in a liquid phase environment by using an electrochemical method, and has the advantages of simplicity, high efficiency, safe preparation process, strong operability and wide application range. Meanwhile, the preparation process is compatible with the MEMS process, and the copper azide/cuprous azide film can be directly integrated on a micro device or a chip, so that the application of the copper azide/cuprous azide material is promoted.

摘要：【中文】本发明公开了一种sutezolid(PNU‑100480)在鸟分枝杆菌复合群感染中的应用。本发明以CLSI推荐的抗非结核分枝杆菌药物利奈唑胺作为对照，采用微孔板二倍稀释法进行sutezolid抗鸟分枝杆菌活性测定，结果证明，sutezolid对临床分离的鸟分枝杆菌活性明显优于利奈唑胺，大多是利奈唑胺抑菌活性的4～8倍。本发明为发掘出sutezolid在治疗鸟分枝杆菌感染疾病中的新用途提供重要依据。 【EN】The invention discloses an application of sutezolid (PNU-100480) in mycobacterium avium complex infection. According to the invention, the CLSI recommended non-tuberculous mycobacterium drug linezolid is used as a reference, and a microplate double dilution method is adopted to carry out the activity determination of the capability of the. The invention provides an important basis for discovering new application of sutezolid in treating mycobacterium avium infection diseases.

摘要：【中文】本发明涉及有机金属化合物、包括其的有机发光器件和诊断组合物。由式1表示的有机金属化合物，其中，在式1中，M、L₁、L₂、n1和n2各自与说明书的详细描述中定义的相同。式1 M(L₁)_n1(L₂)_n2 【EN】The present invention relates to organometallic compounds, organic light emitting devices including the same, and diagnostic compositions. An organometallic compound represented by formula 1, wherein, in formula 1, M, L₁、L₂N1 and n2 are each independently of the otherThe same as defined in the detailed description of the specification. Formula 1M (L)₁)_n1(L₂)_n2