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1:
[发明]
【中文】一种纳米等离子体光谱技术 【EN】Nano plasma spectrum technology
申请号:
201911121855.9
公开号:CN110954510A 主分类号:G01N21/552
申请人:
【中文】温州森佰生物科技有限公司【EN】WENZHOU SENBAI BIOTECHNOLOGY Co.,Ltd.
申请日:2019.11.15 公开日:2020.04.03
发明人:
【中文】王毅
;
张庆文【EN】Wang Yi
;
Zhang Qingwen
摘要:【中文】本发明公开了一种纳米等离子体光谱技术,该光谱技术包括:局域型表面等离子体共振(LSPR)超阵列芯片、光电探测器和计算模块;待测光照射至LSPR超阵列芯片上,经过芯片上不同位置的各个所述透射单元吸收过滤后,被光电探测器在相对应的位置上采集,通过计算模块对不同位置的光强度数据集进行记录,并通过算法重建待测光的光谱。本发明中的方法能够调节探测的光谱分辨率和光谱范围,不依赖于传统的色散光学器件,从而达到在体积变小的同时提高光谱分辨率和检测范围的效果,结构设计非常简单。由于LSPR芯片加工制备的工业化程度非常高,化学稳定性好,非常适合批量生产和广泛应用,成本也因此得到大幅降低。 【EN】The invention discloses a nano plasma spectrum technology, which comprises the following steps: the device comprises a Local Surface Plasmon Resonance (LSPR) super array chip, a photoelectric detector and a calculation module; the light to be measured is irradiated on the LSPR super-array chip, is absorbed and filtered by the transmission units at different positions on the chip and is collected by the photoelectric detector at corresponding positions, the light intensity data sets at different positions are recorded by the calculation module, and the spectrum of the light to be measured is reconstructed by an algorithm. The method can adjust the spectral resolution and spectral range of detection without depending on the traditional dispersive optical device, thereby achieving the effect of improving the spectral resolution and the detection range while the volume is reduced, and the structural design is very simple. The LSPR chip has high industrialization degree and good chemical stability, is very suitable for batch production and wide application, and greatly reduces the cost.
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2:
[发明]
【中文】一种氘代骨化三醇的制备方法、及其中间体 【EN】Preparation method of deuterated calcitriol and intermediate thereof
申请号:
201811045167.4
公开号:CN110885304A 主分类号:C07C401/00
申请人:
【中文】上海医药工业研究院
;
中国医药工业研究总院【EN】SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY
;
China State Institute of Pharmaceutical Industry
申请日:2018.09.07 公开日:2020.03.17
发明人:
【中文】张庆文
;
齐丽春
;
张德杰【EN】
Zhang Qingwen
;
Qi Lichun
;
Zhang Dejie
摘要:【中文】本发明公开了一种氘代骨化三醇的制备方法、及其中间体。本发明提供了一种如式DG‑1所示的氘代骨化三醇的制备方法,其包括如下步骤:步骤(1)、在有机溶剂1中,在脱保护剂作用下,将如式II所示的化合物进行如下所示的脱羟基保护基反应,得到如式DG‑4所示的化合物即可;步骤(2)、在有机溶剂2中,在光照射和光敏剂存在下,将步骤(1)中所述的如式DG‑4所示的化合物进行如下所示的光异构化反应,得到所述的如式DG‑1所示的氘代骨化三醇即可;其中,R
1
为羟基保护基。采用本发明的中间体的氘代骨化三醇制备方法,起始原料易得、合成路线短、操作简便、收率高。
【EN】The invention discloses a preparation method of deuterated calcitriol and an intermediate thereof. The invention provides a preparation method of deuterated calcitriol shown as a formula DG-1, which comprises the following steps: step (1), carrying out a dehydroxylation protecting group reaction on a compound shown as a formula II in an organic solvent 1 under the action of a deprotection agent to obtain a compound shown as a formula DG-4; step (2), in an organic solvent 2, under the conditions of light irradiation and the existence of a photosensitizer, carrying out photoisomerization reaction on the compound shown as the formula DG-4 in the step (1) as shown in the specification to obtain deuterated calcitriol shown as the formula DG-1; wherein R is
1
Is a hydroxyl protecting group. The preparation method of the intermediate deuterated calcitriol has the advantages of easily available starting materials, short synthetic route, simple and convenient operation and high yield.
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3:
[发明]
【中文】一种设备接入控制方法及设备接入组件 【EN】Equipment access control method and equipment access assembly
申请号:
201811121108.0
公开号:CN110943968A 主分类号:H04L29/06
申请人:
【中文】杭州海康威视系统技术有限公司【EN】HANGZHOU HIKVISION SYSTEM TECHNOLOGY Co.,Ltd.
申请日:2018.09.25 公开日:2020.03.31
发明人:
【中文】张清文
;
张伟
;
王兆俊【EN】
Zhang Qingwen
;
Zhang Wei
;
Wang Zhaojun
摘要:【中文】本申请提供一种设备接入控制方法及设备接入组件,该设备接入组件包括服务模块和驱动模块,所述服务模块与所述驱动模块对应不同的进程,且各进程相互独立;其中:所述服务模块,用于为上层应用提供服务入口,并根据上层应用的访问请求对驱动模块进行管理;所述驱动模块,用于通过驱动实例进行设备接入;其中,不同类型的设备对应不同的驱动模块;所述服务模块,还用于当驱动模块中已创建的驱动实例已接入设备的数量均达到预设单实例最大支持设备数时,在该驱动模块中创建新的驱动实例。该方法可以提高设备接入的稳定性,并提高单设备接入组件的设备接入能力。 【EN】The application provides a device access control method and a device access assembly, wherein the device access assembly comprises a service module and a drive module, the service module and the drive module correspond to different processes, and the processes are independent; wherein: the service module is used for providing a service entrance for the upper application and managing the drive module according to the access request of the upper application; the driving module is used for accessing equipment through a driving example; wherein, different types of equipment correspond to different driving modules; and the service module is also used for creating a new drive instance in the drive module when the number of the created drive instances in the drive module, which have access to the equipment, reaches the preset maximum number of the single instance supporting equipment. The method can improve the stability of equipment access and improve the equipment access capability of a single equipment access assembly.
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4:
[发明]
【中文】用于动态抓点的芯片失效分析的方法 【EN】Chip failure analysis method for dynamic grab point
申请号:
202010069875.2
公开号:CN111273152A 主分类号:G01R31/28
申请人:
【中文】上海华虹宏力半导体制造有限公司【EN】Shanghai Huahong Grace Semiconductor Manufacturing Corp.
申请日:2020.01.19 公开日:2020.06.12
发明人:
【中文】张雨田
;
曾志敏
;
张庆文【EN】Zhang Yutian
;
Zeng Zhimin
;
Zhang Qingwen
摘要:【中文】本申请公开了一种用于动态抓点的芯片失效分析的方法,涉及芯片失效分析领域。该方法包括将待测芯片安装在PCB板上,所述PCB板上至少设置有芯片连接座、电池和芯片引脚插针;将所述待测芯片通过所述PCB板上的引脚插针与测试机连接;将所述测试机、所述待测芯片与所述电池连接;通过所述测试机向所述待测芯片发送激励模式,所述激励模式用于令所述待测芯片进入预定激发状态中的一种;断开所述测试机与所述待测芯片、所述PCB板的连接;解决了目前进行动态抓点时需要搬动测试机的问题;达到了避免搬动测试机台,不限制测试机的位置,维持芯片状态方便进行动态抓点的效果。 【EN】The application discloses a chip failure analysis method for dynamic grab points, and relates to the field of chip failure analysis. The method comprises the steps that a chip to be tested is installed on a PCB, and a chip connecting seat, a battery and a chip pin contact pin are at least arranged on the PCB; connecting the chip to be tested with a testing machine through a pin contact pin on the PCB; connecting the tester and the chip to be tested with the battery; sending an excitation mode to the chip to be tested through the testing machine, wherein the excitation mode is used for enabling the chip to be tested to enter one of preset excitation states; disconnecting the connection between the tester and the chip to be tested and the PCB; the problem that the test machine needs to be moved when the dynamic point grabbing is carried out at present is solved; the effects of avoiding moving the test machine, not limiting the position of the test machine and maintaining the state of the chip to conveniently carry out dynamic point grabbing are achieved.
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5:
[发明]
【中文】一种高性能碳纳米管纱线及其制备方法 【EN】High-performance carbon nanotube yarn and preparation method thereof
申请号:
201810982223.0
公开号:CN110857478A 主分类号:D02G3/40
申请人:
【中文】中国科学院苏州纳米技术与纳米仿生研究所【EN】SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS (SINANO), CHINESE ACADEMY OF SCIENCES
申请日:2018.08.27 公开日:2020.03.03
发明人:
【中文】张骁骅
;
赵静娜
;
李清文【EN】Zhang Xiaohua
;
Zhao Jingna
;
Li Qingwen
摘要:【中文】本发明公开了一种高性能碳纳米管纱线及其制备方法。所述制备方法包括:使两根以上碳纳米管纤维进入一通孔,并沿长度方向牵拉该两根以上碳纳米管纤维,使该两根以上碳纳米管纤维从所述通孔内连续通过,从而使该两根以上碳纳米管纤维被拉伸直且被所述通孔挤压收缩并同时充分浸润功能性高分子的溶液,形成一整体纱线。本发明未采用传统纺纱加捻方式,避免了加捻对碳纳米管纤维前期的强力损伤以及加捻造成纱线结构的不均匀性,减少纱线强力弱环;所制备纱线中纤维间界面结合力增强,纤维断裂的同时性提高,纤维强力利用率提高,且具有高强力及良好的柔韧性、热稳定性和耐摩擦性能。 【EN】The invention discloses a high-performance carbon nanotube yarn and a preparation method thereof. The preparation method comprises the following steps: more than two carbon nanotube fibers enter a through hole, and are pulled along the length direction to continuously pass through the through hole, so that the more than two carbon nanotube fibers are stretched straight and are extruded and shrunk by the through hole, and simultaneously, the functional polymer solution is fully infiltrated to form the integral yarn. The invention does not adopt the traditional spinning twisting mode, avoids the early-stage strength damage of the carbon nano tube fiber caused by twisting and the nonuniformity of the yarn structure caused by twisting, and reduces the weak rings of the yarn strength; the interface bonding force between fibers in the prepared yarn is enhanced, the fiber breakage simultaneity is improved, the fiber strength utilization rate is improved, and the yarn has high strength, good flexibility, thermal stability and friction resistance.
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6:
[发明]
【中文】一种治疗高脂血症的中药组合物 【EN】Traditional Chinese medicine composition for treating hyperlipidemia
申请号:
201811367558.8
公开号:CN111195310A 主分类号:A61K36/884
申请人:
【中文】鲁南制药集团股份有限公司【EN】Lunan Pharmaceutical Group Corp.
申请日:2018.11.16 公开日:2020.05.26
发明人:
【中文】张贵民
;
马庆文
;
程国良【EN】Zhang Guimin
;
Ma Qingwen
;
Cheng Guoliang
摘要:【中文】本发明属于中医药领域,具体涉及一种中药组合物在制备治疗高脂血症药物中的用途,所述中药组合物主要由山楂、泽泻、茵陈、大黄、决明子、小蓟、苍术、白术、猪苓、柴胡、甘草制备而成。本发明中药组合物中各味药符合君臣佐使配伍原则,配伍科学,切中病例,可明显改善临床症状,有效治疗高脂血症,尤其针对肝肾阴虚型高脂血症,治疗有效率可达90%以上。 【EN】The invention belongs to the field of traditional Chinese medicines, and particularly relates to application of a traditional Chinese medicine composition in preparation of a medicine for treating hyperlipidemia. The traditional Chinese medicine composition provided by the invention has the advantages that all the medicines conform to the monarch, minister, assistant and guide compatibility principle, the compatibility is scientific, the disease is hit, the clinical symptoms can be obviously improved, the hyperlipidemia can be effectively treated, and particularly, the effective rate of treatment for the liver-kidney yin deficiency type hyperlipidemia can reach more than 90%.
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7:
[发明]
【中文】可跨障机器人及可跨障机器人的跨障方法 【EN】Obstacle-surmountable robot and obstacle-surmountable method thereof
申请号:
202010085982.4
公开号:CN111267793A 主分类号:B60S9/215
申请人:
【中文】北京眸视科技有限公司【EN】BEIJING ELITENECT TECHNOLOGIES Co.,Ltd.
申请日:2020.02.11 公开日:2020.06.12
发明人:
【中文】王庆文
;
颜之婷
;
张晨光【EN】Wang Qingwen
;
Yan Zhiting
;
Zhang Chenguang
摘要:【中文】本发明涉及一种可跨障机器人及可跨障机器人的跨障方法,涉及机器人技术领域,可跨障机器人,包括车体、支撑组件以及第一行走轮;支撑组件至少有三组,多组支撑组件均安装于车体,并沿车体的行进方向间隔设置,每组支撑组件的驱动端均安装有第一行走轮;至少两组支撑组件能够驱动相应第一行走轮远离车体,以抬高车体,其余支撑组件能够驱动相应第一行走轮靠近车体,以跨过障碍。缓解了现有技术中的机器人容易因遇到障碍而无法动弹,进而影响正常工作的技术问题。 【EN】The invention relates to an obstacle-striding robot and an obstacle-striding method thereof, relating to the technical field of robots, wherein the obstacle-striding robot comprises a vehicle body, a support assembly and a first travelling wheel; the supporting assemblies are at least three groups, the multiple groups of supporting assemblies are all arranged on the vehicle body and are arranged at intervals along the advancing direction of the vehicle body, and the driving end of each group of supporting assemblies is provided with a first travelling wheel; at least two sets of support assemblies are capable of driving the respective first road wheels away from the vehicle body to raise the vehicle body, and the remaining support assemblies are capable of driving the respective first road wheels towards the vehicle body to cross an obstacle. The technical problem that the robot in the prior art cannot move and bounce easily due to the fact that the robot encounters obstacles, and normal work is influenced is solved.
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8:
[发明]
【中文】一种连续制备金属型单壁碳纳米管纤维的方法 【EN】Method for continuously preparing metal type single-walled carbon nanotube fiber
申请号:
201811032216.0
公开号:CN110878433A 主分类号:D01F9/12
申请人:
【中文】中国科学院苏州纳米技术与纳米仿生研究所【EN】SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS (SINANO), CHINESE ACADEMY OF SCIENCES
申请日:2018.09.05 公开日:2020.03.13
发明人:
【中文】杨名
;
张慧超
;
张永毅
;
李清文【EN】Yang Ming
;
Zhang Huichao
;
Zhang Yongyi
;
Li Qingwen
摘要:【中文】本发明公开了一种连续制备金属型单壁碳纳米管纤维的方法,包括:采用浮动催化化学气相沉积方法连续合成金属型单壁碳纳米管,进而获得金属型单壁碳纳米管宏观聚集体的第一步骤,将所述金属型单壁碳纳米管宏观聚集体纤维化而获得金属型单壁碳纳米管纤维的第二步骤;所述的第一步骤包括将原料输入反应区的步骤以及在反应区内合成金属型单壁碳纳米管的步骤,所述将原料输入反应区的步骤中,采用的原料包括高熔点金属催化剂和液态碳源,所述高熔点金属催化剂所含的金属元素包括钨、钴或镍。本发明的方法直接简便,连续性好,可控易操作,安全性好;所获金属型单壁碳纳米管纤维具有较高的电导率,较强的力学性能和结晶度,应用前景广泛。 【EN】The invention discloses a method for continuously preparing metal type single-walled carbon nanotube fibers, which comprises the following steps: a first step of continuously synthesizing metal type single-walled carbon nanotubes by adopting a floating catalytic chemical vapor deposition method to further obtain a macroscopic aggregate of the metal type single-walled carbon nanotubes, and a second step of fiberizing the macroscopic aggregate of the metal type single-walled carbon nanotubes to obtain metal type single-walled carbon nanotube fibers; the first step comprises a step of inputting raw materials into a reaction zone and a step of synthesizing the metal type single-walled carbon nanotube in the reaction zone, wherein the raw materials adopted in the step of inputting the raw materials into the reaction zone comprise a high-melting-point metal catalyst and a liquid carbon source, and metal elements contained in the high-melting-point metal catalyst comprise tungsten, cobalt or nickel. The method is direct, simple and convenient, good in continuity, controllable, easy to operate and good in safety; the obtained metal type single-walled carbon nanotube fiber has high conductivity, high mechanical property and crystallinity and wide application prospect.
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9:
[发明]
【中文】一种有杯沿的反应杯的加载装置 【EN】Loading device of reaction cup with cup edge
申请号:
201811159389.9
公开号:CN110967516A 主分类号:G01N35/04
申请人:
【中文】深圳传世生物医疗有限公司【EN】SHENZHEN THISTORY BIO-MEDICAL Co.,Ltd.
申请日:2018.09.30 公开日:2020.04.07
发明人:
【中文】张华利
;
张华伟
;
肖清文
;
尹桥波【EN】Zhang Huali
;
Zhang Huawei
;
Xiao Qingwen
;
Yin Qiaobo
摘要:【中文】本发明适用于体外诊断设备技术领域,提供了一种有杯沿的反应杯加载装置,包括:盛放有杯沿反应杯的腔体;至少含有一段具有第一倾斜角度和第二倾斜角度特征的静态轨道,自动调整反应杯的状态和自动清除无序反应杯;一个推送机构,其可以将反应杯从腔体的低处送达高处轨道。本发明的有杯沿的反应杯加载装置,为生物样本分析仪器的全自动化运行提供保障,深度利用了反应杯的特征以及其在轨道内变化及运动规律,采用了多角度静态轨道配合推送机构的简洁、高效配合,实现了反应杯的加载功能,整体结构紧凑、运行控制简单,大幅降低了机械复杂性和加工成本。 【EN】The invention is suitable for the technical field of in-vitro diagnostic equipment, and provides a reaction cup loading device with a cup edge, which comprises: a cavity for holding the cup edge reaction cup; the reaction cup device at least comprises a section of static track with the characteristics of a first inclination angle and a second inclination angle, and is used for automatically adjusting the state of the reaction cup and automatically clearing the disordered reaction cup; a pushing mechanism which can convey the reaction cup from the lower part of the cavity to the upper track. The reaction cup loading device with the cup edge provides guarantee for the full-automatic operation of a biological sample analyzer, deeply utilizes the characteristics of the reaction cup and the change and motion rule of the reaction cup in the track, adopts the simple and efficient matching of the multi-angle static track and the pushing mechanism, realizes the loading function of the reaction cup, has compact integral structure and simple operation control, and greatly reduces the mechanical complexity and the processing cost.
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10:
[发明]
【中文】二维永磁阵列式磁悬浮重力补偿器 【EN】Two-dimensional permanent magnet array type magnetic suspension gravity compensator
申请号:
201911236830.3
公开号:CN110880888A 主分类号:H02N15/00
申请人:
【中文】哈尔滨工业大学【EN】HARBIN INSTITUTE OF TECHNOLOGY
申请日:2019.12.05 公开日:2020.03.13
发明人:
【中文】张赫
;
寇宝泉
;
周立山
;
葛庆稳
;
曹广旭【EN】Zhang He
;
Kou Baoquan
;
Zhou Lishan
;
Ge Qingwen
;
Cao Guangxu
摘要:【中文】二维永磁阵列式磁悬浮重力补偿器,属于磁悬浮技术领域,本发明为解决大型载荷非接触支撑采用悬吊方式或气浮方式进行重力卸载,存在寄生力大、系统结构复杂的问题。本发明包括定子和动子,定子包括上层定子和下层定子,相互平行且固定连接的上层定子和下层定子之间设置动子,两层定子和动子之间存在垂向气隙;两层定子和动子均为N×N个矩形永磁体构成的二维阵列平板结构,每层平板结构中任意相邻两个永磁体之间存在间隔;永磁体充磁方向为垂向,每层平板结构中任意相邻两个永磁体的充磁方向相反;上层定子和下层定子相对位置永磁体的充磁方向相反;动子与上层定子相对位置永磁体的充磁方向相同。 【EN】The invention discloses a two-dimensional permanent magnet array type magnetic suspension gravity compensator, belongs to the technical field of magnetic suspension, and aims to solve the problems of large parasitic force and complex system structure in the gravity unloading of large-scale load non-contact support in a suspension mode or an air floatation mode. The invention comprises a stator and a rotor, wherein the stator comprises an upper layer stator and a lower layer stator, the rotor is arranged between the upper layer stator and the lower layer stator which are parallel to each other and fixedly connected, and a vertical air gap is formed between the two layers of stators and the rotor; the two layers of stators and the rotor are both of a two-dimensional array flat plate structure formed by N multiplied by N rectangular permanent magnets, and a space is reserved between any two adjacent permanent magnets in each layer of flat plate structure; the magnetizing directions of the permanent magnets are vertical, and the magnetizing directions of any two adjacent permanent magnets in each layer of flat plate structure are opposite; the magnetizing directions of the permanent magnets at the relative positions of the upper stator and the lower stator are opposite; the magnetizing directions of the permanent magnets at the relative positions of the rotor and the upper-layer stator are the same.
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