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1:
[发明]
【中文】一种口服葛根素混合胶束制剂、制备方法及应用 【EN】Oral puerarin mixed micelle preparation, preparation method and application
申请号:
201911090263.5
公开号:CN110934827A 主分类号:A61K9/107
申请人:
【中文】江西中医药大学【EN】JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
申请日:2019.11.08 公开日:2020.03.31
发明人:
【中文】朱卫丰
;
吴文婷
;
李文栋
;
邹钊
;
徐玲霞【EN】Zhu Weifeng
;
Wu Wenting
;
Li Wendong
;
Zou Zhao
;
Xu Lingxia
摘要:【中文】本发明涉及一种口服葛根素混合胶束制剂、制备方法及其应用,该混合胶束制剂包括葛根素以及载体材料,所述载体材料由聚氧乙烯‑聚氧丙烯‑聚氧乙烯三嵌段聚合物与聚乙二醇羟基硬脂酸酯通过自组装的方式构成,所述葛根素与所述载体材料的质量比为(16:9)~(20:10)。本发明制备得到的口服葛根素混合胶束制剂,不仅可有效提高药葛根素的溶解度以及载药稳定性,并且能通过改善膜流动性以实现促渗的功能,进而提高葛根素的口服生物利用度。 【EN】The invention relates to an oral puerarin mixed micelle preparation, a preparation method and application thereof, wherein the mixed micelle preparation comprises puerarin and a carrier material, the carrier material is formed by a polyoxyethylene-polyoxypropylene-polyoxyethylene triblock polymer and polyethylene glycol hydroxystearate in a self-assembly mode, and the mass ratio of the puerarin to the carrier material is (16:9) - (20: 10). The oral puerarin mixed micelle preparation prepared by the invention not only can effectively improve the solubility and the drug-loading stability of the puerarin, but also can realize the function of promoting infiltration by improving the membrane fluidity, thereby improving the oral bioavailability of the puerarin.
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2:
[发明]
【中文】电石干法生产乙炔工艺中含乙炔电石渣尾气处理系统 【EN】System for treating tail gas containing acetylene carbide slag in process of producing acetylene by calcium carbide dry method
申请号:
201911352474.1
公开号:CN110982554A 主分类号:C10H21/00
申请人:
【中文】中国成达工程有限公司【EN】CHINA CHENGDA ENGINEERING Co.,Ltd.
申请日:2019.12.25 公开日:2020.04.10
发明人:
【中文】刘斌
;
周军元
;
黄泽茂
;
赵文婷【EN】Liu Bin
;
Zhou Junyuan
;
Huang Zemao
;
Zhao Wenting
摘要:【中文】本发明公开了电石干法生产乙炔工艺中含乙炔电石渣尾气处理系统,解决现有技术尾气处理效率低、以及处理过程中存在安全隐患的技术问题。本发明包括从电石渣尾气源接出的除尘器,从除尘器接出的储热式焚烧炉,从储热式焚烧炉接出的热风引风机,从储热式焚烧炉接出的常温引风机,从常温引风机接出的尾气外排烟窗;热风引风机的出风口接入除尘器的进口,储热式焚烧炉接入有天然气供给管。本发明结构简单、设计科学合理,使用方便,采用蓄热式焚烧设备对含乙炔电石渣尾气进行焚烧处理,利用电石渣尾气中的乙炔燃烧产生的热量维持系统焚烧运行,实现尾气高效处理、系统低成本运行、以及节能环保安全排放尾气的目的。 【EN】The invention discloses a system for treating tail gas containing acetylene carbide slag in a process for producing acetylene by a calcium carbide dry method, which solves the technical problems of low tail gas treatment efficiency and potential safety hazard in the treatment process in the prior art. The invention comprises a dust remover connected from a carbide slag tail gas source, a heat storage type incinerator connected from the dust remover, a hot air induced draft fan connected from the heat storage type incinerator, a normal temperature induced draft fan connected from the heat storage type incinerator, and a tail gas exhaust smoke window connected from the normal temperature induced draft fan; the air outlet of the hot air draught fan is connected with the inlet of the dust remover, and the heat storage type incinerator is connected with a natural gas supply pipe. The tail gas incineration system is simple in structure, scientific and reasonable in design and convenient to use, adopts heat accumulating type incineration equipment to incinerate the acetylene-containing carbide slag tail gas, maintains the incineration operation of the system by using the heat generated by the combustion of acetylene in the carbide slag tail gas, and achieves the purposes of high-efficiency treatment of the tail gas, low-cost operation of the system, energy conservation, environmental protection and safe emission of the tail gas.
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3:
[发明]
【中文】基于仿生超滑表面的防污钛合金材料、其制备方法及应用 【EN】Antifouling titanium alloy material based on bionic super-smooth surface, and preparation method and application thereof
申请号:
201811127292.X
公开号:CN110952124A 主分类号:C25D11/26
申请人:
【中文】中国科学院宁波材料技术与工程研究所【EN】NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES
申请日:2018.09.27 公开日:2020.04.03
发明人:
【中文】赵文杰
;
王艳君
;
吴文婷
;
王立平
;
薛群基【EN】Zhao Wenjie
;
Wang Yanjun
;
Wu Wenting
;
Wang Liping
;
Xue Qunji
摘要:【中文】本发明公开了一种基于仿生超滑表面的防污钛合金材料、其制备方法及应用。所述制备方法包括:采用阳极氧化法对钛合金基底进行处理,在所述钛合金基底表面形成阵列排列的纳米结构层,所述纳米结构层包含不同形貌和/或尺寸的纳米孔或纳米管;以氟硅烷修饰剂对具有纳米结构层的钛合金基底进行化学修饰;以及,向经化学修饰后的钛合金基底表面施加润滑剂,获得基于仿生超滑表面的防污钛合金材料。本发明的仿生超滑表面能够明显的降低细菌在钛合金表面的附着量,具有显著的抗细菌贴附作用和优异的缓释效果,同时其制备方法是一种绿色环保、高效防污的方法,在海洋防污领域具有更为广阔的应用前景。 【EN】The invention discloses an antifouling titanium alloy material based on a bionic super-smooth surface, and a preparation method and application thereof. The preparation method comprises the following steps: processing a titanium alloy substrate by adopting an anodic oxidation method, and forming a nanostructure layer arranged in an array on the surface of the titanium alloy substrate, wherein the nanostructure layer comprises nanopores or nanotubes with different shapes and/or sizes; chemically modifying the titanium alloy substrate with the nanostructure layer by using a fluorosilane modifier; and applying a lubricant to the surface of the chemically modified titanium alloy substrate to obtain the antifouling titanium alloy material based on the bionic super-smooth surface. The bionic super-smooth surface can obviously reduce the attachment amount of bacteria on the surface of the titanium alloy, has obvious antibacterial attachment effect and excellent slow release effect, and meanwhile, the preparation method is an environment-friendly and efficient antifouling method, and has wider application prospect in the field of marine antifouling.
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4:
[发明]
【中文】一种用于长期离体细胞太赫兹生物效应研究的系统及方法 【EN】System and method for researching long-term in-vitro cell terahertz biological effect
申请号:
202010108661.1
公开号:CN111239377A 主分类号:G01N33/48
申请人:
【中文】中国人民解放军第四军医大学【EN】FOURTH MILITARY MEDICAL University
申请日:2020.02.21 公开日:2020.06.05
发明人:
【中文】赵湘辉
;
王文挺
;
刘育明
;
张明
;
武胜昔【EN】Zhao Xianghui
;
Wang Wenting
;
Liu Yuming
;
Zhang Ming
;
Wu Shengxi
摘要:【中文】本发明一种用于长期离体细胞太赫兹生物效应研究的系统及方法,所述系统包括密封固定装置、THz波发射装置、THz波传输装置、细胞外环境维持装置和探测装置;本发明针对贴壁生长的细胞培养物,设计构建了太赫兹波自下而上,长时程辐照细胞的系统与方法。一方面利用太赫兹波传输装置实现将太赫兹源发出的水平发散波改变为垂直汇聚波,该波束对于以薄塑料为基质的细胞培养材料有良好的透过性,因此可以穿过培养基质,作用于正常含有培养液的贴壁细胞生长物,避免了离体细胞周围的培养液对其的阻挡。另一方面利用可控温度样品室,实现细胞在辐照过程中始终处于接近孵箱培养的微环境中,保证长期辐照情况下细胞的存活需求。 【EN】The invention relates to a system and a method for researching a terahertz biological effect of a long-term in-vitro cell, wherein the system comprises a sealing and fixing device, a THz wave emitting device, a THz wave transmission device, an extracellular environment maintaining device and a detection device; the invention designs and constructs a system and a method for irradiating cells by terahertz waves from bottom to top for a long time aiming at cell cultures growing adherent. On one hand, the terahertz wave transmission device is utilized to change the horizontal divergent wave emitted by the terahertz source into the vertical convergent wave, and the wave beam has good permeability to cell culture materials taking thin plastic as a substrate, so that the wave beam can penetrate through the culture substrate to act on adherent cell growths normally containing culture solution, and the culture solution around isolated cells is prevented from blocking the adherent cell growths. On the other hand, the controllable temperature sample chamber is utilized to realize that the cells are always in a microenvironment close to incubator culture in the irradiation process, and the survival requirement of the cells under the long-term irradiation condition is ensured.
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5:
[发明]
【中文】一种介孔锑材料及其制备方法 【EN】Mesoporous antimony material and preparation method thereof
申请号:
202010063525.5
公开号:CN111270089A 主分类号:C22B30/02
申请人:
【中文】沈阳师范大学【EN】SHENYANG NORMAL University
申请日:2020.01.20 公开日:2020.06.12
发明人:
【中文】汤兑海
;
于欢
;
苗思佳
;
赵震
;
张文婷【EN】Tang Duihai
;
Yu Huan
;
Miao Sijia
;
Zhao Zhen
;
Zhang Wenting
摘要:【中文】本发明属于锑材料的制备及应用技术领域,涉及一种介孔锑材料的制备方法。本发明采用一种新的金属还原合成法,以钠钾合金作金属还原剂,以三氯化锑为前驱体,在室温条件下搅拌,制备介孔锑材料,通过控制反应时间达到调节锑材料孔道结构,提高化学物理性能,该材料可以作为钾离子电池负极材料。 【EN】The invention belongs to the technical field of preparation and application of antimony materials, and relates to a preparation method of a mesoporous antimony material. The invention adopts a new metal reduction synthesis method, takes sodium-potassium alloy as a metal reducing agent, takes antimony trichloride as a precursor, stirs the precursor under the condition of room temperature to prepare a mesoporous antimony material, achieves the purposes of adjusting the pore structure of the antimony material and improving the chemical and physical properties by controlling the reaction time, and the material can be used as a potassium ion battery cathode material.
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6:
[发明]
【中文】一种便携式打圈钳 【EN】Portable looper pincers
申请号:
201911144503.5
公开号:CN110854650A 主分类号:H01R43/28
申请人:
【中文】国网浙江省电力有限公司培训中心【EN】State Grid Zhejiang Electric Power Co., Ltd. Training Center
申请日:2019.11.20 公开日:2020.02.28
发明人:
【中文】董绍光
;
叶丽雅
;
王文廷
;
叶润潮
;
陈顺军
;
罗勇
;
龙彪
;
赵琳【EN】Dong Shaoguang
;
Ye Liya
;
Wang Wenting
;
Ye Runchao
;
Chen Shunjun
;
Luo Yong
;
Long Biao
;
Zhao Lin
摘要:【中文】本发明公开了一种便携式打圈钳,涉及手动工具领域。在现场装表接电环节中,导线打圈基本利用尖嘴钳进行绕圈,绕圈大小无法准确控制,费时费力。本发明包括钳体、钳柄和打圈器,打圈器可旋转连接于钳体的中心轴上,钳体上设有端向贯穿的弧形滑槽,打圈器上设有与弧形滑槽宽度相配的旋转导向定位轴,定位轴上位于钳体外侧位置设有用于导线弯曲定型的导线弯曲轮,中心轴上位于钳体外侧位置设有用于导线弯曲定型的导线圈内轴,打圈时,把导线头部插入导线弯曲轮和导线圈内轴之间,导线圈内轴作为圈内径模具,一手握住钳柄,另一手握住打圈器从弧形滑槽一侧旋转到另一侧,完成导线打圈,结构简单,轻巧,打圈精度高,携带方便,便于现场打圈。 【EN】The invention discloses portable looping pliers, and relates to the field of hand tools. In the on-site meter installation and power connection link, the wire looping basically utilizes sharp-nose pliers to perform looping, the size of the looping cannot be accurately controlled, and time and labor are wasted. The wire looping device comprises a clamp body, a clamp handle and a looping device, wherein the looping device is rotatably connected to a central shaft of the clamp body, an arc-shaped sliding groove is formed in the clamp body, the end of the arc-shaped sliding groove penetrates through the clamp body in a penetrating mode, a rotary guide positioning shaft matched with the width of the arc-shaped sliding groove is arranged on the looping device, a wire bending wheel used for bending and shaping a wire is arranged on the positioning shaft and located on the outer side of the clamp body, a wire loop inner shaft used for bending and shaping the wire is arranged on the central shaft and located on the outer side of the clamp body, during looping, the head of the wire is inserted between the wire bending wheel and the wire loop inner shaft, the wire loop inner shaft serves as a loop inner diameter mold, the clamp handle is held by one hand, and the looping device is held by the other hand and rotated from one.
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7:
[发明]
【中文】丹参酮IIA磺酸钠在制备伴随血液中同型半胱氨酸升高的急性或慢性疾病的药物中的应用 【EN】Application of tanshinone IIA sodium sulfonate in preparation of medicine for treating acute or chronic diseases accompanied with increase of homocysteine in blood
申请号:
201811065431.0
公开号:CN110893187A 主分类号:A61K31/58
申请人:
【中文】上海中医药大学附属龙华医院【EN】Longhua Hospital, attached to Shanghai Chinese Medical and Medicinal Univ.
申请日:2018.09.13 公开日:2020.03.20
发明人:
【中文】唐靖一
;
陈昕琳
;
周忠焱
;
马子霖
;
赵外荣
;
肖颖
;
施雯婷【EN】Tang Jingyi
;
Chen Xinlin
;
Zhou Zhongyan
;
Ma Zilin
;
Zhao Wairong
;
Xiao Ying
;
Shi Wenting
摘要:【中文】本发明涉及丹参酮IIA磺酸钠单独或者作为有效成分在制备伴随血液中同型半胱氨酸升高的急性或慢性疾病的药物中的应用。本发明运用血管内皮细胞、心肌细胞、神经细胞、离体血管模型,模拟高同型半胱氨酸对心脑血管系统的损伤作用,发现丹参酮IIA磺酸钠对高同型半胱氨酸引起的心脑血管损伤具有保护和/或治疗作用,弥补了对抗同型半胱氨酸引起的心脑血管损害的保护和/或治疗药物的空白。本发明提供的药物适用于引起血液内同型半胱氨酸异常升高的疾病,只需要在血液内达到有效浓度即可发挥对抗同型半胱氨酸引起心脑血管损伤的保护和/或治疗作用,为血液中同型半胱氨酸升高疾病的心脑血管损伤治疗提供了更好的选择。 【EN】The invention relates to application of tanshinone IIA sodium sulfonate in preparation of drugs for treating acute or chronic diseases accompanied with increase of homocysteine in blood independently or as an effective component. The invention uses vascular endothelial cells, myocardial cells, nerve cells and isolated blood vessel models to simulate the damage effect of homocysteine on the cardiovascular and cerebrovascular systems, finds that the tanshinone IIA sodium sulfonate has the protection and/or treatment effect on the cardiovascular and cerebrovascular damage caused by homocysteine, and fills the blank of protection and/or treatment medicines for resisting the cardiovascular and cerebrovascular damage caused by homocysteine. The medicine provided by the invention is suitable for diseases causing abnormal increase of homocysteine in blood, can play a role in protecting and/or treating cardiovascular and cerebrovascular injuries caused by resisting homocysteine only by reaching effective concentration in blood, and provides a better choice for treating cardiovascular and cerebrovascular injuries caused by diseases causing the increase of homocysteine in the blood.
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8:
[发明]
【中文】报销流程的跟踪方法、装置、计算机设备和存储介质 【EN】Reimbursement process tracking method and device, computer equipment and storage medium
申请号:
201911382835.7
公开号:CN111222846A 主分类号:G06Q10/10
申请人:
【中文】广东德诚科教有限公司【EN】GUANGDONG DECHENG SCIENTIFIC EDUCATION Co.,Ltd.
申请日:2019.12.27 公开日:2020.06.02
发明人:
【中文】喻志翀
;
柯维海
;
黄建超
;
张文停
;
黄彩婷
;
胡永松
;
赵育钟【EN】Yu Zhili
;
Ke Weihai
;
Huang Jianchao
;
Zhang Wenting
;
Huang Caiting
;
Hu Yongsong
;
Zhao Yuzhong
摘要:【中文】本申请提供一种报销流程的跟踪方法、装置、计算机设备和存储介质。该方法包括:获取待报销单据信息,待报销单据信息包括待报销文件的类型信息、金额信息、归属单位;根据待报销单据信息,生成单据投递标识码;根据单据投递标识码对应的投递柜标识信息,输出第一提示信息,第一提示信息用于提示待报销文件对应的投递方用户投递待报销文件至投递柜标识信息对应的投递柜中;确定投递柜接收到待报销文件时,向待报销文件对应的收取方终端发送收取待报销文件的第二提示信息。采用本申请方法能够避免现有方法中投递方用户亲自往返报销部门投递待报销文件以及查看报销状态导致的人力时间浪费问题,节省了人力和时间成本,提高了报销效率。 【EN】The application provides a method and a device for tracking reimbursement processes, computer equipment and a storage medium. The method comprises the following steps: acquiring information of a to-be-reimbursed document, wherein the information of the to-be-reimbursed document comprises type information, amount information and an attribution unit of the to-be-reimbursed document; generating a document delivery identification code according to the information of the document to be reimbursed; outputting first prompt information according to the delivery cabinet identification information corresponding to the document delivery identification code, wherein the first prompt information is used for prompting a delivery party user corresponding to the to-be-reimbursed document to deliver the to-be-reimbursed document to the delivery cabinet corresponding to the delivery cabinet identification information; and when the delivery cabinet is determined to receive the file to be reimbursed, sending second prompt information for receiving the file to be reimbursed to a receiving party terminal corresponding to the file to be reimbursed. By adopting the method, the problem of manpower and time waste caused by the fact that the user of the delivery party personally returns the reimbursement department to deliver the file to be reimbursed and check the reimbursement state in the existing method can be solved, the manpower and time cost is saved, and the reimbursement efficiency is improved.
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9:
[发明]
【中文】考核量化值获取方法、装置、设备及可读存储介质 【EN】Assessment quantitative value obtaining method, device and equipment and readable storage medium
申请号:
201911380186.7
公开号:CN111209731A 主分类号:G06F40/18
申请人:
【中文】广东德诚科教有限公司【EN】GUANGDONG DECHENG SCIENTIFIC EDUCATION Co.,Ltd.
申请日:2019.12.27 公开日:2020.05.29
发明人:
【中文】柯维海
;
喻志翀
;
黄建超
;
张文停
;
黄彩婷
;
赵育钟
;
胡永松【EN】Ke Weihai
;
Yu Zhili
;
Huang Jianchao
;
Zhang Wenting
;
Huang Caiting
;
Zhao Yuzhong
;
Hu Yongsong
摘要:【中文】本申请提供一种考核量化值获取方法、装置、设备以及可读存储介质。该方法包括:获取待考核对象的属性信息,属性信息表征所述待考核对象对应用户的职责范围;获取属性信息对应的预设考核模板,预设考核模板包含考核项类型与至少一个待考核内容之间的对应关系,以及所述待考核对象的考核主体类型与考核主体之间的对应关系,考核项类型包括普通项类型、加分项类型与扣分项类型中的至少一个;采用预设考核模板确定所述待考核对象对应用户的目标考核量化值;本申请通过采用与待考核对象的属性信息对应的预设考核模板,确定待考核对象对应用户的目标考核量化值,既省时省力,也提高了考核模板的灵活性和效率。 【EN】The application provides an assessment quantitative value obtaining method, device and equipment and a readable storage medium. The method comprises the following steps: acquiring attribute information of an object to be assessed, wherein the attribute information represents a duty range of a user corresponding to the object to be assessed; acquiring a preset assessment template corresponding to the attribute information, wherein the preset assessment template comprises a corresponding relation between an assessment item type and at least one content to be assessed and a corresponding relation between an assessment main body type of the object to be assessed and an assessment main body, and the assessment item type comprises at least one of a common item type, an addend item type and a deduction item type; determining a target assessment quantitative value of a user corresponding to the object to be assessed by adopting a preset assessment template; according to the method and the device, the preset assessment template corresponding to the attribute information of the object to be assessed is adopted to determine the target assessment quantitative value of the user corresponding to the object to be assessed, so that time and labor are saved, and the flexibility and efficiency of the assessment template are improved.
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[发明]
【中文】研究高频电磁辐射对体外可兴奋细胞生物电效应的系统及方法 【EN】System and method for researching bioelectric effect of high-frequency electromagnetic radiation on in-vitro excitable cells
申请号:
202010121603.2
公开号:CN111239134A 主分类号:G01N21/84
申请人:
【中文】中国人民解放军第四军医大学【EN】FOURTH MILITARY MEDICAL University
申请日:2020.02.26 公开日:2020.06.05
发明人:
【中文】王文挺
;
赵湘辉
;
张海锋
;
刘海鹰
;
张明
;
武胜昔【EN】Wang Wenting
;
Zhao Xianghui
;
Zhang Haifeng
;
Liu Haiying
;
Zhang Ming
;
Wu Shengxi
摘要:【中文】本发明研究高频电磁辐射对体外可兴奋细胞生物电效应的系统及方法,针对贴壁生长的培养细胞、利用电生理记录系统和显微镜观察系统,设计构建了太赫兹波自上而下,可以实现对贴壁生长的体外培养神经元及其它可兴奋细胞实时辐照太赫兹及其电生理特征的同步检测,系统操作简单,可重复性强。一方面我们将太赫兹源整合入电生理记录系统中,固定在电动三维显微操纵器上,实现自由、精确移动太赫兹源。同时,将肉眼不可见的太赫兹波和可见光激光定位瞄准器结合,确定太赫兹波照射位置。另一方面,通过控制电生理记录小室即培养皿的液面高度,减少太赫兹波在液体中的衰减程度,实现对神经元的实时照射并实时记录电生理学指标。 【EN】The invention relates to a system and a method for researching the bioelectric effect of high-frequency electromagnetic radiation on in-vitro excitable cells, which designs and constructs a terahertz wave from top to bottom aiming at cultured cells growing adherent, an electrophysiological recording system and a microscope observation system, can realize the synchronous detection of real-time irradiation terahertz of the in-vitro cultured neurons and other excitable cells growing adherent and the electrophysiological characteristics thereof, and has the advantages of simple system operation and strong repeatability. On one hand, the terahertz source is integrated into an electrophysiological recording system and fixed on an electric three-dimensional micromanipulator, so that the terahertz source can be freely and accurately moved. Meanwhile, the terahertz wave invisible to naked eyes is combined with the visible light laser positioning sighting device to determine the terahertz wave irradiation position. On the other hand, the attenuation degree of the terahertz waves in the liquid is reduced by controlling the liquid level height of the electrophysiological recording cell, namely the culture dish, so that the neurons can be irradiated in real time and electrophysiological indexes can be recorded in real time.
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