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申请号:201911222505.1 公开号:CN110841076A 主分类号:A61K47/69
申请人:【中文】扬州市中医院【EN】YANGZHOU HOSPITAL OF TCM 申请日:2019.12.03 公开日:2020.02.28
摘要:【中文】本发明属于生物制药技术领域,具体涉及一种靶向修饰的龙葵碱白蛋白纳米粒及其制备方法和应用。本发明采用PEG和生物活性多肽同时对龙葵碱白蛋白纳米粒药物进行靶向修饰,同时,在龙葵碱白蛋白纳米粒的制备过程中采用还原剂来还原白蛋白分子,使得制备得到的靶向修饰的龙葵碱白蛋白纳米粒药物具有还原响应能力及可降解性,且能够有效控制龙葵碱药物输送到达靶点和药物释放,同时,体外实验及动物模型实验表明,本发明的靶向修饰的龙葵碱白蛋白纳米粒能够明显抑制前列腺癌肿瘤细胞的增殖,具有良好的临床应用前景。 【EN】The invention belongs to the technical field of biological pharmacy, and particularly relates to targeted modified solanine albumin nanoparticles as well as a preparation method and application thereof. The invention adopts PEG and bioactive polypeptide to simultaneously carry out targeted modification on the solanine albumin nanoparticle medicament, and simultaneously adopts a reducing agent to reduce albumin molecules in the preparation process of the solanine albumin nanoparticle, so that the prepared targeted modified solanine albumin nanoparticle medicament has reduction response capability and degradability, can effectively control the solanine medicament to reach a target point and release the medicament, and simultaneously, in vitro experiments and animal model experiments show that the targeted modified solanine albumin nanoparticle can obviously inhibit the proliferation of prostate cancer tumor cells and has good clinical application prospect.
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申请号:201911361965.2 公开号:CN110894959A 主分类号:F24C7/00
摘要:【中文】本发明公开了家居、装饰设备技术领域的一种壁炉仿真火焰装置,包括箱体、雾化机构和输气装置;所述箱体包括侧板、顶板、灯光组件、框架和底板,所述侧板通过螺栓固定于所述框架的外侧壁,所述箱体的右侧壁插接有水源接头,所述顶板的顶部通过螺栓固定于所述框架的顶部,所述顶板的顶部镶嵌有液晶控制板,所述顶板的内部开有方形出气通孔,所述灯光组件通过螺栓固定于所述顶板的底部;在雾气储存箱的两侧安装有两组风机和雾化箱,在每个雾化箱的内部各安装一个超声波雾化器,两个超声波雾化器同时使用能够增大管路中的水雾生成量,两组风机和雾化箱能够提高水雾的排出量,水雾与灯光配合使用,从而能够提高火焰的逼真效果。 【EN】The invention discloses a fireplace simulation flame device in the technical field of home furnishing and decoration equipment, which comprises a box body, an atomization mechanism and a gas transmission device, wherein the box body is provided with a first end and a second end; the box body comprises a side plate, a top plate, a light assembly, a frame and a bottom plate, wherein the side plate is fixed on the outer side wall of the frame through a bolt, a water source connector is inserted into the right side wall of the box body, the top of the top plate is fixed on the top of the frame through a bolt, a liquid crystal control plate is embedded in the top of the top plate, a square air outlet through hole is formed in the top plate, and the light assembly is fixed on the bottom of the top plate through a bolt; two sets of fans and atomization boxes are installed on two sides of the fog storage box, an ultrasonic atomizer is installed in each atomization box, the two ultrasonic atomizers can increase the generation amount of water fog in a pipeline when being used simultaneously, the two sets of fans and the atomization boxes can improve the discharge amount of the water fog, and the water fog is matched with light to improve the vivid effect of flame.
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申请号:201911282804.4 公开号:CN110991070A 主分类号:G06F30/20
摘要:【中文】本发明涉及一种变电站二次设备三维数字化建设方法,包括以下步骤:针对装置级二次设备,根据其外观特征进行三维建模,得到变电站二次设备三维物理模型;针对装置级二次设备,根据其位置信息以及参数信息,建立生成变电站二次设备数字化信息模型;将变电站二次设备三维物理模型和变电站二次设备数字化信息模型对应关联,生成变电站二次设备三维数字化模型。本发明充分考虑到输变电工程二次三维数字化设计的需要,发挥三维可视化程度高的优势,提高了输变电工程的建设效率。 【EN】The invention relates to a three-dimensional digital construction method for secondary equipment of a transformer substation, which comprises the following steps: performing three-dimensional modeling on the device-level secondary equipment according to appearance characteristics of the device-level secondary equipment to obtain a three-dimensional physical model of the secondary equipment of the transformer substation; aiming at the device-level secondary equipment, establishing and generating a digital information model of the secondary equipment of the transformer substation according to the position information and the parameter information of the device-level secondary equipment; and correspondingly associating the transformer substation secondary equipment three-dimensional physical model with the transformer substation secondary equipment digital information model to generate a transformer substation secondary equipment three-dimensional digital model. The method fully considers the requirement of secondary three-dimensional digital design of the power transmission and transformation project, exerts the advantage of high three-dimensional visualization degree, and improves the construction efficiency of the power transmission and transformation project.
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申请号:201911295102.X 公开号:CN110984217A 主分类号:E02D29/02
摘要:【中文】本发明提供了一种建筑施工中地下管线槽的保护方法,包括以下步骤:S1.在管线槽的顶部土方进行第一次开挖,以使所述管线槽顶部全部露出;S2.在所述管线槽的第一侧面处的土方进行第二次开挖,以使所述管线槽的第一侧面全部露出,所述第一侧面是指所述管线槽靠近施工建筑的侧面;S3.在所述第二次开挖处的底部安装一垫层;S4.在所述管线槽的顶部和所述第一侧面,预埋钢板埋件并浇筑混凝土,形成一个整体的围护墙。该方法可以保护管线槽在建筑施工中不被损坏,同时提高了管线槽的稳定性和牢固性。 【EN】The invention provides a method for protecting an underground pipeline groove in building construction, which comprises the following steps: s1, excavating for the first time on earthwork at the top of a pipeline groove to enable the top of the pipeline groove to be completely exposed; s2, excavating earthwork at the first side face of the pipeline groove for the second time to enable the first side face of the pipeline groove to be completely exposed, wherein the first side face is the side face of the pipeline groove close to the construction building; s3, installing a cushion layer at the bottom of the second excavation position; and S4, embedding steel plate embedded parts and pouring concrete at the top of the pipeline groove and the first side face to form an integral enclosure wall. The method can protect the pipeline groove from being damaged in the building construction, and meanwhile, the stability and firmness of the pipeline groove are improved.
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申请号:201911325940.7 公开号:CN110995108A 主分类号:H02P23/14
申请人:【中文】阳光电源股份有限公司【EN】SUNGROW POWER SUPPLY Co.,Ltd. 申请日:2019.12.20 公开日:2020.04.10
摘要:【中文】本申请提供了旋变信号补偿方法、装置及旋转变压器,获取测得的原始转子角度信号中待补偿谐波的谐波信息。根据当前测得的角速度、上一采样周期补偿后的转子角度,以及待补偿谐波的谐波信息得到待补偿谐波的实际相位。进而根据待补偿谐波的实际相位和幅值得到待补偿谐波对应的待补偿角度。最后,依据各个待补偿谐波的待补偿角度对原始转子角度信号进行角度补偿,得到补偿后的转子角度信息,并作为电机的转子角度输入至下一级控制中。该方案针对测得的转子角度信号中包含的谐波分量进行补偿,得到补偿后的转子角度,从而抑制了转子角度信号中的谐波分量,进而避免谐波分量对电机控制系统造成影响,以便改善电机控制系统的性能。 【EN】The application provides a rotary transformer signal compensation method, a rotary transformer signal compensation device and a rotary transformer, and harmonic information of harmonic waves to be compensated in measured original rotor angle signals is obtained. And obtaining the actual phase of the harmonic to be compensated according to the currently measured angular velocity, the rotor angle compensated in the last sampling period and the harmonic information of the harmonic to be compensated. And then obtaining the angle to be compensated corresponding to the harmonic to be compensated according to the actual phase and amplitude of the harmonic to be compensated. And finally, carrying out angle compensation on the original rotor angle signal according to the angle to be compensated of each harmonic to be compensated to obtain the compensated rotor angle information, and inputting the compensated rotor angle information into the next-stage control as the rotor angle of the motor. The scheme compensates for the harmonic component contained in the measured rotor angle signal to obtain the compensated rotor angle, so that the harmonic component in the rotor angle signal is restrained, the influence of the harmonic component on a motor control system is avoided, and the performance of the motor control system is improved.
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申请号:201811157257.2 公开号:CN110968256A 主分类号:G06F3/06
申请人:【中文】华为技术有限公司【EN】HUAWEI TECHNOLOGIES Co.,Ltd. 申请日:2018.09.30 公开日:2020.04.07
摘要:【中文】一种数据处理方法及装置,该方法可包括:第一计算节点接收客户端发送的写入命令,所述第一计算节点根据范围分区算法的路由视图以及计算节点与文件的对应关系,确定所述第一数据对应的第一文件,所述第一计算节点将所述第一数据,存储至所述第一文件,所述第一计算节点根据所述计算节点与文件的对应关系,确定所述第一计算节点所对应的第二文件,所述第一计算节点获取除所述第一计算节点外的其它计算节点所存储的第二文件,所述第一计算节点存储所获取的所述其它计算节点的第二文件,采用本申请的方法可避免计算节点写入热点的问题,且保证读取数据的速率。 【EN】A data processing method and device can include: the method comprises the steps that a first computing node receives a write-in command sent by a client, the first computing node determines a first file corresponding to first data according to a routing view of a range partitioning algorithm and the corresponding relation between the computing node and the file, the first computing node stores the first data to the first file, the first computing node determines a second file corresponding to the first computing node according to the corresponding relation between the computing node and the file, the first computing node acquires the second files stored by other computing nodes except the first computing node, and the first computing node stores the acquired second files of the other computing nodes.
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申请号:201911391956.8 公开号:CN111044684A 主分类号:G01N33/00
申请人:【中文】潍柴动力股份有限公司【EN】Weichai Power Co.,Ltd. 申请日:2019.12.30 公开日:2020.04.21
摘要:【中文】本发明实施例提供一种氮氧传感器篡改的判断方法及设备,该方法在车辆进入预设工况后,对车辆的SCR箱下游的氮氧传感器测到的氮氧的值进行积分,获得第一氮氧积分值,其中,上述预设工况包括车辆的废气排温低于尿素的起喷温度,且车辆的转速在预设转速范围内,喷油量在预设喷油量范围内;并对SCR箱下游的理论氮氧输出值进行积分,获得第二氮氧积分值;进而,根据上述第一、第二氮氧积分值,判断车辆的氮氧传感器是否被篡改,其中,因为尿素没有达到起喷温度未执行喷射,下游的氮氧值近似的等于原始排放,因此如果氮氧传感器被篡改,上述第一氮氧积分值和第二氮氧积分值的差距就会较大,从而,有效诊断出氮氧传感器篡改行为。 【EN】The embodiment of the invention provides a method and equipment for judging tampering of a nitrogen-oxygen sensor, wherein the method comprises the steps of integrating nitrogen-oxygen values measured by the nitrogen-oxygen sensor at the downstream of an SCR (selective catalytic reduction) box of a vehicle after the vehicle enters a preset working condition to obtain a first nitrogen-oxygen integral value, wherein the preset working condition comprises that the exhaust temperature of exhaust gas of the vehicle is lower than the start-injection temperature of urea, the rotating speed of the vehicle is within a preset rotating speed range, and the oil injection amount is within a preset oil injection amount range; integrating theoretical nitrogen and oxygen output values at the downstream of the SCR tank to obtain a second nitrogen and oxygen integral value; further, it is judged whether the vehicle NOx sensor is tampered with or not based on the first and second NOx integrated values, wherein since urea does not reach the start-up temperature and injection is not performed, the downstream NOx value is approximately equal to the original emission, and therefore if the NOx sensor is tampered with, the difference between the first NOx integrated value and the second NOx integrated value is large, and therefore, the tampering behavior of the NOx sensor is effectively diagnosed.
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申请号:201911402045.0 公开号:CN111140318A 主分类号:F01N3/20
申请人:【中文】潍柴动力股份有限公司【EN】Weichai Power Co.,Ltd. 申请日:2019.12.30 公开日:2020.05.12
摘要:【中文】本发明实施例提供一种尿素解冻能力的诊断方法、装置、设备及存储介质,该方法通过在发动机达到预定工况后获取发动机在单位时间内产生的用于尿素解冻的第一热量;获取尿素箱中尿素完全解冻所需的第二热量;根据所述第一热量以及所述第二热量,获取解冻时间;当时间达到所述解冻时间时,诊断尿素是否解冻,并根据诊断结果进行故障提示。本实施例中通过考虑发动机产生用于尿素解冻的理论热量与尿素箱中尿素完全解冻理论所需热量之间的热量达到平衡时,释放诊断逻辑进行尿素解冻能力的诊断,能够准确反映尿素解冻能力是否正常,避免在解冻系统正常工作、而尿素尚未解冻就进行诊断导致报出错误,误导维修人员。 【EN】The embodiment of the invention provides a method, a device, equipment and a storage medium for diagnosing the unfreezing capability of urea, wherein the method comprises the steps of obtaining first heat for unfreezing the urea, which is generated by an engine in unit time, after the engine reaches a preset working condition; obtaining a second heat quantity required by complete thawing of urea in the urea box; obtaining defrosting time according to the first heat and the second heat; and when the time reaches the unfreezing time, diagnosing whether the urea is unfrozen, and prompting the fault according to the diagnosis result. When the theoretical heat that is used for urea thawing and the heat that urea in the urea case completely unfreezes theoretical need reach the equilibrium through considering the engine production in this embodiment, release diagnosis logic carries out the diagnosis of urea thawing capacity, can accurately reflect whether urea thawing capacity is normal, avoids normally working at the system that unfreezes, and urea is unfrozen just diagnoses and leads to reporting the mistake, misleading maintenance personal.
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申请号:201911154695.8 公开号:CN110912888A 主分类号:H04L29/06
申请人:【中文】上海交通大学【EN】SHANGHAI JIAO TONG University 申请日:2019.11.22 公开日:2020.03.24
摘要:【中文】本发明公开了一种基于深度学习的恶意HTTP流量检测系统和方法,涉及信息安全技术领域,包括域分割模块、主动标签矫正模块、多域特征提取模块,所述域分割模块将不同类别的字段分割成具有特定方法进行域分割的统一格式;所述主动标签矫正模块的主动标签矫正算法对标签进行矫正后存入数据库;所述多域特征提取模块挖掘HTTP协议中不同类型域之间的深层关系,通过所述主动标签矫正模块得到的数据进行训练学习,得到可信模型,通过本方案的实施,解决了如何利用字段交互和选择有效字段来描述HTTP流量的问题,减少了无效信息的负面影响而且突出了最重要的字段,同时也提高了框架的可解释性。 【EN】The invention discloses a malicious HTTP (hyper text transport protocol) traffic detection system and method based on deep learning, which relate to the technical field of information security and comprise a domain segmentation module, an active label correction module and a multi-domain feature extraction module, wherein the domain segmentation module segments different types of fields into a uniform format with a specific method for domain segmentation; an active label correction algorithm of the active label correction module corrects a label and then stores the corrected label into a database; the multi-domain feature extraction module excavates deep relationships among different types of domains in an HTTP (hyper text transport protocol), training and learning are carried out through data obtained by the active tag correction module to obtain a credible model, and by implementing the scheme, the problem of how to describe HTTP flow by using field interaction and selecting effective fields is solved, negative effects of invalid information are reduced, the most important fields are highlighted, and the interpretability of a framework is improved.
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申请号:201911328441.3 公开号:CN111182424A 主分类号:H04R9/06
申请人:【中文】歌尔股份有限公司【EN】GOERTEK Inc. 申请日:2019.12.20 公开日:2020.05.19
摘要:【中文】本发明公开了一种发声装置。所述发声装置包括:壳体组件,所述壳体组件配置为用于实现音圈与外部电路的连通;所述壳体组件包括导电件和壳体,所述导电件与壳体一体成型;音圈,所述壳体组件内形成容置空间,所述容置空间内设置有所述音圈;所述导电件包括第一导电部、第二导电部,以及与所述第一导电部和所述第二导电部分别固定连接的连接线;所述导电件的一端与所述音圈固定连接,另一端与外部电路固定连接。本发明发声装置中壳体与导电件一体成型形成壳体组件,降低了发声装置的装配难度。 【EN】The invention discloses a sound production device. The sound generating device includes: a housing assembly configured for enabling communication of the voice coil with external circuitry; the shell component comprises a conductive piece and a shell, and the conductive piece and the shell are integrally formed; the voice coil is arranged in the accommodating space; the conductive part comprises a first conductive part, a second conductive part and a connecting wire which is fixedly connected with the first conductive part and the second conductive part respectively; one end of the conductive piece is fixedly connected with the voice coil, and the other end of the conductive piece is fixedly connected with an external circuit. The shell and the conductive piece are integrally formed to form the shell assembly in the sound generating device, so that the assembly difficulty of the sound generating device is reduced.
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