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Zhu Meipeng
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[发明]
【中文】一种复方鱼腥草合剂及其制备方法 【EN】Compound houttuynia cordata mixture and preparation method thereof
申请号:
201911332856.8
公开号:CN111067963A 主分类号:A61K36/78
申请人:
【中文】浙江康恩贝中药有限公司【EN】ZHEJIANG CONBA TRADITIONAL CHINESE MEDICINE Co.,Ltd.
申请日:2019.12.23 公开日:2020.04.28
发明人:
【中文】金汉台
;
金志文
;
朱美鹏
;
孙斌
;
林剑峰
;
严道荣
;
高加文
;
叶菊萍
;
孟智勇【EN】Jin Hantai
;
Jin Zhiwen
;
Zhu Meipeng
;
Sun Bin
;
Lin Jianfeng
;
Yan Daorong
;
Gao Jiawen
;
Ye Juping
;
Meng Zhiyong
摘要:【中文】本发明公开了一种复方鱼腥草合剂的制备方法,以鱼腥草、黄芩、板蓝根、连翘和金银花为主药药材制备,包括如下步骤:煎煮、清膏、醇沉、水沉、制剂。本发明提供的复方鱼腥草合剂处方及制备工艺,通过醇沉时温度的控制、水沉时pH值的调节、制剂时泊洛沙姆的增加,不但能增加有效成分黄芩苷、连翘苷的含量,且含量优于市售的复方鱼腥草合剂,还能大大提高成品的稳定性,即使长期放置后也仍未出现沉淀。 【EN】The invention discloses a preparation method of a compound houttuynia cordata mixture, which is prepared by taking houttuynia cordata, scutellaria baicalensis, isatis root, fructus forsythiae and honeysuckle as main medicinal materials and comprises the following steps: decocting, making fluid extract, precipitating with ethanol, precipitating with water, and making into preparation. According to the compound houttuynia cordata mixture formula and the preparation process, the contents of active ingredients baicalin and phillyrin can be increased through the control of the temperature during alcohol precipitation, the adjustment of the pH value during water precipitation and the increase of poloxamer during preparation, the content of the active ingredients baicalin and phillyrin is superior to that of a compound houttuynia cordata mixture sold in the market, the stability of a finished product can be greatly improved, and no precipitate is generated even after the mixture is placed for a long time.
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