当前查询到4条专利与查询词 "Zhang Chunkui"相关,搜索用时0.2968581秒!排序方式:
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申请号:202010042588.2 公开号:CN111150846A 主分类号:A61K45/00
摘要:【中文】本发明公开了属于生物医药领域的一种帕金森病治疗靶标及其应用。本发明证实了在PD小鼠模型中,STN下游核团还包括未被报道的丘脑前核,并证明在PD状态下ANT核团活性升高,抑制STN活性后ANT核团活性降低。同时证明,在PD状态下,SNT‑ANT突触连接强度增加,AMPAR亚型GluR1通过S845位点磷酸化上膜增加,通过短肽的抑制实验说明,ANT核团可以作为帕金森病治疗的一个靶点。 【EN】The invention discloses a Parkinson disease treatment target and application thereof, belonging to the field of biological medicines. The present invention confirms that the STN downstream nuclei also include non-reported thalamic pronuclei in a PD mouse model, and demonstrates that ANT nuclei activity is increased in a PD state and decreased after inhibition of STN activity. Meanwhile, the SNT-ANT synaptic connection strength is increased in a PD state, the AMPAR subtype GluR1 is increased through membrane phosphorylation at an S845 site, and an inhibition experiment of short peptides shows that an ANT nuclear group can be used as a target point for treating the Parkinson disease.
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申请号:201811194488.0 公开号:CN111127381A 主分类号:G06T7/00
摘要:【中文】本发明涉及受电弓异常检测技术领域,公开了一种受电弓滑板不平行检测方法。包括以下过程:实时输入不同类型的受电弓图像;通过高斯平滑的方法对受电弓图像进行滤波去噪处理;采用梯度计算去除垂直方向上的轮廓干扰,再进行形态学处理和纹理特征计算,提取到受电弓图像轮廓;筛除干扰直线,进行直线聚类判别,提取受电弓滑板图像;根据受电弓滑板图像获取滑板空间几何特征,判断滑板异常状态。发明的技术方案对光源不敏感,适用于不同光照情况;算法参数修改方便,非专业人员也可操作;现场适用性强,适用于多个不同现场情况下、不同类型受电弓的提取;检测正确率高,误检率、漏检率低。 【EN】The invention relates to the technical field of pantograph abnormity detection, and discloses a pantograph slide plate non-parallelism detection method. The method comprises the following steps: inputting different types of pantograph images in real time; filtering and denoising the pantograph image by a Gaussian smoothing method; removing contour interference in the vertical direction by adopting gradient calculation, performing morphological processing and texture feature calculation, and extracting the contour of the pantograph image; screening out interference straight lines, carrying out straight line clustering judgment, and extracting an image of the pantograph slide plate; and acquiring the space geometric characteristics of the slide plate according to the image of the pantograph slide plate, and judging the abnormal state of the slide plate. The technical scheme of the invention is insensitive to the light source and is suitable for different illumination conditions; the algorithm parameters are convenient to modify, and non-professional personnel can operate the algorithm parameters; the field applicability is strong, and the method is suitable for extracting different types of pantographs under different field conditions; the detection accuracy is high, and the false detection rate and the missing detection rate are low.
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申请号:201811194489.5 公开号:CN111127382A 主分类号:G06T7/00
摘要:【中文】本发明涉及铁路组件检测技术领域,公开了一种接触网悬挂组件_U型环备帽缺陷检测方法。具体包括以下过程:步骤1,相机采集接触网悬挂区域图像;步骤2,采用分类器检出U型环区域位置;步骤3,通过图像处理,根据备帽目标的形状特征,从U型环区域中提取备帽目标位置;步骤4,根据备帽各组件的位置关系或缺失有无状态判别备帽缺陷;步骤5,备帽缺陷状态检测结果作为U型环状态输出。本发明技术方案先采用粗定位快速检出U型环区域,再采用精准定位的策略,通过图像分析精准提取备帽目标,图像提取有效性高;采用组件状态分析方法实现备帽缺陷检测的方式快速、有效。 【EN】The invention relates to the technical field of railway component detection, and discloses a method for detecting defects of a U-shaped spare cap of a suspension component of a contact network. The method specifically comprises the following steps: step 1, a camera collects images of a suspension area of a contact network; step 2, detecting the position of the U-shaped ring area by adopting a classifier; step 3, extracting the position of the cap-prepared target from the U-shaped ring area through image processing according to the shape characteristics of the cap-prepared target; step 4, judging the defects of the spare cap according to the position relation or the missing state of each component of the spare cap; and 5, outputting a detection result of the defect state of the spare cap as the state of the U-shaped ring. According to the technical scheme, the U-shaped ring area is quickly detected by adopting coarse positioning, then the strategy of accurate positioning is adopted, the cap preparation target is accurately extracted through image analysis, and the image extraction effectiveness is high; the method for detecting the defects of the spare cap by adopting the component state analysis method is rapid and effective.
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申请号:201880054660.4 公开号:CN111052035A 主分类号:G06F1/20
申请人:【中文】三星电子株式会社【EN】Samsung Electronics Co.,Ltd. 申请日:2018.08.22 公开日:2020.04.21
摘要:【中文】提供了一种由电子装置执行的控制方法。所述控制方法包括:监测所述电子装置的多个部件中的每个部件的电流消耗,预测所述电子装置的第一表面温度并检测产生热量的位置,通过分析与所述产生热量的位置相对应的部件的功率消耗来预测第二表面温度,确定所预测的第二表面温度是否大于或等于预定温度,当所预测的第二表面温度大于或等于所述预定温度时设置目标温度,以及控制所述部件以降低所述功率消耗。 【EN】A control method performed by an electronic device is provided. The control method comprises the following steps: the method includes monitoring a current consumption of each of a plurality of components of the electronic device, predicting a first surface temperature of the electronic device and detecting a location of heat generation, predicting a second surface temperature by analyzing a power consumption of the component corresponding to the location of heat generation, determining whether the predicted second surface temperature is greater than or equal to a predetermined temperature, setting a target temperature when the predicted second surface temperature is greater than or equal to the predetermined temperature, and controlling the components to reduce the power consumption.
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