摘要：【中文】一种尼龙衬布伸缩卷轴，包括：卷轴支架，为两头贯穿的中空柱体，所述卷轴支架径向外壁上套设有至少两片支架环套，所述支架环套上设置有若干安装孔；若干伸缩轴，依次穿过所述相邻支架环套的安装孔，分布在所述卷轴支架的四周，所述伸缩轴与所述卷轴支架的轴线平行；若干伸缩卷筒片，为圆弧状的薄片，通过活动连接板组件连接于所述伸缩轴的外侧；所述活动连接板组件的一端可转动的连接于伸缩轴上，另一端可转动的连接于伸缩卷筒片上，所述活动连接板以连接于伸缩轴上的一端为圆心转动时，所述伸缩卷筒片向远离所述伸缩轴或靠近所述伸缩卷筒片方向移动。 【EN】A nylon-backed retractable reel comprising: the scroll support is a hollow cylinder with two ends penetrating through, at least two support ring sleeves are sleeved on the radial outer wall of the scroll support, and a plurality of mounting holes are formed in the support ring sleeves; the telescopic shafts sequentially penetrate through the mounting holes of the adjacent support ring sleeves and are distributed on the periphery of the scroll support, and the telescopic shafts are parallel to the axis of the scroll support; the plurality of telescopic reel pieces are arc-shaped thin pieces and are connected to the outer side of the telescopic shaft through a movable connecting plate assembly; one end of the movable connecting plate component is rotatably connected to the telescopic shaft, the other end of the movable connecting plate component is rotatably connected to the telescopic reel piece, and when the movable connecting plate rotates by taking one end connected to the telescopic shaft as a circle center, the telescopic reel piece moves towards the direction far away from the telescopic shaft or close to the telescopic reel piece.

摘要：【中文】本发明公开了一种预压组合立式钢筋混凝土盾构管片生产方法，包括以下步骤：将各模体移动至相应位置进行初步定位；各相邻模体之间设有模腔；将管片钢筋笼安放入各模体之间的模腔内；将各模体紧密贴合夹紧形成生产盾构管片的整体模具；向各模腔内浇筑满混凝土，在模腔顶部安装盖板封闭；通过加压装置对模腔内的混凝土加压，并保持恒定压力至混凝土终凝并达到相应强度；卸去通过加压装置对模腔内的混凝土施加的压力，对混凝土进行蒸养；当混凝土达到指定强度形成管片后，使各模体分离并对管片退模。本发明占地面积小，提高生产效率，改善管片表观质量，提高管片混凝土的力学性能、抗渗性及耐久性，提高整体稳定性。 【EN】The invention discloses a production method of a pre-pressed combined vertical reinforced concrete shield segment, which comprises the following steps: moving each die body to a corresponding position for preliminary positioning; a die cavity is arranged between every two adjacent die bodies; placing the segment reinforcement cage into a mold cavity between the mold bodies; tightly attaching and clamping all the die bodies to form an integral die for producing the shield segment; pouring concrete into each mold cavity, and installing a cover plate on the top of each mold cavity for sealing; pressurizing the concrete in the mold cavity by a pressurizing device, and keeping constant pressure until the concrete is finally set and reaches corresponding strength; the pressure applied to the concrete in the mould cavity by the pressurizing device is removed, and the concrete is steamed; and after the concrete reaches the specified strength to form the duct piece, separating each mould body and demoulding the duct piece. The invention has small occupied area, improves the production efficiency, improves the apparent quality of the duct piece, improves the mechanical property, impermeability and durability of duct piece concrete, and improves the overall stability.

摘要：【中文】本发明公开了一种靶向NKG2D配体和CD19的双靶点嵌合抗原受体及其表达载体和应用，属于肿瘤免疫药物领域。所述双靶点嵌合抗原受体包括：依次连接的信号肽、靶向NKG2D配体的NKG2D胞外区、连接片段、靶向CD19的单链抗体、加长的CD8α铰链区、跨膜区、共刺激因子和胞内信号肽，该双靶点嵌合抗原受体不仅能够特异性识别靶向NKG2D配体或CD19抗原这两个单个靶点表达的肿瘤细胞，还可以识别靶向NKG2D配体和CD19抗原共同表达的肿瘤细胞，该双靶点的CAR‑T具有更强的抗肿瘤活性，能够避免低丰度抗原表达的阳性肿瘤细胞产生免疫逃逸，从而降低了复发风险。 【EN】The double-target chimeric antigen receptor not only can specifically identify tumor cells expressing two single targets of a targeting NKG2D ligand or a CD19 antigen, but also can identify tumor cells jointly expressing the targeting NKG2D ligand and the CD19 antigen, and the CAR-T of the double-target has stronger anti-tumor activity, and can avoid the escape of positive tumor cells expressed by low-abundance antigens to generate immunity, thereby reducing the recurrence risk.

摘要：【中文】本发明公开了一种靶向CD19和CD20的双靶点嵌合抗原受体及其表达载体和应用，属于肿瘤免疫药物领域。所述双靶点嵌合抗原受体包括：依次连接的信号肽、靶向CD19的单链抗体、靶向CD20的单链抗体、CD8α铰链区、跨膜区、共刺激因子和胞内信号肽。该双靶点嵌合抗原受体包括：信号肽、靶向CD19的单链抗体、靶向CD20的单链抗体、加长的CD8α铰链区、跨膜区、共刺激因子和胞内信号肽，该双靶点嵌合抗原受体不仅能够特异性识别CD19抗原或CD20抗原这两个单个靶点表达的肿瘤细胞，还可以识别CD19抗原和CD20抗原共同表达的肿瘤细胞，该双靶点的CAR‑T具有更强的抗肿瘤活性，能够避免低丰度抗原表达的阳性肿瘤细胞产生免疫逃逸，从而降低了复发风险。 【EN】The invention discloses a double-target chimeric antigen receptor targeting CD19 and CD20, an expression vector and application thereof, belonging to the field of tumor immunity drugs, wherein the double-target chimeric antigen receptor comprises a signal peptide, a single-chain antibody targeting CD19, a single-chain antibody targeting CD20, a CD8 α hinge region, a transmembrane region, a co-stimulatory factor and an intracellular signal peptide which are sequentially connected.

摘要：【中文】本发明公开了一种分泌双特异性抗体的嵌合抗原受体及其表达载体和应用，属于肿瘤免疫药物领域。所述嵌合抗原受体包括：依次连接的信号肽、靶向CD19的单链抗体、加长的CD8α铰链区、跨膜区、共刺激因子、胞内信号肽、P2A连接肽、IL2信号肽、靶向CD20的单链抗体、靶向CD3的单链抗体和标签蛋白。该嵌合抗原受体为具备特异性靶向CD19阳性肿瘤细胞的同时还分泌靶向CD20和靶向CD3的双特异性抗体，这能够靶向和激活非传导的T细胞，从而靶向肿瘤抗原CD20，进而实现CAR‑T细胞在体内有效杀死B细胞系恶性血液肿瘤细胞的目的。同时，该嵌合抗原受体的T细胞能够避免低丰度表达的CD19阳性肿瘤细胞产生免疫逃逸，从而降低了B细胞系恶性血液肿瘤的复发风险。 【EN】The chimeric antigen receptor is a bispecific antibody which has specificity targeting CD19 positive tumor cells and also secretes targeting CD20 and targeting CD3, so that the chimeric antigen receptor can target and activate non-conductive T cells, thereby targeting a tumor antigen CD20, and further achieving the purpose of effectively killing B cell line malignant blood tumor cells in vivo by the CAR-T cells, and meanwhile, the T cells of the chimeric antigen receptor can avoid immune escape of the low-abundance expression CD19 positive tumor cells, thereby reducing the recurrence risk of the B cell line malignant blood tumor.

摘要：【中文】本发明涉及的是光纤通信材料制备技术领域，尤其是一种光纤预制棒熔融成型方法及其制造设备。包括塔架、端部密封装置、抽真空管路、石英砂填充管路、推进装置、加热炉、夹持牵引装置、光纤预制棒冷却装置和测径仪；加热炉安装在塔架上，推进装置安装在加热炉上部的塔架上，夹持装置安装在加热炉下部，光纤预制棒冷却装置安装在夹持装置下部；端部密封装置安装在石英套管上端部，端部密封装置上配有抽真空管路及石英砂填充管路，分别用于对石英套管内抽真空及向石英套管内填充高纯度石英砂；加热炉出口处下部装有测径仪，测径仪通过传感器，测量控制拉制光纤预制棒外径。 【EN】The invention relates to the technical field of optical fiber communication material preparation, in particular to a fusion molding method of an optical fiber preform and manufacturing equipment thereof. The device comprises a tower frame, an end sealing device, a vacuumizing pipeline, a quartz sand filling pipeline, a propelling device, a heating furnace, a clamping and traction device, an optical fiber perform cooling device and a diameter measuring instrument; the heating furnace is arranged on the tower, the propelling device is arranged on the tower on the upper part of the heating furnace, the clamping device is arranged on the lower part of the heating furnace, and the optical fiber perform cooling device is arranged on the lower part of the clamping device; the end sealing device is arranged at the upper end part of the quartz sleeve and is provided with a vacuumizing pipeline and a quartz sand filling pipeline which are respectively used for vacuumizing the quartz sleeve and filling high-purity quartz sand into the quartz sleeve; the lower part of the outlet of the heating furnace is provided with a diameter measuring instrument which measures and controls the outer diameter of the drawn optical fiber preform through a sensor.

摘要：【中文】本发明公开了一种推荐服务的实验及其管理方法、装置和系统。该实验方法包括：在模拟线上环境中部署用于推荐目标服务的更新实验；在所述模拟线上环境中进行基于真实线上流量信息的流量回放，以获取针对更新实验的更新实验指标；以及基于所述更新实验指标，确定是否上线所述更新实验。由此，通过针对同一推荐服务的后续实验进行模拟线上环境的回归测试，能够在后续实验上线前找出推荐服务本身的潜在问题，从而避免不必要的上线，提升实验效率并确保用户体验。 【EN】The invention discloses an experiment of recommended service and a management method, a device and a system thereof. The experimental method comprises the following steps: deploying an update experiment for recommending a target service in a simulated online environment; performing flow playback based on real online flow information in the simulated online environment to obtain an updated experiment index for an updated experiment; and determining whether to go online based on the update experiment index. Therefore, the regression test of the on-line environment is simulated for the follow-up experiment of the same recommendation service, the potential problem of the recommendation service can be found out before the follow-up experiment is on line, unnecessary on-line is avoided, the experiment efficiency is improved, and the user experience is ensured.

摘要：【中文】本发明公开了一种办公室行政管理用多功能文件存放装置，包括柜体，所述柜体的底部固定连接有支撑板，所述支撑板的底部固定连接有支撑块，所述柜体的侧面固定连接有合页，所述合页的侧面固定连接有柜门，所述柜门的背面固定连接有把手，所述柜门的正面开设有方孔，所述方孔的内壁固定连接有透明PC板，所述方孔的内顶壁固定连接有第一横条，所述第一横条的下表面固定连接有折叠布，所述折叠布的下表面固定连接有第二横条。该办公室行政管理用多功能文件存放装置，通过设置柜体、支撑板、支撑块、合页、柜门、把手、方孔、透明PC板、第一横条、折叠布、第二横条和活动块，从而达到该办公室行政管理用多功能文件存放装置具有便于保护文件的效果。 【EN】The invention discloses a multifunctional file storage device for office administrative management, which comprises a cabinet body, wherein the bottom of the cabinet body is fixedly connected with a supporting plate, the bottom of the supporting plate is fixedly connected with a supporting block, the side surface of the cabinet body is fixedly connected with a hinge, the side surface of the hinge is fixedly connected with a cabinet door, the back surface of the cabinet door is fixedly connected with a handle, the front surface of the cabinet door is provided with a square hole, the inner wall of the square hole is fixedly connected with a transparent PC plate, the inner top wall of the square hole is fixedly connected with a first cross bar, the lower surface of the first cross bar is fixedly connected with folding cloth, and the lower surface of the folding cloth is fixedly connected with a second cross bar. This multi-functional file strorage device is used in office administrative management through setting up the cabinet body, backup pad, supporting shoe, hinge, cabinet door, handle, square hole, transparent PC board, first horizontal bar, folding cloth, second horizontal bar and movable block to reach this multi-functional file strorage device is used in office administrative management and have the effect of the protection file of being convenient for.

摘要：【中文】本发明公开了一种闹钟设置方法、电子设备及存储介质。该方法应用于蓝牙设备时，包括：接收用户闹钟设置的语音，将所述语音发送至智能终端；接收所述智能终端发送的基于所述语音解析成的闹钟设置指令；基于所述闹钟设置指令设置本地闹钟。该方法应用于智能终端时，包括：接收用户闹钟设置的语音；将所述语音解析成对应的闹钟设置指令，并将所述闹钟设置指令发送至蓝牙设备。该方法可以在不具有语音解析功能的蓝牙设备上设置本地闹钟，可以节省蓝牙设备的成本，设置闹钟方式简便，丰富了闹钟设置类型，用户体验好。 【EN】The invention discloses an alarm clock setting method, electronic equipment and a storage medium. When the method is applied to the Bluetooth equipment, the method comprises the following steps: receiving voice set by a user alarm clock, and sending the voice to an intelligent terminal; receiving an alarm clock setting instruction which is sent by the intelligent terminal and analyzed based on the voice; and setting a local alarm clock based on the alarm clock setting instruction. When the method is applied to the intelligent terminal, the method comprises the following steps: receiving voice set by a user alarm clock; and analyzing the voice into a corresponding alarm clock setting instruction, and sending the alarm clock setting instruction to the Bluetooth equipment. The method can set the local alarm clock on the Bluetooth equipment without the voice analysis function, can save the cost of the Bluetooth equipment, has simple and convenient alarm clock setting mode, enriches the alarm clock setting types and has good user experience.

摘要：【中文】本发明公开了基于深度卷积神经网络的番茄病害识别方法，本发明采用深度神经网络Residual 56Attention，ResNet通过残差学习解决了深度网络的退化问题，以训练出更深的网络的同时节省了大量资源占用。Residual 56Attention在ResNet基础上引入了Attention机制，逐渐提取高层特征并增大模型的感受野，高层特征的激活对应位置能够反映attention的区域，然后再对这种具有attention特征的feature map进行上采样，使其大小回到原始feature map的大小，就将attention对应到原始图片的每一个位置上。在原有的Residual 56Attention网络基础上所有的激活函数层均使用ELU函数作为激活函数，在样本识别时运算效率更高，而模型参数减少，收敛速度更快，降低了资源的占用，以及对软硬件的高需求，可以更好投入到实际使用。 【EN】The invention discloses a tomato disease identification method based on a deep convolutional neural network, which adopts a deep neural network Residual56 attachment, and ResNet solves the degradation problem of the deep neural network through Residual learning so as to train a deeper network and save a large amount of resource occupation. The resolution 56 attribute introduces an attribute mechanism on the basis of ResNet, gradually extracts high-level features and increases the receptive field of a model, the corresponding positions of the high-level features can reflect the regions of attributes, then the feature map with the attributes is up-sampled, the size of the feature map returns to the size of the original feature map, and the attributes are corresponding to each position of the original picture. On the basis of the original Residual56Attention network, all activation function layers use an ELU function as an activation function, the calculation efficiency is higher during sample identification, model parameters are reduced, the convergence speed is higher, the occupation of resources is reduced, and the high requirements on software and hardware can be better put into practical use.